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CD4+ Th-APC with acquired peptide/MHC class I and II complexes stimulate type 1 helper CD4+ and central memory CD8+ T cell responses.

Umeshappa CS, Huang H, Xie Y, Wei Y, Mulligan SJ, Deng Y, Xiang J.

J Immunol. 2009 Jan 1;182(1):193-206.


Active CD4+ helper T cells directly stimulate CD8+ cytotoxic T lymphocyte responses in wild-type and MHC II gene knockout C57BL/6 mice and transgenic RIP-mOVA mice expressing islet beta-cell ovalbumin antigen leading to diabetes.

Ye Z, Ahmed KA, Hao S, Zhang X, Xie Y, Munegowda MA, Meng Q, Chibbar R, Xiang J.

Autoimmunity. 2008 Nov;41(7):501-11. doi: 10.1080/08916930802069256.


Antigen specificity acquisition of adoptive CD4+ regulatory T cells via acquired peptide-MHC class I complexes.

Hao S, Yuan J, Xu S, Munegowda MA, Deng Y, Gordon J, Xing Z, Xiang J.

J Immunol. 2008 Aug 15;181(4):2428-37.


Dendritic cells recruit T cell exosomes via exosomal LFA-1 leading to inhibition of CD8+ CTL responses through downregulation of peptide/MHC class I and Fas ligand-mediated cytotoxicity.

Xie Y, Zhang H, Li W, Deng Y, Munegowda MA, Chibbar R, Qureshi M, Xiang J.

J Immunol. 2010 Nov 1;185(9):5268-78. doi: 10.4049/jimmunol.1000386. Epub 2010 Sep 29.


Activation requirements of circulating antigen-specific human CD8(+) memory T cells probed with insect cell-based artificial antigen-presenting cells.

Guelly C, Küpcü Z, Zalusky D, Karner M, Zehetner M, Schweighoffer T.

Eur J Immunol. 2002 Jan;32(1):182-92.


Mature dendritic cells pulsed with exosomes stimulate efficient cytotoxic T-lymphocyte responses and antitumour immunity.

Hao S, Bai O, Li F, Yuan J, Laferte S, Xiang J.

Immunology. 2007 Jan;120(1):90-102. Epub 2006 Oct 31.


Enhanced activation of T cells by dendritic cells engineered to hyperexpress a triad of costimulatory molecules.

Hodge JW, Rad AN, Grosenbach DW, Sabzevari H, Yafal AG, Gritz L, Schlom J.

J Natl Cancer Inst. 2000 Aug 2;92(15):1228-39.


Dendritic cells activated by an anti-inflammatory agent induce CD4(+) T helper type 2 responses without impairing CD8(+) memory and effector cytotoxic T-lymphocyte responses.

Wang Y, Da'Dara AA, Thomas PG, Harn DA.

Immunology. 2010 Mar;129(3):406-17. doi: 10.1111/j.1365-2567.2009.03193.x. Epub 2009 Nov 16.

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