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Similar articles for PubMed (Select 16868010)


In vivo function of the orphan nuclear receptor NR2E3 in establishing photoreceptor identity during mammalian retinal development.

Cheng H, Aleman TS, Cideciyan AV, Khanna R, Jacobson SG, Swaroop A.

Hum Mol Genet. 2006 Sep 1;15(17):2588-602. Epub 2006 Jul 25.


Excess cones in the retinal degeneration rd7 mouse, caused by the loss of function of orphan nuclear receptor Nr2e3, originate from early-born photoreceptor precursors.

Cheng H, Khan NW, Roger JE, Swaroop A.

Hum Mol Genet. 2011 Nov 1;20(21):4102-15. doi: 10.1093/hmg/ddr334. Epub 2011 Aug 3.


Rod differentiation factor NRL activates the expression of nuclear receptor NR2E3 to suppress the development of cone photoreceptors.

Oh EC, Cheng H, Hao H, Jia L, Khan NW, Swaroop A.

Brain Res. 2008 Oct 21;1236:16-29. doi: 10.1016/j.brainres.2008.01.028. Epub 2008 Jan 18.


Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors.

Cheng H, Khanna H, Oh EC, Hicks D, Mitton KP, Swaroop A.

Hum Mol Genet. 2004 Aug 1;13(15):1563-75. Epub 2004 Jun 9.


The photoreceptor-specific nuclear receptor Nr2e3 interacts with Crx and exerts opposing effects on the transcription of rod versus cone genes.

Peng GH, Ahmad O, Ahmad F, Liu J, Chen S.

Hum Mol Genet. 2005 Mar 15;14(6):747-64. Epub 2005 Feb 2.


The transcription factor Nr2e3 functions in retinal progenitors to suppress cone cell generation.

Haider NB, Demarco P, Nystuen AM, Huang X, Smith RS, McCall MA, Naggert JK, Nishina PM.

Vis Neurosci. 2006 Nov-Dec;23(6):917-29.


The nuclear receptor NR2E3 plays a role in human retinal photoreceptor differentiation and degeneration.

Milam AH, Rose L, Cideciyan AV, Barakat MR, Tang WX, Gupta N, Aleman TS, Wright AF, Stone EM, Sheffield VC, Jacobson SG.

Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):473-8. Epub 2002 Jan 2.


Mutations in the DNA-binding domain of NR2E3 affect in vivo dimerization and interaction with CRX.

Roduit R, Escher P, Schorderet DF.

PLoS One. 2009 Oct 12;4(10):e7379. doi: 10.1371/journal.pone.0007379.


Expression of photoreceptor-specific nuclear receptor NR2E3 in rod photoreceptors of fetal human retina.

Bumsted O'Brien KM, Cheng H, Jiang Y, Schulte D, Swaroop A, Hendrickson AE.

Invest Ophthalmol Vis Sci. 2004 Aug;45(8):2807-12.


Pias3-dependent SUMOylation directs rod photoreceptor development.

Onishi A, Peng GH, Hsu C, Alexis U, Chen S, Blackshaw S.

Neuron. 2009 Jan 29;61(2):234-46. doi: 10.1016/j.neuron.2008.12.006.


The transcription factor GTF2IRD1 regulates the topology and function of photoreceptors by modulating photoreceptor gene expression across the retina.

Masuda T, Zhang X, Berlinicke C, Wan J, Yerrabelli A, Conner EA, Kjellstrom S, Bush R, Thorgeirsson SS, Swaroop A, Chen S, Zack DJ.

J Neurosci. 2014 Nov 12;34(46):15356-68. doi: 10.1523/JNEUROSCI.2089-14.2014.


Transcriptional regulation of rod photoreceptor homeostasis revealed by in vivo NRL targetome analysis.

Hao H, Kim DS, Klocke B, Johnson KR, Cui K, Gotoh N, Zang C, Gregorski J, Gieser L, Peng W, Fann Y, Seifert M, Zhao K, Swaroop A.

PLoS Genet. 2012;8(4):e1002649. doi: 10.1371/journal.pgen.1002649. Epub 2012 Apr 12.


FIZ1 is expressed during photoreceptor maturation, and synergizes with NRL and CRX at rod-specific promoters in vitro.

Mali RS, Zhang X, Hoerauf W, Doyle D, Devitt J, Loffreda-Wren J, Mitton KP.

Exp Eye Res. 2007 Feb;84(2):349-60. Epub 2006 Dec 4.


Leukemia inhibitory factor blocks expression of Crx and Nrl transcription factors to inhibit photoreceptor differentiation.

Graham DR, Overbeek PA, Ash JD.

Invest Ophthalmol Vis Sci. 2005 Jul;46(7):2601-10.


Different effects of valproic acid on photoreceptor loss in Rd1 and Rd10 retinal degeneration mice.

Mitton KP, Guzman AE, Deshpande M, Byrd D, DeLooff C, Mkoyan K, Zlojutro P, Wallace A, Metcalf B, Laux K, Sotzen J, Tran T.

Mol Vis. 2014 Nov 4;20:1527-44. eCollection 2014.


Combinatorial regulation of photoreceptor differentiation factor, neural retina leucine zipper gene NRL, revealed by in vivo promoter analysis.

Kautzmann MA, Kim DS, Felder-Schmittbuhl MP, Swaroop A.

J Biol Chem. 2011 Aug 12;286(32):28247-55. doi: 10.1074/jbc.M111.257246. Epub 2011 Jun 14.


Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl.

Yoshida S, Mears AJ, Friedman JS, Carter T, He S, Oh E, Jing Y, Farjo R, Fleury G, Barlow C, Hero AO, Swaroop A.

Hum Mol Genet. 2004 Jul 15;13(14):1487-503. Epub 2004 May 26.


Transformation of cone precursors to functional rod photoreceptors by bZIP transcription factor NRL.

Oh EC, Khan N, Novelli E, Khanna H, Strettoi E, Swaroop A.

Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1679-84. Epub 2007 Jan 22.

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