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Results: 1 to 20 of 100

1.

Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism.

Pogue-Geile KL, Chen R, Bronner MP, Crnogorac-Jurcevic T, Moyes KW, Dowen S, Otey CA, Crispin DA, George RD, Whitcomb DC, Brentnall TA.

PLoS Med. 2006 Dec;3(12):e516.

PMID:
17194196
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells.

Salaria SN, Illei P, Sharma R, Walter KM, Klein AP, Eshleman JR, Maitra A, Schulick R, Winter J, Ouellette MM, Goggins M, Hruban R.

Cancer Biol Ther. 2007 Mar;6(3):324-8. Epub 2007 Mar 24.

PMID:
17404500
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

[Familial pancreatic cancer and the palladin gene: a new look at cancer mechanisms].

Gilgenkrantz S.

Med Sci (Paris). 2007 Mar;23(3):232-4. French. No abstract available.

PMID:
17349274
[PubMed - indexed for MEDLINE]
4.

The P239S palladin variant does not account for a significant fraction of hereditary or early onset pancreas cancer.

Zogopoulos G, Rothenmund H, Eppel A, Ash C, Akbari MR, Hedley D, Narod SA, Gallinger S.

Hum Genet. 2007 Jun;121(5):635-7. Epub 2007 Apr 6. Erratum in: Hum Genet. 2007 Jul;121(6):767. Zogopoulous, George [corrected to Zogopoulos, George].

PMID:
17415588
[PubMed - indexed for MEDLINE]
5.

Absence of deleterious palladin mutations in patients with familial pancreatic cancer.

Klein AP, Borges M, Griffith M, Brune K, Hong SM, Omura N, Hruban RH, Goggins M.

Cancer Epidemiol Biomarkers Prev. 2009 Apr;18(4):1328-30. doi: 10.1158/1055-9965.EPI-09-0056. Epub 2009 Mar 31.

PMID:
19336541
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Familial pancreatic-cancer gene found.

Bradbury J.

Lancet Oncol. 2007 Jan;8(1):14. No abstract available.

PMID:
17348120
[PubMed - indexed for MEDLINE]
7.

Arousal of cancer-associated stroma: overexpression of palladin activates fibroblasts to promote tumor invasion.

Brentnall TA, Lai LA, Coleman J, Bronner MP, Pan S, Chen R.

PLoS One. 2012;7(1):e30219. doi: 10.1371/journal.pone.0030219. Epub 2012 Jan 23.

PMID:
22291919
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Palladin mutation causes familial pancreatic cancer: absence in European families.

Slater E, Amrillaeva V, Fendrich V, Bartsch D, Earl J, Vitone LJ, Neoptolemos JP, Greenhalf W.

PLoS Med. 2007 Apr;4(4):e164. No abstract available.

PMID:
17455999
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Evaluation of the 4q32-34 locus in European familial pancreatic cancer.

Earl J, Yan L, Vitone LJ, Risk J, Kemp SJ, McFaul C, Neoptolemos JP, Greenhalf W; European Registry of Hereditary Pancreatitis and Familial Pancreatic Cancer, Kress R, Sina-Frey M, Hahn SA, Rieder H, Bartsch DK; German National Case Collection for Familial Pancreatic Cancer.

Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):1948-55.

PMID:
17035404
[PubMed - indexed for MEDLINE]
Free Article
10.

Molecular pathology of primary and metastatic ductal pancreatic lesions: analyses of mutations and expression of the p53, mdm-2, and p21/WAF-1 genes in sporadic and familial lesions.

Ruggeri BA, Huang L, Berger D, Chang H, Klein-Szanto AJ, Goodrow T, Wood M, Obara T, Heath CW, Lynch H.

Cancer. 1997 Feb 15;79(4):700-16.

PMID:
9024708
[PubMed - indexed for MEDLINE]
11.

The actin-bundling protein palladin is an Akt1-specific substrate that regulates breast cancer cell migration.

Chin YR, Toker A.

Mol Cell. 2010 May 14;38(3):333-44. doi: 10.1016/j.molcel.2010.02.031.

PMID:
20471940
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Linkage analysis of chromosome 4 in families with familial pancreatic cancer.

Klein AP, de Andrade M, Hruban RH, Bondy M, Schwartz AG, Gallinger S, Lynch HT, Syngal S, Rabe KG, Goggins MG, Petersen GM.

Cancer Biol Ther. 2007 Mar;6(3):320-3. Epub 2007 Mar 15.

PMID:
17312386
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Isoform-specific upregulation of palladin in human and murine pancreas tumors.

Goicoechea SM, Bednarski B, Stack C, Cowan DW, Volmar K, Thorne L, Cukierman E, Rustgi AK, Brentnall T, Hwang RF, McCulloch CA, Yeh JJ, Bentrem DJ, Hochwald SN, Hingorani SR, Kim HJ, Otey CA.

PLoS One. 2010 Apr 26;5(4):e10347. doi: 10.1371/journal.pone.0010347.

PMID:
20436683
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, BRCA1, and BRCA2 mutations.

Lal G, Liu G, Schmocker B, Kaurah P, Ozcelik H, Narod SA, Redston M, Gallinger S.

Cancer Res. 2000 Jan 15;60(2):409-16.

PMID:
10667595
[PubMed - indexed for MEDLINE]
Free Article
15.

The role of palladin in actin organization and cell motility.

Goicoechea SM, Arneman D, Otey CA.

Eur J Cell Biol. 2008 Sep;87(8-9):517-25. doi: 10.1016/j.ejcb.2008.01.010. Epub 2008 Mar 14. Review.

PMID:
18342394
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Molecular analysis of the interaction between palladin and alpha-actinin.

Rönty M, Taivainen A, Moza M, Otey CA, Carpén O.

FEBS Lett. 2004 May 21;566(1-3):30-4.

PMID:
15147863
[PubMed - indexed for MEDLINE]
Free Article
17.

Characterization of human Rab20 overexpressed in exocrine pancreatic carcinoma.

Amillet JM, Ferbus D, Real FX, Antony C, Muleris M, Gress TM, Goubin G.

Hum Pathol. 2006 Mar;37(3):256-63.

PMID:
16613320
[PubMed - indexed for MEDLINE]
18.

Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts.

Goicoechea SM, García-Mata R, Staub J, Valdivia A, Sharek L, McCulloch CG, Hwang RF, Urrutia R, Yeh JJ, Kim HJ, Otey CA.

Oncogene. 2014 Mar 6;33(10):1265-73. doi: 10.1038/onc.2013.68. Epub 2013 Mar 25.

PMID:
23524582
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Molecular genetic alterations in ductal pancreatic adenocarcinomas.

Kern SE.

Med Clin North Am. 2000 May;84(3):691-5, xi. Review.

PMID:
10872425
[PubMed - indexed for MEDLINE]
20.

A new susceptibility locus for autosomal dominant pancreatic cancer maps to chromosome 4q32-34.

Eberle MA, Pfützer R, Pogue-Geile KL, Bronner MP, Crispin D, Kimmey MB, Duerr RH, Kruglyak L, Whitcomb DC, Brentnall TA.

Am J Hum Genet. 2002 Apr;70(4):1044-8. Epub 2002 Feb 27.

PMID:
11870593
[PubMed - indexed for MEDLINE]
Free PMC Article

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