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Items: 1 to 20 of 102


Conditional deletion of beta1 integrins in the intestinal epithelium causes a loss of Hedgehog expression, intestinal hyperplasia, and early postnatal lethality.

Jones RG, Li X, Gray PD, Kuang J, Clayton F, Samowitz WS, Madison BB, Gumucio DL, Kuwada SK.

J Cell Biol. 2006 Nov 6;175(3):505-14.


Regulation of sonic hedgehog expression by integrin β1 and epidermal growth factor receptor in intestinal epithelium.

Xu C, Li X, Topham MK, Kuwada SK.

IUBMB Life. 2014 Oct;66(10):694-703. doi: 10.1002/iub.1319. Epub 2014 Oct 30.


Phases of canonical Wnt signaling during the development of mouse intestinal epithelium.

Kim BM, Mao J, Taketo MM, Shivdasani RA.

Gastroenterology. 2007 Aug;133(2):529-38. Epub 2007 May 3.


Cooperation between HNF-1alpha, Cdx2, and GATA-4 in initiating an enterocytic differentiation program in a normal human intestinal epithelial progenitor cell line.

Benoit YD, Paré F, Francoeur C, Jean D, Tremblay E, Boudreau F, Escaffit F, Beaulieu JF.

Am J Physiol Gastrointest Liver Physiol. 2010 Apr;298(4):G504-17. doi: 10.1152/ajpgi.00265.2009. Epub 2010 Feb 4.


Ablation of beta1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation.

Naylor MJ, Li N, Cheung J, Lowe ET, Lambert E, Marlow R, Wang P, Schatzmann F, Wintermantel T, Schüetz G, Clarke AR, Mueller U, Hynes NE, Streuli CH.

J Cell Biol. 2005 Nov 21;171(4):717-28.


Hepatocyte nuclear factor 4alpha contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation.

Babeu JP, Darsigny M, Lussier CR, Boudreau F.

Am J Physiol Gastrointest Liver Physiol. 2009 Jul;297(1):G124-34. doi: 10.1152/ajpgi.90690.2008. Epub 2009 Apr 23.


Depletion of the colonic epithelial precursor cell compartment upon conditional activation of the hedgehog pathway.

van Dop WA, Uhmann A, Wijgerde M, Sleddens-Linkels E, Heijmans J, Offerhaus GJ, van den Bergh Weerman MA, Boeckxstaens GE, Hommes DW, Hardwick JC, Hahn H, van den Brink GR.

Gastroenterology. 2009 Jun;136(7):2195-2203.e1-7. doi: 10.1053/j.gastro.2009.02.068. Epub 2009 Mar 6.


Hedgehog signaling controls homeostasis of adult intestinal smooth muscle.

Zacharias WJ, Madison BB, Kretovich KE, Walton KD, Richards N, Udager AM, Li X, Gumucio DL.

Dev Biol. 2011 Jul 1;355(1):152-62. doi: 10.1016/j.ydbio.2011.04.025. Epub 2011 Apr 28.


Epithelial hedgehog signals pattern the intestinal crypt-villus axis.

Madison BB, Braunstein K, Kuizon E, Portman K, Qiao XT, Gumucio DL.

Development. 2005 Jan;132(2):279-89. Epub 2004 Dec 8.


Specific β-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells.

Jeanes AI, Wang P, Moreno-Layseca P, Paul N, Cheung J, Tsang R, Akhtar N, Foster FM, Brennan K, Streuli CH.

J Biol Chem. 2012 Jul 13;287(29):24103-12. doi: 10.1074/jbc.M112.360834. Epub 2012 Apr 16.


Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium.

Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA.

Dev Biol. 2013 Mar 15;375(2):128-39. doi: 10.1016/j.ydbio.2012.12.010. Epub 2012 Dec 22.


Fak/Src signaling in human intestinal epithelial cell survival and anoikis: differentiation state-specific uncoupling with the PI3-K/Akt-1 and MEK/Erk pathways.

Bouchard V, Demers MJ, Thibodeau S, Laquerre V, Fujita N, Tsuruo T, Beaulieu JF, Gauthier R, Vézina A, Villeneuve L, Vachon PH.

J Cell Physiol. 2007 Sep;212(3):717-28.


Indian hedgehog regulates intestinal stem cell fate through epithelial-mesenchymal interactions during development.

Kosinski C, Stange DE, Xu C, Chan AS, Ho C, Yuen ST, Mifflin RC, Powell DW, Clevers H, Leung SY, Chen X.

Gastroenterology. 2010 Sep;139(3):893-903. doi: 10.1053/j.gastro.2010.06.014. Epub 2010 Jun 11.


Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia.

Moraes RC, Zhang X, Harrington N, Fung JY, Wu MF, Hilsenbeck SG, Allred DC, Lewis MT.

Development. 2007 Mar;134(6):1231-42. Epub 2007 Feb 7.


Disruption of hedgehog signaling reveals a novel role in intestinal morphogenesis and intestinal-specific lipid metabolism in mice.

Wang LC, Nassir F, Liu ZY, Ling L, Kuo F, Crowell T, Olson D, Davidson NO, Burkly LC.

Gastroenterology. 2002 Feb;122(2):469-82.


Butyrate-treated colonic Caco-2 cells exhibit defective integrin-mediated signaling together with increased apoptosis and differentiation.

Lévy P, Robin H, Bertrand F, Kornprobst M, Capeau J.

J Cell Physiol. 2003 Dec;197(3):336-47.


Hedgehog signaling plays roles in epithelial cell proliferation in neonatal mouse uterus and vagina.

Nakajima T, Iguchi T, Sato T.

Cell Tissue Res. 2012 Apr;348(1):239-47. doi: 10.1007/s00441-012-1350-7. Epub 2012 Mar 3.


Transforming growth factor-{beta}1 induces Smad3-dependent {beta}1 integrin gene expression in epithelial-to-mesenchymal transition during chronic tubulointerstitial fibrosis.

Yeh YC, Wei WC, Wang YK, Lin SC, Sung JM, Tang MJ.

Am J Pathol. 2010 Oct;177(4):1743-54. doi: 10.2353/ajpath.2010.091183. Epub 2010 Aug 13.


Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype.

Simirskii VN, Wang Y, Duncan MK.

Dev Biol. 2007 Jun 15;306(2):658-68. Epub 2007 Apr 12.

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