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Items: 1 to 20 of 96

1.

A "silent" polymorphism in the MDR1 gene changes substrate specificity.

Kimchi-Sarfaty C, Oh JM, Kim IW, Sauna ZE, Calcagno AM, Ambudkar SV, Gottesman MM.

Science. 2007 Jan 26;315(5811):525-8. Epub 2006 Dec 21. Erratum in: Science. 2011 oCT 7;334(6052):39. Science. 2007 Nov 30;318(5855):1382-3.

2.

Genetics. SNPs, silent but not invisible.

Komar AA.

Science. 2007 Jan 26;315(5811):466-7. Epub 2006 Dec 21. No abstract available.

PMID:
17185559
3.

MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer.

Fung KL, Pan J, Ohnuma S, Lund PE, Pixley JN, Kimchi-Sarfaty C, Ambudkar SV, Gottesman MM.

Cancer Res. 2014 Jan 15;74(2):598-608. doi: 10.1158/0008-5472.CAN-13-2064. Epub 2013 Dec 4.

4.

Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog.

De Rosa MF, Ackerley C, Wang B, Ito S, Clarke DM, Lingwood C.

J Biol Chem. 2008 Feb 22;283(8):4501-11. Epub 2007 Nov 13.

5.

Transport of phosphatidylcholine in MDR3-negative epithelial cell lines via drug-induced MDR1 P-glycoprotein.

Abulrob AG, Gumbleton M.

Biochem Biophys Res Commun. 1999 Aug 19;262(1):121-6.

PMID:
10448079
6.
7.

Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition.

Zhou SF.

Xenobiotica. 2008 Jul;38(7-8):802-32. doi: 10.1080/00498250701867889 . Review.

PMID:
18668431
8.

Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms.

Meissner K, Jedlitschky G, Meyer zu Schwabedissen H, Dazert P, Eckel L, Vogelgesang S, Warzok RW, Böhm M, Lehmann C, Wendt M, Cascorbi I, Kroemer HK.

Pharmacogenetics. 2004 Jun;14(6):381-5.

PMID:
15247630
9.

Molecular evidence and functional expression of P-glycoprotein (MDR1) in human and rabbit cornea and corneal epithelial cell lines.

Dey S, Patel J, Anand BS, Jain-Vakkalagadda B, Kaliki P, Pal D, Ganapathy V, Mitra AK.

Invest Ophthalmol Vis Sci. 2003 Jul;44(7):2909-18.

PMID:
12824231
10.

The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells.

Hitzl M, Drescher S, van der Kuip H, Schäffeler E, Fischer J, Schwab M, Eichelbaum M, Fromm MF.

Pharmacogenetics. 2001 Jun;11(4):293-8.

PMID:
11434506
11.

P-glycoprotein (MDR1) functional activity in human alveolar epithelial cell monolayers.

Endter S, Becker U, Daum N, Huwer H, Lehr CM, Gumbleton M, Ehrhardt C.

Cell Tissue Res. 2007 Apr;328(1):77-84. Epub 2006 Dec 13.

PMID:
17165089
12.
13.
14.
15.

Expression of the MDR1 gene and P-glycoprotein in canine mast cell tumor cell lines.

Nakaichi M, Takeshita Y, Okuda M, Nakamoto Y, Itamoto K, Une S, Sasaki N, Kadosawa T, Takahashi T, Taura Y.

J Vet Med Sci. 2007 Feb;69(2):111-5.

16.

Induction of multidrug resistance in MOLT-4 cells by anticancer agents is closely related to increased expression of functional P-glycoprotein and MDR1 mRNA.

Liu ZL, Onda K, Tanaka S, Toma T, Hirano T, Oka K.

Cancer Chemother Pharmacol. 2002 May;49(5):391-7. Epub 2002 Feb 14.

PMID:
11976833
17.
18.

A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.

Fung KL, Gottesman MM.

Biochim Biophys Acta. 2009 May;1794(5):860-71. doi: 10.1016/j.bbapap.2009.02.014. Epub 2009 Mar 11. Review.

19.

MDR1 C2005T polymorphism changes substrate specificity.

Liu L, Fan L, Peng X, Hu D, Zhou H.

Cancer Chemother Pharmacol. 2010 Aug;66(3):617-23. doi: 10.1007/s00280-010-1308-y. Epub 2010 Mar 23.

PMID:
20309692
20.

P-Glycoprotein expression in human retinal pigment epithelium cell lines.

Constable PA, Lawrenson JG, Dolman DE, Arden GB, Abbott NJ.

Exp Eye Res. 2006 Jul;83(1):24-30. Epub 2006 Mar 10.

PMID:
16530756
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