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Results: 1 to 20 of 171

1.

Effect of grapefruit juice on cytochrome P450 2A6 and nicotine renal clearance.

Hukkanen J, Jacob P 3rd, Benowitz NL.

Clin Pharmacol Ther. 2006 Nov;80(5):522-30.

PMID:
17112808
[PubMed - indexed for MEDLINE]
2.

CYP2A6 genotype and the metabolism and disposition kinetics of nicotine.

Benowitz NL, Swan GE, Jacob P 3rd, Lessov-Schlaggar CN, Tyndale RF.

Clin Pharmacol Ther. 2006 Nov;80(5):457-67.

PMID:
17112802
[PubMed - indexed for MEDLINE]
3.

Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity.

Dempsey D, Tutka P, Jacob P 3rd, Allen F, Schoedel K, Tyndale RF, Benowitz NL.

Clin Pharmacol Ther. 2004 Jul;76(1):64-72.

PMID:
15229465
[PubMed - indexed for MEDLINE]
4.

Time course of recovery of cytochrome p450 3A function after single doses of grapefruit juice.

Greenblatt DJ, von Moltke LL, Harmatz JS, Chen G, Weemhoff JL, Jen C, Kelley CJ, LeDuc BW, Zinny MA.

Clin Pharmacol Ther. 2003 Aug;74(2):121-9.

PMID:
12891222
[PubMed - indexed for MEDLINE]
5.

Influence of menstrual cycle on cytochrome P450 2A6 activity and cardiovascular effects of nicotine.

Hukkanen J, Gourlay SG, Kenkare S, Benowitz NL.

Clin Pharmacol Ther. 2005 Mar;77(3):159-69.

PMID:
15735610
[PubMed - indexed for MEDLINE]
6.

Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice.

Bailey DG, Dresser GK, Bend JR.

Clin Pharmacol Ther. 2003 Jun;73(6):529-37.

PMID:
12811362
[PubMed - indexed for MEDLINE]
7.

Influence of grapefruit juice on cisapride pharmacokinetics.

Gross AS, Goh YD, Addison RS, Shenfield GM.

Clin Pharmacol Ther. 1999 Apr;65(4):395-401.

PMID:
10223776
[PubMed - indexed for MEDLINE]
8.

Population pharmacokinetics of nicotine and its metabolites I. Model development.

Levi M, Dempsey DA, Benowitz NL, Sheiner LB.

J Pharmacokinet Pharmacodyn. 2007 Feb;34(1):5-21. Epub 2007 Jan 6.

PMID:
17206524
[PubMed - indexed for MEDLINE]
9.

Stereoselective pharmacokinetics of cisapride in healthy volunteers and the effect of repeated administration of grapefruit juice.

Desta Z, Kivistö KT, Lilja JJ, Backman JT, Soukhova N, Neuvonen PJ, Flockhart DA.

Br J Clin Pharmacol. 2001 Oct;52(4):399-407.

PMID:
11678783
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Grapefruit juice enhances the bioavailability of the HIV protease inhibitor saquinavir in man.

Kupferschmidt HH, Fattinger KE, Ha HR, Follath F, Krähenbühl S.

Br J Clin Pharmacol. 1998 Apr;45(4):355-9.

PMID:
9578182
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Identification of novel CYP2A6*1B variants: the CYP2A6*1B allele is associated with faster in vivo nicotine metabolism.

Mwenifumbo JC, Lessov-Schlaggar CN, Zhou Q, Krasnow RE, Swan GE, Benowitz NL, Tyndale RF.

Clin Pharmacol Ther. 2008 Jan;83(1):115-21. Epub 2007 May 23.

PMID:
17522595
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Effects of grapefruit juice on the pharmacokinetics of the enantiomers of methadone.

Benmebarek M, Devaud C, Gex-Fabry M, Powell Golay K, Brogli C, Baumann P, Gravier B, Eap CB.

Clin Pharmacol Ther. 2004 Jul;76(1):55-63.

PMID:
15229464
[PubMed - indexed for MEDLINE]
13.

Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: comparison with ritonavir.

Culm-Merdek KE, von Moltke LL, Gan L, Horan KA, Reynolds R, Harmatz JS, Court MH, Greenblatt DJ.

Clin Pharmacol Ther. 2006 Mar;79(3):243-54. Epub 2006 Feb 7.

PMID:
16513448
[PubMed - indexed for MEDLINE]
14.

Grapefruit juice substantially increases plasma concentrations of buspirone.

Lilja JJ, Kivistö KT, Backman JT, Lamberg TS, Neuvonen PJ.

Clin Pharmacol Ther. 1998 Dec;64(6):655-60.

PMID:
9871430
[PubMed - indexed for MEDLINE]
15.

Nicotine metabolism and elimination kinetics in newborns.

Dempsey D, Jacob P 3rd, Benowitz NL.

Clin Pharmacol Ther. 2000 May;67(5):458-65.

PMID:
10824624
[PubMed - indexed for MEDLINE]
16.

The effect of methoxsalen on nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism in vivo.

Sellers EM, Ramamoorthy Y, Zeman MV, Djordjevic MV, Tyndale RF.

Nicotine Tob Res. 2003 Dec;5(6):891-9.

PMID:
14668073
[PubMed - indexed for MEDLINE]
17.

Relationship between interindividual differences in nicotine metabolism and CYP2A6 genetic polymorphism in humans.

Nakajima M, Kwon JT, Tanaka N, Zenta T, Yamamoto Y, Yamamoto H, Yamazaki H, Yamamoto T, Kuroiwa Y, Yokoi T.

Clin Pharmacol Ther. 2001 Jan;69(1):72-8.

PMID:
11180041
[PubMed - indexed for MEDLINE]
18.

Coadministration of grapefruit juice increases systemic exposure of diltiazem in healthy volunteers.

Christensen H, Asberg A, Holmboe AB, Berg KJ.

Eur J Clin Pharmacol. 2002 Nov;58(8):515-20. Epub 2002 Oct 16.

PMID:
12451428
[PubMed - indexed for MEDLINE]
19.

Effects of grapefruit juice on intestinal P-glycoprotein: evaluation using digoxin in humans.

Parker RB, Yates CR, Soberman JE, Laizure SC.

Pharmacotherapy. 2003 Aug;23(8):979-87.

PMID:
12921244
[PubMed - indexed for MEDLINE]
20.

S-ketamine concentrations are greatly increased by grapefruit juice.

Peltoniemi MA, Saari TI, Hagelberg NM, Laine K, Neuvonen PJ, Olkkola KT.

Eur J Clin Pharmacol. 2012 Jun;68(6):979-86. doi: 10.1007/s00228-012-1214-9.

PMID:
22286159
[PubMed - indexed for MEDLINE]

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