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Items: 1 to 20 of 134

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Murine Lyme arthritis development mediated by p38 mitogen-activated protein kinase activity.

Anguita J, Barthold SW, Persinski R, Hedrick MN, Huy CA, Davis RJ, Flavell RA, Fikrig E.

J Immunol. 2002 Jun 15;168(12):6352-7.

3.

Selective requirement of p38alpha MAPK in cytokine-dependent, but not antigen receptor-dependent, Th1 responses.

Berenson LS, Yang J, Sleckman BP, Murphy TL, Murphy KM.

J Immunol. 2006 Apr 15;176(8):4616-21.

4.

Macrophage p38 mitogen-activated protein kinase activity regulates invariant natural killer T-cell responses during Borrelia burgdorferi infection.

Hawley K, Navasa N, Olson CM Jr, Bates TC, Garg R, Hedrick MN, Conze D, Rincón M, Anguita J.

J Infect Dis. 2012 Jul 15;206(2):283-91. doi: 10.1093/infdis/jis332. Epub 2012 May 2.

5.

Regulation and phenotype of an innate Th1 cell: role of cytokines and the p38 kinase pathway.

Yu JJ, Tripp CS, Russell JH.

J Immunol. 2003 Dec 1;171(11):6112-8.

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Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice.

Lu HT, Yang DD, Wysk M, Gatti E, Mellman I, Davis RJ, Flavell RA.

EMBO J. 1999 Apr 1;18(7):1845-57.

10.

Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway.

Rincón M, Enslen H, Raingeaud J, Recht M, Zapton T, Su MS, Penix LA, Davis RJ, Flavell RA.

EMBO J. 1998 May 15;17(10):2817-29.

12.

GADD45gamma mediates the activation of the p38 and JNK MAP kinase pathways and cytokine production in effector TH1 cells.

Lu B, Yu H, Chow C, Li B, Zheng W, Davis RJ, Flavell RA.

Immunity. 2001 May;14(5):583-90.

13.

MEKK3 regulates IFN-gamma production in T cells through the Rac1/2-dependent MAPK cascades.

Wang X, Zhang F, Chen F, Liu D, Zheng Y, Zhang Y, Dong C, Su B.

J Immunol. 2011 May 15;186(10):5791-800. doi: 10.4049/jimmunol.1002127. Epub 2011 Apr 6.

14.

IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production.

Yang J, Zhu H, Murphy TL, Ouyang W, Murphy KM.

Nat Immunol. 2001 Feb;2(2):157-64.

PMID:
11175814
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Weak TCR stimulation induces a calcium signal that triggers IL-4 synthesis, stronger TCR stimulation induces MAP kinases that control IFN-gamma production.

Badou A, Savignac M, Moreau M, Leclerc C, Foucras G, Cassar G, Paulet P, Lagrange D, Druet P, Guéry JC, Pelletier L.

Eur J Immunol. 2001 Aug;31(8):2487-96.

17.

Differential regulation of T cell receptor-mediated Th1 cell IFN-gamma production and proliferation by divergent cAMP-mediated redox pathways.

Cochrane R, Clark RB, Huang CK, Cone RE.

J Interferon Cytokine Res. 2001 Oct;21(10):797-807.

PMID:
11710991
18.

STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation.

Morinobu A, Gadina M, Strober W, Visconti R, Fornace A, Montagna C, Feldman GM, Nishikomori R, O'Shea JJ.

Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12281-6. Epub 2002 Sep 4.

19.

Borrelia burgdorferi-induced inflammation facilitates spirochete adaptation and variable major protein-like sequence locus recombination.

Anguita J, Thomas V, Samanta S, Persinski R, Hernanz C, Barthold SW, Fikrig E.

J Immunol. 2001 Sep 15;167(6):3383-90.

20.

Genetic disruption of p38alpha Tyr323 phosphorylation prevents T-cell receptor-mediated p38alpha activation and impairs interferon-gamma production.

Jirmanova L, Sarma DN, Jankovic D, Mittelstadt PR, Ashwell JD.

Blood. 2009 Mar 5;113(10):2229-37. doi: 10.1182/blood-2008-04-153304. Epub 2008 Nov 14.

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