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Results: 1 to 20 of 104

1.

A mouse model for the molecular characterization of brca1-associated ovarian carcinoma.

Xing D, Orsulic S.

Cancer Res. 2006 Sep 15;66(18):8949-53.

PMID:
16982732
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Conditional inactivation of Brca1, p53 and Rb in mouse ovaries results in the development of leiomyosarcomas.

Clark-Knowles KV, Senterman MK, Collins O, Vanderhyden BC.

PLoS One. 2009 Dec 31;4(12):e8534. doi: 10.1371/journal.pone.0008534.

PMID:
20046869
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes.

Clark-Knowles KV, Garson K, Jonkers J, Vanderhyden BC.

Exp Cell Res. 2007 Jan 1;313(1):133-45. Epub 2006 Oct 3.

PMID:
17070800
[PubMed - indexed for MEDLINE]
4.

Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo.

Mullany LK, Fan HY, Liu Z, White LD, Marshall A, Gunaratne P, Anderson ML, Creighton CJ, Xin L, Deavers M, Wong KK, Richards JS.

Oncogene. 2011 Aug 11;30(32):3522-36. doi: 10.1038/onc.2011.70. Epub 2011 Mar 21.

PMID:
21423204
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

BRCA1-associated epigenetic regulation of p73 mediates an effector pathway for chemosensitivity in ovarian carcinoma.

Ibrahim N, He L, Leong CO, Xing D, Karlan BY, Swisher EM, Rueda BR, Orsulic S, Ellisen LW.

Cancer Res. 2010 Sep 15;70(18):7155-65. doi: 10.1158/0008-5472.CAN-10-0668. Epub 2010 Aug 31.

PMID:
20807817
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Growth retardation, DNA repair defects, and lack of spermatogenesis in BRCA1-deficient mice.

Cressman VL, Backlund DC, Avrutskaya AV, Leadon SA, Godfrey V, Koller BH.

Mol Cell Biol. 1999 Oct;19(10):7061-75. Partial retraction in: Cressman VL, Backlund DC, Avrutskaya AV, Leadon SA, Godfrey V, Koller BH. Mol Cell Biol. 2006 Dec;26(24):9571.

PMID:
10490643
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Conditional knockout of brca1/2 and p53 in mouse ovarian surface epithelium: do they play a role in ovarian carcinogenesis?

Kim KY, Park DW, Jeung EB, Choi KC.

J Vet Sci. 2010 Dec;11(4):291-7.

PMID:
21113097
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

BRCA1 and p53 protein expression in cultured ovarian surface epithelial cells derived from women with and without a BRCA1 germline mutation.

Piek JM, Dorsman JC, Massuger LF, Ansink AC, Weegenaar J, Shvarts A, Kenemans P, Verheijen RH.

Arch Gynecol Obstet. 2006 Oct;274(6):327-31. Epub 2006 Jul 7.

PMID:
16826413
[PubMed - indexed for MEDLINE]
9.

A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development.

Sherman-Baust CA, Kuhn E, Valle BL, Shih IeM, Kurman RJ, Wang TL, Amano T, Ko MS, Miyoshi I, Araki Y, Lehrmann E, Zhang Y, Becker KG, Morin PJ.

J Pathol. 2014 Jul;233(3):228-37. doi: 10.1002/path.4353.

PMID:
24652535
[PubMed - indexed for MEDLINE]
10.

Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes.

Sasaki R, Narisawa-Saito M, Yugawa T, Fujita M, Tashiro H, Katabuchi H, Kiyono T.

Carcinogenesis. 2009 Mar;30(3):423-31. doi: 10.1093/carcin/bgp007. Epub 2009 Jan 6.

PMID:
19126650
[PubMed - indexed for MEDLINE]
Free Article
11.

Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53.

Quinn BA, Brake T, Hua X, Baxter-Jones K, Litwin S, Ellenson LH, Connolly DC.

PLoS One. 2009 Dec 31;4(12):e8404. doi: 10.1371/journal.pone.0008404.

PMID:
20046879
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The effect of loss of Brca1 on the sensitivity to anticancer agents in p53-deficient cells.

Fedier A, Steiner RA, Schwarz VA, Lenherr L, Haller U, Fink D.

Int J Oncol. 2003 May;22(5):1169-73.

PMID:
12684687
[PubMed - indexed for MEDLINE]
13.

Induction of ovarian cancer by defined multiple genetic changes in a mouse model system.

Orsulic S, Li Y, Soslow RA, Vitale-Cross LA, Gutkind JS, Varmus HE.

Cancer Cell. 2002 Feb;1(1):53-62.

PMID:
12086888
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer.

Szabova L, Yin C, Bupp S, Guerin TM, Schlomer JJ, Householder DB, Baran ML, Yi M, Song Y, Sun W, McDunn JE, Martin PL, Van Dyke T, Difilippantonio S.

Cancer Res. 2012 Aug 15;72(16):4141-53. doi: 10.1158/0008-5472.CAN-11-3834. Epub 2012 May 22.

PMID:
22617326
[PubMed - indexed for MEDLINE]
Free PMC Article
15.
16.

Proteome changes in ovarian epithelial cells derived from women with BRCA1 mutations and family histories of cancer.

Smith-Beckerman DM, Fung KW, Williams KE, Auersperg N, Godwin AK, Burlingame AL.

Mol Cell Proteomics. 2005 Feb;4(2):156-68. Epub 2004 Dec 9.

PMID:
15591324
[PubMed - indexed for MEDLINE]
Free Article
17.

Functional characterization of a novel BRCA1-null ovarian cancer cell line in response to ionizing radiation.

DelloRusso C, Welcsh PL, Wang W, Garcia RL, King MC, Swisher EM.

Mol Cancer Res. 2007 Jan;5(1):35-45.

PMID:
17259345
[PubMed - indexed for MEDLINE]
Free Article
18.

Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.

Xu X, Qiao W, Linke SP, Cao L, Li WM, Furth PA, Harris CC, Deng CX.

Nat Genet. 2001 Jul;28(3):266-71.

PMID:
11431698
[PubMed - indexed for MEDLINE]
19.
20.

Molecular requirements for transformation of fallopian tube epithelial cells into serous carcinoma.

Jazaeri AA, Bryant JL, Park H, Li H, Dahiya N, Stoler MH, Ferriss JS, Dutta A.

Neoplasia. 2011 Oct;13(10):899-911.

PMID:
22028616
[PubMed - indexed for MEDLINE]
Free PMC Article

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