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Results: 1 to 20 of 198

1.

Spatially regulated ubiquitin ligation by an ER/nuclear membrane ligase.

Deng M, Hochstrasser M.

Nature. 2006 Oct 19;443(7113):827-31.

PMID:
17051211
[PubMed - indexed for MEDLINE]
2.

A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation.

Swanson R, Locher M, Hochstrasser M.

Genes Dev. 2001 Oct 15;15(20):2660-74.

PMID:
11641273
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Membrane and soluble substrates of the Doa10 ubiquitin ligase are degraded by distinct pathways.

Ravid T, Kreft SG, Hochstrasser M.

EMBO J. 2006 Feb 8;25(3):533-43. Epub 2006 Jan 26.

PMID:
16437165
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI).

Kreft SG, Wang L, Hochstrasser M.

J Biol Chem. 2006 Feb 24;281(8):4646-53. Epub 2005 Dec 22.

PMID:
16373356
[PubMed - indexed for MEDLINE]
Free Article
5.

Ubx2 links the Cdc48 complex to ER-associated protein degradation.

Neuber O, Jarosch E, Volkwein C, Walter J, Sommer T.

Nat Cell Biol. 2005 Oct;7(10):993-8. Epub 2005 Sep 18.

PMID:
16179953
[PubMed - indexed for MEDLINE]
Free Article
6.

Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation.

Schuberth C, Buchberger A.

Nat Cell Biol. 2005 Oct;7(10):999-1006. Epub 2005 Sep 18.

PMID:
16179952
[PubMed - indexed for MEDLINE]
Free Article
7.

An unusual transmembrane helix in the endoplasmic reticulum ubiquitin ligase Doa10 modulates degradation of its cognate E2 enzyme.

Kreft SG, Hochstrasser M.

J Biol Chem. 2011 Jun 10;286(23):20163-74. doi: 10.1074/jbc.M110.196360. Epub 2011 Apr 5.

PMID:
21467040
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase.

Rubenstein EM, Kreft SG, Greenblatt W, Swanson R, Hochstrasser M.

J Cell Biol. 2012 Jun 11;197(6):761-73. doi: 10.1083/jcb.201203061.

PMID:
22689655
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum.

Kikkert M, Doolman R, Dai M, Avner R, Hassink G, van Voorden S, Thanedar S, Roitelman J, Chau V, Wiertz E.

J Biol Chem. 2004 Jan 30;279(5):3525-34. Epub 2003 Oct 30.

PMID:
14593114
[PubMed - indexed for MEDLINE]
Free Article
10.

Ubiquitin ligase Hul5 is required for fragment-specific substrate degradation in endoplasmic reticulum-associated degradation.

Kohlmann S, Schäfer A, Wolf DH.

J Biol Chem. 2008 Jun 13;283(24):16374-83. doi: 10.1074/jbc.M801702200. Epub 2008 Apr 24.

PMID:
18436532
[PubMed - indexed for MEDLINE]
Free Article
11.

The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment.

Gauss R, Sommer T, Jarosch E.

EMBO J. 2006 May 3;25(9):1827-35. Epub 2006 Apr 13.

PMID:
16619026
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Dfm1 forms distinct complexes with Cdc48 and the ER ubiquitin ligases and is required for ERAD.

Stolz A, Schweizer RS, Schäfer A, Wolf DH.

Traffic. 2010 Oct;11(10):1363-9. doi: 10.1111/j.1600-0854.2010.01093.x.

PMID:
20579315
[PubMed - indexed for MEDLINE]
13.

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins.

Carvalho P, Goder V, Rapoport TA.

Cell. 2006 Jul 28;126(2):361-73.

PMID:
16873066
[PubMed - indexed for MEDLINE]
Free Article
14.

Previously unknown role for the ubiquitin ligase Ubr1 in endoplasmic reticulum-associated protein degradation.

Stolz A, Besser S, Hottmann H, Wolf DH.

Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15271-6. doi: 10.1073/pnas.1304928110. Epub 2013 Aug 29.

PMID:
23988329
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Hsp70 targets a cytoplasmic quality control substrate to the San1p ubiquitin ligase.

Guerriero CJ, Weiberth KF, Brodsky JL.

J Biol Chem. 2013 Jun 21;288(25):18506-20. doi: 10.1074/jbc.M113.475905. Epub 2013 May 7.

PMID:
23653356
[PubMed - indexed for MEDLINE]
Free PMC Article
16.
17.

An HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transport.

Haynes CM, Caldwell S, Cooper AA.

J Cell Biol. 2002 Jul 8;158(1):91-101. Epub 2002 Jul 8.

PMID:
12105183
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Ubiquitin chain elongation enzyme Ufd2 regulates a subset of Doa10 substrates.

Liu C, van Dyk D, Xu P, Choe V, Pan H, Peng J, Andrews B, Rao H.

J Biol Chem. 2010 Apr 2;285(14):10265-72. doi: 10.1074/jbc.M110.110551. Epub 2010 Feb 16.

PMID:
20159987
[PubMed - indexed for MEDLINE]
Free PMC Article
19.
20.

Biosynthetic mode can determine the mechanism of protein quality control.

Prasad R, Kawaguchi S, Ng DT.

Biochem Biophys Res Commun. 2012 Aug 31;425(3):689-95. doi: 10.1016/j.bbrc.2012.07.080. Epub 2012 Jul 25.

PMID:
22842567
[PubMed - indexed for MEDLINE]

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