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Results: 1 to 20 of 77

1.

Minimizing the risk of reporting false positives in large-scale RNAi screens.

Echeverri CJ, Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, Hahn WC, Jackson AL, Kiger A, Linsley PS, Lum L, Ma Y, Mathey-Prévôt B, Root DE, Sabatini DM, Taipale J, Perrimon N, Bernards R.

Nat Methods. 2006 Oct;3(10):777-9.

PMID:
16990807
[PubMed - indexed for MEDLINE]
2.

An effective method for controlling false discovery and false nondiscovery rates in genome-scale RNAi screens.

Zhang XD.

J Biomol Screen. 2010 Oct;15(9):1116-22. doi: 10.1177/1087057110381783. Epub 2010 Sep 20.

PMID:
20855561
[PubMed - indexed for MEDLINE]
3.

Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays.

Kulkarni MM, Booker M, Silver SJ, Friedman A, Hong P, Perrimon N, Mathey-Prevot B.

Nat Methods. 2006 Oct;3(10):833-8.

PMID:
16964256
[PubMed - indexed for MEDLINE]
4.

The use of SSMD-based false discovery and false nondiscovery rates in genome-scale RNAi screens.

Zhang XD, Lacson R, Yang R, Marine SD, McCampbell A, Toolan DM, Hare TR, Kajdas J, Berger JP, Holder DJ, Heyse JF, Ferrer M.

J Biomol Screen. 2010 Oct;15(9):1123-31. doi: 10.1177/1087057110381919. Epub 2010 Sep 17.

PMID:
20852024
[PubMed - indexed for MEDLINE]
5.

A protein network-guided screen for cell cycle regulators in Drosophila.

Guest ST, Yu J, Liu D, Hines JA, Kashat MA, Finley RL Jr.

BMC Syst Biol. 2011 May 6;5:65. doi: 10.1186/1752-0509-5-65.

PMID:
21548953
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Matter arising: off-targets and genome-scale RNAi screens in Drosophila.

Perrimon N, Mathey-Prevot B.

Fly (Austin). 2007 Jan-Feb;1(1):1-5.

PMID:
18705022
[PubMed - indexed for MEDLINE]
Free Article
7.

A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila.

Wang L, Tu Z, Sun F.

BMC Genomics. 2009 May 12;10:220. doi: 10.1186/1471-2164-10-220.

PMID:
19435510
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

RNAi screening: new approaches, understandings, and organisms.

Mohr SE, Perrimon N.

Wiley Interdiscip Rev RNA. 2012 Mar-Apr;3(2):145-58. doi: 10.1002/wrna.110. Epub 2011 Sep 22. Review.

PMID:
21953743
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Parallel RNAi screens across different cell lines identify generic and cell type-specific regulators of actin organization and cell morphology.

Liu T, Sims D, Baum B.

Genome Biol. 2009;10(3):R26. doi: 10.1186/gb-2009-10-3-r26. Epub 2009 Mar 5.

PMID:
19265526
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Error rates and powers in genome-scale RNAi screens.

Zhang XD, Marine SD, Ferrer M.

J Biomol Screen. 2009 Mar;14(3):230-8. doi: 10.1177/1087057109331475. Epub 2009 Feb 11.

PMID:
19211781
[PubMed - indexed for MEDLINE]
11.

High-throughput screening by RNA interference: control of two distinct types of variance.

Stone DJ, Marine S, Majercak J, Ray WJ, Espeseth A, Simon A, Ferrer M.

Cell Cycle. 2007 Apr 15;6(8):898-901. Epub 2007 Apr 22.

PMID:
17438372
[PubMed - indexed for MEDLINE]
Free Article
12.

A probability-based approach for the analysis of large-scale RNAi screens.

König R, Chiang CY, Tu BP, Yan SF, DeJesus PD, Romero A, Bergauer T, Orth A, Krueger U, Zhou Y, Chanda SK.

Nat Methods. 2007 Oct;4(10):847-9. Epub 2007 Sep 9.

PMID:
17828270
[PubMed - indexed for MEDLINE]
13.

False negative rates in Drosophila cell-based RNAi screens: a case study.

Booker M, Samsonova AA, Kwon Y, Flockhart I, Mohr SE, Perrimon N.

BMC Genomics. 2011 Jan 20;12:50. doi: 10.1186/1471-2164-12-50.

PMID:
21251254
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

RNA interference in mammals: behind the screen.

Campeau E, Gobeil S.

Brief Funct Genomics. 2011 Jul;10(4):215-26. doi: 10.1093/bfgp/elr018. Review.

PMID:
21791555
[PubMed - indexed for MEDLINE]
15.

A novel method for tissue-specific RNAi rescue in Drosophila.

Schulz JG, David G, Hassan BA.

Nucleic Acids Res. 2009 Jul;37(13):e93. doi: 10.1093/nar/gkp450. Epub 2009 May 29.

PMID:
19483100
[PubMed - indexed for MEDLINE]
Free PMC Article
16.
17.

Vector-based RNAi approaches for stable, inducible and genome-wide screens.

Fewell GD, Schmitt K.

Drug Discov Today. 2006 Nov;11(21-22):975-82. Epub 2006 Sep 26. Review.

PMID:
17055406
[PubMed - indexed for MEDLINE]
18.

Limited agreement of independent RNAi screens for virus-required host genes owes more to false-negative than false-positive factors.

Hao L, He Q, Wang Z, Craven M, Newton MA, Ahlquist P.

PLoS Comput Biol. 2013;9(9):e1003235. doi: 10.1371/journal.pcbi.1003235. Epub 2013 Sep 19.

PMID:
24068911
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.

Kirkland D, Pfuhler S, Tweats D, Aardema M, Corvi R, Darroudi F, Elhajouji A, Glatt H, Hastwell P, Hayashi M, Kasper P, Kirchner S, Lynch A, Marzin D, Maurici D, Meunier JR, Müller L, Nohynek G, Parry J, Parry E, Thybaud V, Tice R, van Benthem J, Vanparys P, White P.

Mutat Res. 2007 Mar 30;628(1):31-55. Epub 2007 Jan 13.

PMID:
17293159
[PubMed - indexed for MEDLINE]
20.

Opening a new can of worms: a large-scale RNAi screen in planarians.

Newmark PA.

Dev Cell. 2005 May;8(5):623-4.

PMID:
15866153
[PubMed - indexed for MEDLINE]
Free Article

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