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Results: 1 to 20 of 274

1.

STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation.

Verga Falzacappa MV, Vujic Spasic M, Kessler R, Stolte J, Hentze MW, Muckenthaler MU.

Blood. 2007 Jan 1;109(1):353-8. Epub 2006 Aug 31.

PMID:
16946298
[PubMed - indexed for MEDLINE]
Free Article
2.

SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression.

Mleczko-Sanecka K, Casanovas G, Ragab A, Breitkopf K, Müller A, Boutros M, Dooley S, Hentze MW, Muckenthaler MU.

Blood. 2010 Apr 1;115(13):2657-65. doi: 10.1182/blood-2009-09-238105. Epub 2009 Dec 29.

PMID:
20040761
[PubMed - indexed for MEDLINE]
Free Article
3.

Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD.

Casanovas G, Mleczko-Sanecka K, Altamura S, Hentze MW, Muckenthaler MU.

J Mol Med (Berl). 2009 May;87(5):471-80. doi: 10.1007/s00109-009-0447-2. Epub 2009 Feb 20.

PMID:
19229506
[PubMed - indexed for MEDLINE]
4.

Leptin increases the expression of the iron regulatory hormone hepcidin in HuH7 human hepatoma cells.

Chung B, Matak P, McKie AT, Sharp P.

J Nutr. 2007 Nov;137(11):2366-70.

PMID:
17951471
[PubMed - indexed for MEDLINE]
Free Article
5.

A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells.

Verga Falzacappa MV, Casanovas G, Hentze MW, Muckenthaler MU.

J Mol Med (Berl). 2008 May;86(5):531-40. doi: 10.1007/s00109-008-0313-7. Epub 2008 Apr 18.

PMID:
18421430
[PubMed - indexed for MEDLINE]
6.

Activated macrophages induce hepcidin expression in HuH7 hepatoma cells.

Matak P, Chaston TB, Chung B, Srai SK, McKie AT, Sharp PA.

Haematologica. 2009 Jun;94(6):773-80. doi: 10.3324/haematol.2008.003400. Epub 2009 May 19.

PMID:
19454498
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Hepcidin generated by hepatoma cells inhibits iron export from co-cultured THP1 monocytes.

Andriopoulos B, Pantopoulos K.

J Hepatol. 2006 Jun;44(6):1125-31. Epub 2005 Dec 5.

PMID:
16460831
[PubMed - indexed for MEDLINE]
8.

Iron responses in hepatic, intestinal and macrophage/monocyte cell lines under different culture conditions.

Jacolot S, Férec C, Mura C.

Blood Cells Mol Dis. 2008 Jul-Aug;41(1):100-8. doi: 10.1016/j.bcmd.2008.01.006. Epub 2008 Mar 5.

PMID:
18321736
[PubMed - indexed for MEDLINE]
9.

IL-6 - STAT-3 - hepcidin: linking inflammation to the iron metabolism.

Stoian I, Manolescu B, Atanasiu V, Lupescu O, Buşu C.

Rom J Intern Med. 2007;45(3):305-9. Review.

PMID:
18333366
[PubMed - indexed for MEDLINE]
10.

In vivo imaging of hepcidin promoter stimulation by iron and inflammation.

Flanagan JM, Truksa J, Peng H, Lee P, Beutler E.

Blood Cells Mol Dis. 2007 May-Jun;38(3):253-7. Epub 2007 Feb 28.

PMID:
17331760
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Role of STAT1, NF-kappaB, and C/EBPbeta in the macrophage transcriptional regulation of hepcidin by mycobacterial infection and IFN-gamma.

Sow FB, Alvarez GR, Gross RP, Satoskar AR, Schlesinger LS, Zwilling BS, Lafuse WP.

J Leukoc Biol. 2009 Nov;86(5):1247-58. doi: 10.1189/jlb.1208719. Epub 2009 Aug 3.

PMID:
19652026
[PubMed - indexed for MEDLINE]
Free Article
12.

Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPalpha.

Pinto JP, Ribeiro S, Pontes H, Thowfeequ S, Tosh D, Carvalho F, Porto G.

Blood. 2008 Jun 15;111(12):5727-33. doi: 10.1182/blood-2007-08-106195. Epub 2008 Mar 7.

PMID:
18326822
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism.

Courselaud B, Pigeon C, Inoue Y, Inoue J, Gonzalez FJ, Leroyer P, Gilot D, Boudjema K, Guguen-Guillouzo C, Brissot P, Loréal O, Ilyin G.

J Biol Chem. 2002 Oct 25;277(43):41163-70. Epub 2002 Aug 14.

PMID:
12183449
[PubMed - indexed for MEDLINE]
Free Article
14.

Pretreatment with CO-releasing molecules suppresses hepcidin expression during inflammation and endoplasmic reticulum stress through inhibition of the STAT3 and CREBH pathways.

Shin DY, Chung J, Joe Y, Pae HO, Chang KC, Cho GJ, Ryter SW, Chung HT.

Blood. 2012 Mar 15;119(11):2523-32. doi: 10.1182/blood-2011-07-366690. Epub 2012 Jan 19.

PMID:
22262759
[PubMed - indexed for MEDLINE]
Free Article
15.

Ischemia-reperfusion of rat liver modulates hepcidin in vivo expression.

Goss JA, Seu P, Gao FQ, Wyllie S.

Liver Transpl. 2005 Jul;11(7):800-6.

PMID:
15973703
[PubMed - indexed for MEDLINE]
Free Article
16.

Interleukin-6 induces hepcidin expression through STAT3.

Wrighting DM, Andrews NC.

Blood. 2006 Nov 1;108(9):3204-9. Epub 2006 Jul 11.

PMID:
16835372
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Hepcidin, a key regulator of iron metabolism, is transcriptionally activated by p53.

Weizer-Stern O, Adamsky K, Margalit O, Ashur-Fabian O, Givol D, Amariglio N, Rechavi G.

Br J Haematol. 2007 Jul;138(2):253-62.

PMID:
17593032
[PubMed - indexed for MEDLINE]
18.

Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein.

Nemeth E, Valore EV, Territo M, Schiller G, Lichtenstein A, Ganz T.

Blood. 2003 Apr 1;101(7):2461-3. Epub 2002 Nov 14.

PMID:
12433676
[PubMed - indexed for MEDLINE]
Free Article
19.

Different regulatory elements are required for response of hepcidin to interleukin-6 and bone morphogenetic proteins 4 and 9.

Truksa J, Peng H, Lee P, Beutler E.

Br J Haematol. 2007 Oct;139(1):138-47.

PMID:
17854319
[PubMed - indexed for MEDLINE]
20.

ROS mediate the hypoxic repression of the hepcidin gene by inhibiting C/EBPalpha and STAT-3.

Choi SO, Cho YS, Kim HL, Park JW.

Biochem Biophys Res Commun. 2007 Apr 27;356(1):312-7. Epub 2007 Mar 5.

PMID:
17349976
[PubMed - indexed for MEDLINE]
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