Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 115

1.

The DNA N-glycosylase MED1 exhibits preference for halogenated pyrimidines and is involved in the cytotoxicity of 5-iododeoxyuridine.

Turner DP, Cortellino S, Schupp JE, Caretti E, Loh T, Kinsella TJ, Bellacosa A.

Cancer Res. 2006 Aug 1;66(15):7686-93.

PMID:
16885370
[PubMed - indexed for MEDLINE]
Free Article
2.

Biphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylase.

Petronzelli F, Riccio A, Markham GD, Seeholzer SH, Stoerker J, Genuardi M, Yeung AT, Matsumoto Y, Bellacosa A.

J Biol Chem. 2000 Oct 20;275(42):32422-9.

PMID:
10930409
[PubMed - indexed for MEDLINE]
Free Article
3.

Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domain.

Petronzelli F, Riccio A, Markham GD, Seeholzer SH, Genuardi M, Karbowski M, Yeung AT, Matsumoto Y, Bellacosa A.

J Cell Physiol. 2000 Dec;185(3):473-80.

PMID:
11056019
[PubMed - indexed for MEDLINE]
4.

The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrity.

Cortellino S, Turner D, Masciullo V, Schepis F, Albino D, Daniel R, Skalka AM, Meropol NJ, Alberti C, Larue L, Bellacosa A.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15071-6. Epub 2003 Nov 12.

PMID:
14614141
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Role of MED1 (MBD4) Gene in DNA repair and human cancer.

Bellacosa A.

J Cell Physiol. 2001 May;187(2):137-44. Review.

PMID:
11267993
[PubMed - indexed for MEDLINE]
6.

Modulation of the activity of methyl binding domain protein 4 (MBD4/MED1) while processing iododeoxyuridine generated DNA mispairs.

Aziz MA, Schupp JE, Kinsella TJ.

Cancer Biol Ther. 2009 Jun;8(12):1156-63. Epub 2009 Jun 25.

PMID:
19395862
[PubMed - indexed for MEDLINE]
Free Article
7.

The main role of human thymine-DNA glycosylase is removal of thymine produced by deamination of 5-methylcytosine and not removal of ethenocytosine.

Abu M, Waters TR.

J Biol Chem. 2003 Mar 7;278(10):8739-44. Epub 2002 Dec 18.

PMID:
12493755
[PubMed - indexed for MEDLINE]
Free Article
8.

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites.

Hendrich B, Hardeland U, Ng HH, Jiricny J, Bird A.

Nature. 1999 Sep 16;401(6750):301-4. Erratum in: Nature 2000 Mar 30;404(6777):525.

PMID:
10499592
[PubMed - indexed for MEDLINE]
9.

Thymine DNA glycosylase.

Hardeland U, Bentele M, Lettieri T, Steinacher R, Jiricny J, Schär P.

Prog Nucleic Acid Res Mol Biol. 2001;68:235-53. Review.

PMID:
11554300
[PubMed - indexed for MEDLINE]
10.

Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair.

Yoon JH, Iwai S, O'Connor TR, Pfeifer GP.

Nucleic Acids Res. 2003 Sep 15;31(18):5399-404.

PMID:
12954776
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1.

Bellacosa A, Cicchillitti L, Schepis F, Riccio A, Yeung AT, Matsumoto Y, Golemis EA, Genuardi M, Neri G.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3969-74.

PMID:
10097147
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Base analog and neighboring base effects on substrate specificity of recombinant human G:T mismatch-specific thymine DNA-glycosylase.

Sibghat-Ullah, Gallinari P, Xu YZ, Goodman MF, Bloom LB, Jiricny J, Day RS 3rd.

Biochemistry. 1996 Oct 1;35(39):12926-32.

PMID:
8841138
[PubMed - indexed for MEDLINE]
13.

The role of the Escherichia coli mug protein in the removal of uracil and 3,N(4)-ethenocytosine from DNA.

Lutsenko E, Bhagwat AS.

J Biol Chem. 1999 Oct 22;274(43):31034-8.

PMID:
10521502
[PubMed - indexed for MEDLINE]
Free Article
14.

Uracil in DNA--occurrence, consequences and repair.

Krokan HE, Drabløs F, Slupphaug G.

Oncogene. 2002 Dec 16;21(58):8935-48. Review.

PMID:
12483510
[PubMed - indexed for MEDLINE]
Free Article
15.

Cutting edge: the G-U mismatch glycosylase methyl-CpG binding domain 4 is dispensable for somatic hypermutation and class switch recombination.

Bardwell PD, Martin A, Wong E, Li Z, Edelmann W, Scharff MD.

J Immunol. 2003 Feb 15;170(4):1620-4.

PMID:
12574322
[PubMed - indexed for MEDLINE]
Free Article
16.

Kinetics of the action of thymine DNA glycosylase.

Waters TR, Swann PF.

J Biol Chem. 1998 Aug 7;273(32):20007-14.

PMID:
9685338
[PubMed - indexed for MEDLINE]
Free Article
17.

5-Methylcytosine DNA glycosylase activity is also present in the human MBD4 (G/T mismatch glycosylase) and in a related avian sequence.

Zhu B, Zheng Y, Angliker H, Schwarz S, Thiry S, Siegmann M, Jost JP.

Nucleic Acids Res. 2000 Nov 1;28(21):4157-65.

PMID:
11058112
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA.

Manvilla BA, Maiti A, Begley MC, Toth EA, Drohat AC.

J Mol Biol. 2012 Jul 13;420(3):164-75. doi: 10.1016/j.jmb.2012.04.028. Epub 2012 May 2.

PMID:
22560993
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts.

Andersen S, Heine T, Sneve R, König I, Krokan HE, Epe B, Nilsen H.

Carcinogenesis. 2005 Mar;26(3):547-55. Epub 2004 Nov 25.

PMID:
15564287
[PubMed - indexed for MEDLINE]
Free Article
20.

Efficient removal of uracil from G.U mispairs by the mismatch-specific thymine DNA glycosylase from HeLa cells.

Neddermann P, Jiricny J.

Proc Natl Acad Sci U S A. 1994 Mar 1;91(5):1642-6.

PMID:
8127859
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk