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Results: 1 to 20 of 108

1.

Control of phospholipid synthesis by phosphorylation of the yeast lipin Pah1p/Smp2p Mg2+-dependent phosphatidate phosphatase.

O'Hara L, Han GS, Peak-Chew S, Grimsey N, Carman GM, Siniossoglou S.

J Biol Chem. 2006 Nov 10;281(45):34537-48. Epub 2006 Sep 12.

PMID:
16968695
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Pho85p-Pho80p phosphorylation of yeast Pah1p phosphatidate phosphatase regulates its activity, location, abundance, and function in lipid metabolism.

Choi HS, Su WM, Han GS, Plote D, Xu Z, Carman GM.

J Biol Chem. 2012 Mar 30;287(14):11290-301. doi: 10.1074/jbc.M112.346023. Epub 2012 Feb 9.

PMID:
22334681
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Phosphorylation of phosphatidate phosphatase regulates its membrane association and physiological functions in Saccharomyces cerevisiae: identification of SER(602), THR(723), AND SER(744) as the sites phosphorylated by CDC28 (CDK1)-encoded cyclin-dependent kinase.

Choi HS, Su WM, Morgan JM, Han GS, Xu Z, Karanasios E, Siniossoglou S, Carman GM.

J Biol Chem. 2011 Jan 14;286(2):1486-98. doi: 10.1074/jbc.M110.155598. Epub 2010 Nov 16.

PMID:
21081492
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Regulation of lipid droplet and membrane biogenesis by the acidic tail of the phosphatidate phosphatase Pah1p.

Karanasios E, Barbosa AD, Sembongi H, Mari M, Han GS, Reggiori F, Carman GM, Siniossoglou S.

Mol Biol Cell. 2013 Jul;24(13):2124-33. doi: 10.1091/mbc.E13-01-0021. Epub 2013 May 8.

PMID:
23657815
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Cross-talk phosphorylations by protein kinase C and Pho85p-Pho80p protein kinase regulate Pah1p phosphatidate phosphatase abundance in Saccharomyces cerevisiae.

Su WM, Han GS, Carman GM.

J Biol Chem. 2014 Jul 4;289(27):18818-30. doi: 10.1074/jbc.M114.581462. Epub 2014 May 29.

PMID:
24876385
[PubMed - indexed for MEDLINE]
6.

PAH1-encoded phosphatidate phosphatase plays a role in the growth phase- and inositol-mediated regulation of lipid synthesis in Saccharomyces cerevisiae.

Pascual F, Soto-Cardalda A, Carman GM.

J Biol Chem. 2013 Dec 13;288(50):35781-92. doi: 10.1074/jbc.M113.525766. Epub 2013 Nov 6.

PMID:
24196957
[PubMed - indexed for MEDLINE]
7.

The Saccharomyces cerevisiae Lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme.

Han GS, Wu WI, Carman GM.

J Biol Chem. 2006 Apr 7;281(14):9210-8. Epub 2006 Feb 8.

PMID:
16467296
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Yeast Pah1p phosphatidate phosphatase is regulated by proteasome-mediated degradation.

Pascual F, Hsieh LS, Soto-Cardalda A, Carman GM.

J Biol Chem. 2014 Apr 4;289(14):9811-22. doi: 10.1074/jbc.M114.550103. Epub 2014 Feb 21.

PMID:
24563465
[PubMed - indexed for MEDLINE]
9.
10.

Phosphatidate phosphatase, a key regulator of lipid homeostasis.

Pascual F, Carman GM.

Biochim Biophys Acta. 2013 Mar;1831(3):514-22. doi: 10.1016/j.bbalip.2012.08.006. Epub 2012 Aug 14. Review.

PMID:
22910056
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The cellular functions of the yeast lipin homolog PAH1p are dependent on its phosphatidate phosphatase activity.

Han GS, Siniossoglou S, Carman GM.

J Biol Chem. 2007 Dec 21;282(51):37026-35. Epub 2007 Oct 30.

PMID:
17971454
[PubMed - indexed for MEDLINE]
Free Article
12.

Phosphatidate phosphatase plays role in zinc-mediated regulation of phospholipid synthesis in yeast.

Soto-Cardalda A, Fakas S, Pascual F, Choi HS, Carman GM.

J Biol Chem. 2012 Jan 6;287(2):968-77. doi: 10.1074/jbc.M111.313130. Epub 2011 Nov 28.

PMID:
22128164
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A phosphorylation-regulated amphipathic helix controls the membrane translocation and function of the yeast phosphatidate phosphatase.

Karanasios E, Han GS, Xu Z, Carman GM, Siniossoglou S.

Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17539-44. doi: 10.1073/pnas.1007974107. Epub 2010 Sep 27.

PMID:
20876142
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Yeast lipin 1 orthologue pah1p regulates vacuole homeostasis and membrane fusion.

Sasser T, Qiu QS, Karunakaran S, Padolina M, Reyes A, Flood B, Smith S, Gonzales C, Fratti RA.

J Biol Chem. 2012 Jan 13;287(3):2221-36. doi: 10.1074/jbc.M111.317420. Epub 2011 Nov 25.

PMID:
22121197
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Transcription factor Reb1p regulates DGK1-encoded diacylglycerol kinase and lipid metabolism in Saccharomyces cerevisiae.

Qiu Y, Fakas S, Han GS, Barbosa AD, Siniossoglou S, Carman GM.

J Biol Chem. 2013 Oct 4;288(40):29124-33. doi: 10.1074/jbc.M113.507392. Epub 2013 Aug 22.

PMID:
23970552
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth.

Santos-Rosa H, Leung J, Grimsey N, Peak-Chew S, Siniossoglou S.

EMBO J. 2005 Jun 1;24(11):1931-41. Epub 2005 May 5.

PMID:
15889145
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The yeast lipin orthologue Pah1p is important for biogenesis of lipid droplets.

Adeyo O, Horn PJ, Lee S, Binns DD, Chandrahas A, Chapman KD, Goodman JM.

J Cell Biol. 2011 Mar 21;192(6):1043-55. doi: 10.1083/jcb.201010111.

PMID:
21422231
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

An unconventional diacylglycerol kinase that regulates phospholipid synthesis and nuclear membrane growth.

Han GS, O'Hara L, Carman GM, Siniossoglou S.

J Biol Chem. 2008 Jul 18;283(29):20433-42. doi: 10.1074/jbc.M802903200. Epub 2008 May 5.

PMID:
18458075
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Lipins, lipids and nuclear envelope structure.

Siniossoglou S.

Traffic. 2009 Sep;10(9):1181-7. doi: 10.1111/j.1600-0854.2009.00923.x. Epub 2009 May 20. Review.

PMID:
19490535
[PubMed - indexed for MEDLINE]
20.

Phospholipid synthesis in yeast: regulation by phosphorylation.

Carman GM, Kersting MC.

Biochem Cell Biol. 2004 Feb;82(1):62-70. Review.

PMID:
15052328
[PubMed - indexed for MEDLINE]

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