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1.

Retinoid-related orphan receptor gamma controls immunoglobulin production and Th1/Th2 cytokine balance in the adaptive immune response to allergen.

Tilley SL, Jaradat M, Stapleton C, Dixon D, Hua X, Erikson CJ, McCaskill JG, Chason KD, Liao G, Jania L, Koller BH, Jetten AM.

J Immunol. 2007 Mar 1;178(5):3208-18.

2.

Th type 1-stimulating activity of lung macrophages inhibits Th2-mediated allergic airway inflammation by an IFN-gamma-dependent mechanism.

Tang C, Inman MD, van Rooijen N, Yang P, Shen H, Matsumoto K, O'Byrne PM.

J Immunol. 2001 Feb 1;166(3):1471-81.

3.

Intranasal IL-12 produces discreet pulmonary and systemic effects on allergic inflammation and airway reactivity.

Matsuse H, Kong X, Hu J, Wolf SF, Lockey RF, Mohapatra SS.

Int Immunopharmacol. 2003 Apr;3(4):457-68.

PMID:
12689651
4.

The ROR nuclear orphan receptor subfamily: critical regulators of multiple biological processes.

Jetten AM, Kurebayashi S, Ueda E.

Prog Nucleic Acid Res Mol Biol. 2001;69:205-47. Review.

PMID:
11550795
5.
6.

IFN-gamma attenuates antigen-induced overall immune response in the airway as a Th1-type immune regulatory cytokine.

Nakagome K, Okunishi K, Imamura M, Harada H, Matsumoto T, Tanaka R, Miyazaki J, Yamamoto K, Dohi M.

J Immunol. 2009 Jul 1;183(1):209-20. doi: 10.4049/jimmunol.0802712.

7.

Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease.

Horvat JC, Starkey MR, Kim RY, Beagley KW, Preston JA, Gibson PG, Foster PS, Hansbro PM.

J Immunol. 2010 Apr 15;184(8):4159-69. doi: 10.4049/jimmunol.0902287. Epub 2010 Mar 12.

8.

TH2 and TH1 lung inflammation induced by airway allergen sensitization with low and high doses of double-stranded RNA.

Jeon SG, Oh SY, Park HK, Kim YS, Shim EJ, Lee HS, Oh MH, Bang B, Chun EY, Kim SH, Gho YS, Zhu Z, Kim YY, Kim YK.

J Allergy Clin Immunol. 2007 Oct;120(4):803-12. Epub 2007 Jul 5.

PMID:
17610940
9.

Long-chain polyunsaturated fatty acids are consumed during allergic inflammation and affect T helper type 1 (Th1)- and Th2-mediated hypersensitivity differently.

Johansson S, Lönnqvist A, Ostman S, Sandberg AS, Wold AE.

Clin Exp Immunol. 2010 Jun;160(3):411-9. doi: 10.1111/j.1365-2249.2010.04107.x. Epub 2010 Feb 10.

10.

Prenatal initiation of endotoxin airway exposure prevents subsequent allergen-induced sensitization and airway inflammation in mice.

Gerhold K, Avagyan A, Seib C, Frei R, Steinle J, Ahrens B, Dittrich AM, Blumchen K, Lauener R, Hamelmann E.

J Allergy Clin Immunol. 2006 Sep;118(3):666-73. Epub 2006 Jul 20.

PMID:
16950286
11.

Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis.

Kurebayashi S, Ueda E, Sakaue M, Patel DD, Medvedev A, Zhang F, Jetten AM.

Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):10132-7.

12.

15-lipoxygenase metabolites play an important role in the development of a T-helper type 1 allergic inflammation induced by double-stranded RNA.

Jeon SG, Moon HG, Kim YS, Choi JP, Shin TS, Hong SW, Tae YM, Kim SH, Zhu Z, Gho YS, Kim YK.

Clin Exp Allergy. 2009 Jun;39(6):908-17. doi: 10.1111/j.1365-2222.2009.03211.x. Epub 2009 Feb 25.

PMID:
19260872
13.

Effects of endogenous glucocorticoids on allergic inflammation and T(H)1 /T(H)2 balance in airway allergic disease.

Zhang S, Shen Z, Hu G, Liu R, Zhang X.

Ann Allergy Asthma Immunol. 2009 Dec;103(6):525-34. doi: 10.1016/S1081-1206(10)60270-0.

PMID:
20084847
14.

BCG priming of dendritic cells enhances T regulatory and Th1 function and suppresses allergen-induced Th2 function in vitro and in vivo.

Ahrens B, Gruber C, Rha RD, Freund T, Quarcoo D, Awagyan A, Hutloff A, Dittrich AM, Wahn U, Hamelmann E.

Int Arch Allergy Immunol. 2009;150(3):210-20. doi: 10.1159/000222673. Epub 2009 Jun 3.

PMID:
19494518
15.

Dynamics of gut mucosal and systemic Th1/Th2 cytokine responses in interferon-gamma and interleukin-12p40 knock out mice during primary and challenge Cryptosporidium parvum infection.

Tessema TS, Schwamb B, Lochner M, Förster I, Jakobi V, Petry F.

Immunobiology. 2009;214(6):454-66. doi: 10.1016/j.imbio.2008.11.015. Epub 2009 Jan 19.

PMID:
19155092
16.

Divergent effects of biolistic gene transfer in a mouse model of allergic airway inflammation.

Zindler E, Gehrke N, Luft C, Reuter S, Taube C, Finotto S, Reske-Kunz AB, Sudowe S.

Am J Respir Cell Mol Biol. 2008 Jan;38(1):38-46. Epub 2007 Jul 19.

PMID:
17641297
17.

Lack of lymphoid chemokines CCL19 and CCL21 enhances allergic airway inflammation in mice.

Xu B, Aoyama K, Kusumoto M, Matsuzawa A, Butcher EC, Michie SA, Matsuyama T, Takeuchi T.

Int Immunol. 2007 Jun;19(6):775-84. Epub 2007 May 19.

18.

Absence of Toll-IL-1 receptor 8/single immunoglobulin IL-1 receptor-related molecule reduces house dust mite-induced allergic airway inflammation in mice.

Barry J, Loh Z, Collison A, Mazzone S, Lalwani A, Zhang V, Davidson S, Wybacz E, Garlanda C, Mantovani A, Mattes J, Foster PS, Phipps S.

Am J Respir Cell Mol Biol. 2013 Sep;49(3):481-90. doi: 10.1165/rcmb.2012-0425OC.

PMID:
23614768
19.

RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.

Leppkes M, Becker C, Ivanov II, Hirth S, Wirtz S, Neufert C, Pouly S, Murphy AJ, Valenzuela DM, Yancopoulos GD, Becher B, Littman DR, Neurath MF.

Gastroenterology. 2009 Jan;136(1):257-67. doi: 10.1053/j.gastro.2008.10.018. Epub 2008 Oct 9.

PMID:
18992745
20.

Cellular FLIP long form-transgenic mice manifest a Th2 cytokine bias and enhanced allergic airway inflammation.

Wu W, Rinaldi L, Fortner KA, Russell JQ, Tschopp J, Irvin C, Budd RC.

J Immunol. 2004 Apr 15;172(8):4724-32.

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