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Results: 1 to 20 of 104

1.

Interleukin-1-induced NF-kappaB activation is NEMO-dependent but does not require IKKbeta.

Solt LA, Madge LA, Orange JS, May MJ.

J Biol Chem. 2007 Mar 23;282(12):8724-33. Epub 2007 Jan 23.

PMID:
17244613
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation.

Solt LA, Madge LA, May MJ.

J Biol Chem. 2009 Oct 2;284(40):27596-608. doi: 10.1074/jbc.M109.047563. Epub 2009 Aug 7.

PMID:
19666475
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program.

Li X, Massa PE, Hanidu A, Peet GW, Aro P, Savitt A, Mische S, Li J, Marcu KB.

J Biol Chem. 2002 Nov 22;277(47):45129-40. Epub 2002 Sep 6.

PMID:
12221085
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Regulation and function of IKK and IKK-related kinases.

Häcker H, Karin M.

Sci STKE. 2006 Oct 17;2006(357):re13. Review.

PMID:
17047224
[PubMed - indexed for MEDLINE]
5.

IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway.

Adli M, Merkhofer E, Cogswell P, Baldwin AS.

PLoS One. 2010 Feb 25;5(2):e9428. doi: 10.1371/journal.pone.0009428.

PMID:
20195534
[PubMed - indexed for MEDLINE]
Free PMC Article
6.
7.

Phosphorylation of serine 68 in the IkappaB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-alpha-induced NF-kappaB activity.

Palkowitsch L, Leidner J, Ghosh S, Marienfeld RB.

J Biol Chem. 2008 Jan 4;283(1):76-86. Epub 2007 Oct 31.

PMID:
17977820
[PubMed - indexed for MEDLINE]
Free Article
8.

Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC.

Matta H, Gopalakrishnan R, Graham C, Tolani B, Khanna A, Yi H, Suo Y, Chaudhary PM.

PLoS One. 2012;7(5):e36601. doi: 10.1371/journal.pone.0036601. Epub 2012 May 8.

PMID:
22590573
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

NEMO oligomerization in the dynamic assembly of the IkappaB kinase core complex.

Fontan E, Traincard F, Levy SG, Yamaoka S, Véron M, Agou F.

FEBS J. 2007 May;274(10):2540-51. Epub 2007 Apr 10.

PMID:
17419723
[PubMed - indexed for MEDLINE]
10.

Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

Sizemore N, Lerner N, Dombrowski N, Sakurai H, Stark GR.

J Biol Chem. 2002 Feb 8;277(6):3863-9. Epub 2001 Dec 3.

PMID:
11733537
[PubMed - indexed for MEDLINE]
Free Article
11.

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway.

Takaesu G, Surabhi RM, Park KJ, Ninomiya-Tsuji J, Matsumoto K, Gaynor RB.

J Mol Biol. 2003 Feb 7;326(1):105-15.

PMID:
12547194
[PubMed - indexed for MEDLINE]
12.

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected].

Wu CJ, Conze DB, Li T, Srinivasula SM, Ashwell JD.

Nat Cell Biol. 2006 Apr;8(4):398-406. Epub 2006 Mar 19. Erratum in: Nat Cell Biol. 2006 Apr;8(4):424.

PMID:
16547522
[PubMed - indexed for MEDLINE]
13.

Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer.

Nottingham LK, Yan CH, Yang X, Si H, Coupar J, Bian Y, Cheng TF, Allen C, Arun P, Gius D, Dang L, Van Waes C, Chen Z.

Oncogene. 2014 Feb 27;33(9):1135-47. doi: 10.1038/onc.2013.49. Epub 2013 Mar 4.

PMID:
23455325
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The IkappaB kinase complex: master regulator of NF-kappaB signaling.

Solt LA, May MJ.

Immunol Res. 2008;42(1-3):3-18. doi: 10.1007/s12026-008-8025-1. Review.

PMID:
18626576
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis.

Dai S, Hirayama T, Abbas S, Abu-Amer Y.

J Biol Chem. 2004 Sep 3;279(36):37219-22. Epub 2004 Jul 13.

PMID:
15252035
[PubMed - indexed for MEDLINE]
Free Article
16.

Novel cross-talk within the IKK family controls innate immunity.

Clark K, Peggie M, Plater L, Sorcek RJ, Young ER, Madwed JB, Hough J, McIver EG, Cohen P.

Biochem J. 2011 Feb 15;434(1):93-104. doi: 10.1042/BJ20101701.

PMID:
21138416
[PubMed - indexed for MEDLINE]
Free Article
17.

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis.

Li ZW, Chu W, Hu Y, Delhase M, Deerinck T, Ellisman M, Johnson R, Karin M.

J Exp Med. 1999 Jun 7;189(11):1839-45.

PMID:
10359587
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases.

Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ET Jr, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC.

Mol Cell Biol. 1998 Sep;18(9):5157-65.

PMID:
9710600
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Inhibition of the NEMO/IKKβ association complex formation, a novel mechanism associated with the NF-κB activation suppression by Withania somnifera's key metabolite withaferin A.

Grover A, Shandilya A, Punetha A, Bisaria VS, Sundar D.

BMC Genomics. 2010 Dec 2;11 Suppl 4:S25. doi: 10.1186/1471-2164-11-S4-S25.

PMID:
21143809
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The RET/PTC3 oncogene activates classical NF-κB by stabilizing NIK.

Neely RJ, Brose MS, Gray CM, McCorkell KA, Leibowitz JM, Ma C, Rothstein JL, May MJ.

Oncogene. 2011 Jan 6;30(1):87-96. doi: 10.1038/onc.2010.396. Epub 2010 Sep 6.

PMID:
20818435
[PubMed - indexed for MEDLINE]
Free PMC Article

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