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Items: 1 to 20 of 104

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Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling.

Varadan R, Assfalg M, Haririnia A, Raasi S, Pickart C, Fushman D.

J Biol Chem. 2004 Feb 20;279(8):7055-63. Epub 2003 Nov 25.

4.

Structural basis for distinct roles of Lys63- and Lys48-linked polyubiquitin chains.

Tenno T, Fujiwara K, Tochio H, Iwai K, Morita EH, Hayashi H, Murata S, Hiroaki H, Sato M, Tanaka K, Shirakawa M.

Genes Cells. 2004 Oct;9(10):865-75. Erratum in: Genes Cells. 2004 Nov;9(11):1137.

5.

Direct catalysis of lysine 48-linked polyubiquitin chains by the ubiquitin-activating enzyme.

Huzil JT, Pannu R, Ptak C, Garen G, Ellison MJ.

J Biol Chem. 2007 Dec 28;282(52):37454-60. Epub 2007 Oct 19.

6.

Orchestra for assembly and fate of polyubiquitin chains.

Kuhlbrodt K, Mouysset J, Hoppe T.

Essays Biochem. 2005;41:1-14. Review.

PMID:
16250894
7.

Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T.

Wilkinson KD, Tashayev VL, O'Connor LB, Larsen CN, Kasperek E, Pickart CM.

Biochemistry. 1995 Nov 7;34(44):14535-46.

PMID:
7578059
8.

Polyubiquitin chains: polymeric protein signals.

Pickart CM, Fushman D.

Curr Opin Chem Biol. 2004 Dec;8(6):610-6. Review.

PMID:
15556404
9.

Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation.

Eddins MJ, Carlile CM, Gomez KM, Pickart CM, Wolberger C.

Nat Struct Mol Biol. 2006 Oct;13(10):915-20. Epub 2006 Sep 17.

PMID:
16980971
10.

A snapshot of ubiquitin chain elongation: lysine 48-tetra-ubiquitin slows down ubiquitination.

Kovacev J, Wu K, Spratt DE, Chong RA, Lee C, Nayak J, Shaw GS, Pan ZQ.

J Biol Chem. 2014 Mar 7;289(10):7068-81. doi: 10.1074/jbc.M113.530576. Epub 2014 Jan 24.

11.

Human Cdc34 employs distinct sites to coordinate attachment of ubiquitin to a substrate and assembly of polyubiquitin chains.

Gazdoiu S, Yamoah K, Wu K, Pan ZQ.

Mol Cell Biol. 2007 Oct;27(20):7041-52. Epub 2007 Aug 13.

12.

Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains.

Sato Y, Yoshikawa A, Yamagata A, Mimura H, Yamashita M, Ookata K, Nureki O, Iwai K, Komada M, Fukai S.

Nature. 2008 Sep 18;455(7211):358-62. doi: 10.1038/nature07254. Epub 2008 Aug 31. Erratum in: Nature. 2008 Nov 13;456(7219):274.

PMID:
18758443
13.

Structural determinants for selective recognition of a Lys48-linked polyubiquitin chain by a UBA domain.

Varadan R, Assfalg M, Raasi S, Pickart C, Fushman D.

Mol Cell. 2005 Jun 10;18(6):687-98.

14.

Molecular determinants of polyubiquitin linkage selection by an HECT ubiquitin ligase.

Wang M, Cheng D, Peng J, Pickart CM.

EMBO J. 2006 Apr 19;25(8):1710-9. Epub 2006 Apr 6.

15.

Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pH.

Eddins MJ, Varadan R, Fushman D, Pickart CM, Wolberger C.

J Mol Biol. 2007 Mar 16;367(1):204-11. Epub 2006 Dec 29.

PMID:
17240395
16.

Emerging roles for Lys11-linked polyubiquitin in cellular regulation.

Bremm A, Komander D.

Trends Biochem Sci. 2011 Jul;36(7):355-63. doi: 10.1016/j.tibs.2011.04.004. Epub 2011 Jun 7. Review.

PMID:
21641804
17.

The diversity of ubiquitin recognition: hot spots and varied specificity.

Winget JM, Mayor T.

Mol Cell. 2010 Jun 11;38(5):627-35. doi: 10.1016/j.molcel.2010.05.003. Review.

18.

Controlled synthesis of polyubiquitin chains.

Pickart CM, Raasi S.

Methods Enzymol. 2005;399:21-36.

PMID:
16338346
19.

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.

Christensen DE, Brzovic PS, Klevit RE.

Nat Struct Mol Biol. 2007 Oct;14(10):941-8. Epub 2007 Sep 16.

PMID:
17873885
20.

Allosteric activation of human glucokinase by free polyubiquitin chains and its ubiquitin-dependent cotranslational proteasomal degradation.

Bjørkhaug L, Molnes J, Søvik O, Njølstad PR, Flatmark T.

J Biol Chem. 2007 Aug 3;282(31):22757-64. Epub 2007 Jun 8.

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