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Results: 1 to 20 of 157

1.

A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response.

Zhang D, Zaugg K, Mak TW, Elledge SJ.

Cell. 2006 Aug 11;126(3):529-42.

PMID:
16901786
[PubMed - indexed for MEDLINE]
Free Article
2.

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.

Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A.

J Cell Sci. 2005 Apr 15;118(Pt 8):1629-39. Epub 2005 Mar 22.

PMID:
15784679
[PubMed - indexed for MEDLINE]
Free Article
3.

Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2.

Meulmeester E, Maurice MM, Boutell C, Teunisse AF, Ovaa H, Abraham TE, Dirks RW, Jochemsen AG.

Mol Cell. 2005 May 27;18(5):565-76. Erratum in: Mol Cell. 2005 Jul 1;19(1):143-4.

PMID:
15916963
[PubMed - indexed for MEDLINE]
Free Article
4.

Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR.

Winter M, Sombroek D, Dauth I, Moehlenbrink J, Scheuermann K, Crone J, Hofmann TG.

Nat Cell Biol. 2008 Jul;10(7):812-24. doi: 10.1038/ncb1743. Epub 2008 Jun 8.

PMID:
18536714
[PubMed - indexed for MEDLINE]
5.

MDC1 is a mediator of the mammalian DNA damage checkpoint.

Stewart GS, Wang B, Bignell CR, Taylor AM, Elledge SJ.

Nature. 2003 Feb 27;421(6926):961-6.

PMID:
12607005
[PubMed - indexed for MEDLINE]
6.

MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways.

Lou Z, Minter-Dykhouse K, Wu X, Chen J.

Nature. 2003 Feb 27;421(6926):957-61.

PMID:
12607004
[PubMed - indexed for MEDLINE]
7.

E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.

Powers JT, Hong S, Mayhew CN, Rogers PM, Knudsen ES, Johnson DG.

Mol Cancer Res. 2004 Apr;2(4):203-14.

PMID:
15140942
[PubMed - indexed for MEDLINE]
Free Article
8.

NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage.

Peng A, Chen PL.

J Biol Chem. 2003 Mar 14;278(11):8873-6. Epub 2003 Jan 24.

PMID:
12551934
[PubMed - indexed for MEDLINE]
Free Article
9.

Growth of persistent foci of DNA damage checkpoint factors is essential for amplification of G1 checkpoint signaling.

Yamauchi M, Oka Y, Yamamoto M, Niimura K, Uchida M, Kodama S, Watanabe M, Sekine I, Yamashita S, Suzuki K.

DNA Repair (Amst). 2008 Mar 1;7(3):405-17. doi: 10.1016/j.dnarep.2007.11.011. Epub 2008 Jan 8.

PMID:
18248856
[PubMed - indexed for MEDLINE]
10.

53BP1, a mediator of the DNA damage checkpoint.

Wang B, Matsuoka S, Carpenter PB, Elledge SJ.

Science. 2002 Nov 15;298(5597):1435-8. Epub 2002 Oct 3.

PMID:
12364621
[PubMed - indexed for MEDLINE]
Free Article
11.

53BP1, an activator of ATM in response to DNA damage.

Mochan TA, Venere M, DiTullio RA Jr, Halazonetis TD.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):945-52.

PMID:
15279780
[PubMed - indexed for MEDLINE]
12.

Polo-like kinase 1 activated by the hepatitis B virus X protein attenuates both the DNA damage checkpoint and DNA repair resulting in partial polyploidy.

Studach L, Wang WH, Weber G, Tang J, Hullinger RL, Malbrue R, Liu X, Andrisani O.

J Biol Chem. 2010 Sep 24;285(39):30282-93. doi: 10.1074/jbc.M109.093963. Epub 2010 Jul 12.

PMID:
20624918
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions.

Gorgoulis VG, Vassiliou LV, Karakaidos P, Zacharatos P, Kotsinas A, Liloglou T, Venere M, Ditullio RA Jr, Kastrinakis NG, Levy B, Kletsas D, Yoneta A, Herlyn M, Kittas C, Halazonetis TD.

Nature. 2005 Apr 14;434(7035):907-13.

PMID:
15829965
[PubMed - indexed for MEDLINE]
14.

Protein-protein interactions occur between p53 phosphoforms and ATM and 53BP1 at sites of exogenous DNA damage.

Al Rashid ST, Harding SM, Law C, Coackley C, Bristow RG.

Radiat Res. 2011 May;175(5):588-98. doi: 10.1667/RR2084.1. Epub 2011 Mar 1.

PMID:
21361779
[PubMed - indexed for MEDLINE]
15.

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response.

Marteijn JA, Bekker-Jensen S, Mailand N, Lans H, Schwertman P, Gourdin AM, Dantuma NP, Lukas J, Vermeulen W.

J Cell Biol. 2009 Sep 21;186(6):835-47. doi: 10.1083/jcb.200902150.

PMID:
19797077
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Monoubiquitination of H2AX protein regulates DNA damage response signaling.

Pan MR, Peng G, Hung WC, Lin SY.

J Biol Chem. 2011 Aug 12;286(32):28599-607. doi: 10.1074/jbc.M111.256297. Epub 2011 Jun 15.

PMID:
21676867
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Critical role for Daxx in regulating Mdm2.

Tang J, Qu LK, Zhang J, Wang W, Michaelson JS, Degenhardt YY, El-Deiry WS, Yang X.

Nat Cell Biol. 2006 Aug;8(8):855-62. Epub 2006 Jul 16.

PMID:
16845383
[PubMed - indexed for MEDLINE]
18.

DNA damage-induced activation of p53 by the checkpoint kinase Chk2.

Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ, Mak TW.

Science. 2000 Mar 10;287(5459):1824-7.

PMID:
10710310
[PubMed - indexed for MEDLINE]
Free Article
19.

Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis.

Sluss HK, Gannon H, Coles AH, Shen Q, Eischen CM, Jones SN.

Mol Cancer Res. 2010 Feb;8(2):216-22. doi: 10.1158/1541-7786.MCR-09-0324. Epub 2010 Feb 9.

PMID:
20145032
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis.

Gostissa M, Morelli M, Mantovani F, Guida E, Piazza S, Collavin L, Brancolini C, Schneider C, Del Sal G.

J Biol Chem. 2004 Nov 12;279(46):48013-23. Epub 2004 Aug 31.

PMID:
15339933
[PubMed - indexed for MEDLINE]
Free Article

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