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Items: 1 to 20 of 99

1.

Optimal sampling of rat liver tissue for toxicogenomic studies.

Foley JF, Collins JB, Umbach DM, Grissom S, Boorman GA, Heinloth AN.

Toxicol Pathol. 2006;34(6):795-801.

2.

Transcriptional profiling of the left and median liver lobes of male f344/n rats following exposure to acetaminophen.

Irwin RD, Parker JS, Lobenhofer EK, Burka LT, Blackshear PE, Vallant MK, Lebetkin EH, Gerken DF, Boorman GA.

Toxicol Pathol. 2005;33(1):111-7.

3.

Gene expression profile in liver of differing ages of rats after single oral administration of acetaminophen.

Morishita K, Mizukawa Y, Kasahara T, Okuyama M, Takashima K, Toritsuka N, Miyagishima T, Nagao T, Urushidani T.

J Toxicol Sci. 2006 Dec;31(5):491-507.

4.

Gene expression analysis offers unique advantages to histopathology in liver biopsy evaluations.

Heinloth AN, Boorman GA, Foley JF, Flagler ND, Paules RS.

Toxicol Pathol. 2007 Feb;35(2):276-83. Erratum in: Toxicol Pathol. 2007;35(6):850.

5.

Evaluation of DNA microarray results in the Toxicogenomics Project (TGP) consortium in Japan.

Noriyuki N, Igarashi Y, Ono A, Yamada H, Ohno Y, Urushidani T.

J Toxicol Sci. 2012;37(4):791-801.

6.

Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses.

Beyer RP, Fry RC, Lasarev MR, McConnachie LA, Meira LB, Palmer VS, Powell CL, Ross PK, Bammler TK, Bradford BU, Cranson AB, Cunningham ML, Fannin RD, Higgins GM, Hurban P, Kayton RJ, Kerr KF, Kosyk O, Lobenhofer EK, Sieber SO, Vliet PA, Weis BK, Wolfinger R, Woods CG, Freedman JH, Linney E, Kaufmann WK, Kavanagh TJ, Paules RS, Rusyn I, Samson LD, Spencer PS, Suk W, Tennant RJ, Zarbl H; Members of the Toxicogenomics Research Consortium.

Toxicol Sci. 2007 Sep;99(1):326-37. Epub 2007 Jun 11.

7.

Acute exposure to ozone exacerbates acetaminophen-induced liver injury in mice.

Aibo DI, Birmingham NP, Lewandowski R, Maddox JF, Roth RA, Ganey PE, Wagner JG, Harkema JR.

Toxicol Sci. 2010 May;115(1):267-85. doi: 10.1093/toxsci/kfq034. Epub 2010 Feb 1.

8.

Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel.

Harrill AH, Ross PK, Gatti DM, Threadgill DW, Rusyn I.

Toxicol Sci. 2009 Jul;110(1):235-43. doi: 10.1093/toxsci/kfp096. Epub 2009 May 6.

9.

Protective effects of diallyl sulfide on acetaminophen-induced toxicities.

Hu JJ, Yoo JS, Lin M, Wang EJ, Yang CS.

Food Chem Toxicol. 1996 Oct;34(10):963-9.

PMID:
9012771
10.

Gene expression in rat hearts following oral administration of a single hepatotoxic dose of acetaminophen.

Jin SM, Kil HR, Park K, Noh CI.

Yonsei Med J. 2012 Jan;53(1):172-80. doi: 10.3349/ymj.2012.53.1.172.

11.

Influence of acetaminophen vehicle on regulation of transporter gene expression during hepatotoxicity.

Aleksunes LM, Augustine LM, Cherrington NJ, Manautou JE.

J Toxicol Environ Health A. 2007 Nov;70(21):1870-2.

PMID:
17934960
12.

Toxicogenomic analysis of the particle dose- and size-response relationship of silica particles-induced toxicity in mice.

Lu X, Jin T, Jin Y, Wu L, Hu B, Tian Y, Fan X.

Nanotechnology. 2013 Jan 11;24(1):015106. doi: 10.1088/0957-4484/24/1/015106. Epub 2012 Dec 10.

PMID:
23221170
13.

Gene expression profiling of rat livers reveals indicators of potential adverse effects.

Heinloth AN, Irwin RD, Boorman GA, Nettesheim P, Fannin RD, Sieber SO, Snell ML, Tucker CJ, Li L, Travlos GS, Vansant G, Blackshear PE, Tennant RW, Cunningham ML, Paules RS.

Toxicol Sci. 2004 Jul;80(1):193-202. Epub 2004 Apr 14.

14.

Gene interaction network analysis suggests differences between high and low doses of acetaminophen.

Toyoshiba H, Sone H, Yamanaka T, Parham FM, Irwin RD, Boorman GA, Portier CJ.

Toxicol Appl Pharmacol. 2006 Sep 15;215(3):306-16. Epub 2006 May 15.

PMID:
16701773
15.

Effect of repeated administration with subtoxic doses of acetaminophen to rats on enterohepatic recirculation of a subsequent toxic dose.

Ghanem CI, Ruiz ML, Villanueva SS, Luquita M, Llesuy S, Catania VA, Bengochea LA, Mottino AD.

Biochem Pharmacol. 2009 May 15;77(10):1621-8. doi: 10.1016/j.bcp.2009.02.006. Epub 2009 Feb 23.

PMID:
19426699
16.

Parallelogram approach using rat-human in vitro and rat in vivo toxicogenomics predicts acetaminophen-induced hepatotoxicity in humans.

Kienhuis AS, van de Poll MC, Wortelboer H, van Herwijnen M, Gottschalk R, Dejong CH, Boorsma A, Paules RS, Kleinjans JC, Stierum RH, van Delft JH.

Toxicol Sci. 2009 Feb;107(2):544-52. doi: 10.1093/toxsci/kfn237. Epub 2008 Nov 12.

17.

Pentraxin 3 as a potential biomarker of acetaminophen-induced liver injury.

Yaman H, Cakir E, Akgul EO, Aydin I, Onguru O, Cayci T, Kurt YG, Agilli M, Aydin FN, Gulec M, Altinel O, Isbilir S, Ersoz N, Yasar M, Turker T, Bilgi C, Erbil KM.

Exp Toxicol Pathol. 2013 Jan;65(1-2):147-51. doi: 10.1016/j.etp.2011.07.003. Epub 2011 Aug 30.

PMID:
21880472
18.

The protective effects of ozone therapy in a rat model of acetaminophen-induced liver injury.

Gul H, Uysal B, Cakir E, Yaman H, Macit E, Yildirim AO, Eyi YE, Kaldirim U, Oztas E, Akgul EO, Cayci T, Ozler M, Topal T, Oter S, Korkmaz A, Toygar M, Demirbag S.

Environ Toxicol Pharmacol. 2012 Jul;34(1):81-6. doi: 10.1016/j.etap.2012.02.006. Epub 2012 Mar 3.

PMID:
22459800
19.

Effects of acetaminophen on hepatic gene expression in mice.

Jeong SY, Lim JS, Park HJ, Cho JW, Rana SV, Yoon S.

Physiol Chem Phys Med NMR. 2006;38(2):77-83.

PMID:
18472468
20.

Differential gene expression analysis of a known hepatotoxin, N-acetyl-p-amino-phenol (APAP) as compared to its non-toxic analog, N-acetyl-m-amino-phenol (AMAP) in mouse liver.

Priyadarsiny P, Khattar SK, Malik R, Udupa V, Seshaiah A, Rahman S, Shingatgeri VM, Bora RS, Saini KS.

J Toxicol Sci. 2008 May;33(2):163-73.

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