Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 87

1.

Mirk/Dyrk1B: a multifunctional dual-specificity kinase involved in growth arrest, differentiation, and cell survival.

Mercer SE, Friedman E.

Cell Biochem Biophys. 2006;45(3):303-15. Review.

PMID:
16845176
[PubMed - indexed for MEDLINE]
2.

Mirk/dyrk1B is a Rho-induced kinase active in skeletal muscle differentiation.

Deng X, Ewton DZ, Pawlikowski B, Maimone M, Friedman E.

J Biol Chem. 2003 Oct 17;278(42):41347-54. Epub 2003 Aug 5.

PMID:
12902328
[PubMed - indexed for MEDLINE]
Free Article
3.

Mirk/Dyrk1b mediates cell survival in rhabdomyosarcomas.

Mercer SE, Ewton DZ, Shah S, Naqvi A, Friedman E.

Cancer Res. 2006 May 15;66(10):5143-50.

PMID:
16707437
[PubMed - indexed for MEDLINE]
Free Article
4.

Mirk/dyrk1B decreases the nuclear accumulation of class II histone deacetylases during skeletal muscle differentiation.

Deng X, Ewton DZ, Mercer SE, Friedman E.

J Biol Chem. 2005 Feb 11;280(6):4894-905. Epub 2004 Nov 16.

PMID:
15546868
[PubMed - indexed for MEDLINE]
Free Article
5.

Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells.

Lee K, Deng X, Friedman E.

Cancer Res. 2000 Jul 1;60(13):3631-7.

PMID:
10910078
[PubMed - indexed for MEDLINE]
Free Article
6.

The survival kinase Mirk/dyrk1B is activated through Rac1-MKK3 signaling.

Jin K, Lim S, Mercer SE, Friedman E.

J Biol Chem. 2005 Dec 23;280(51):42097-105. Epub 2005 Oct 27.

PMID:
16257974
[PubMed - indexed for MEDLINE]
Free Article
7.

The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G(0) by Mirk/dyrk1B kinase.

Deng X, Mercer SE, Shah S, Ewton DZ, Friedman E.

J Biol Chem. 2004 May 21;279(21):22498-504. Epub 2004 Mar 9.

PMID:
15010468
[PubMed - indexed for MEDLINE]
Free Article
8.

The kinase Mirk/Dyrk1B mediates cell survival in pancreatic ductal adenocarcinoma.

Deng X, Ewton DZ, Li S, Naqvi A, Mercer SE, Landas S, Friedman E.

Cancer Res. 2006 Apr 15;66(8):4149-58.

PMID:
16618736
[PubMed - indexed for MEDLINE]
Free Article
9.

Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha.

Lim S, Jin K, Friedman E.

J Biol Chem. 2002 Jul 12;277(28):25040-6. Epub 2002 Apr 29. Erratum in: J Biol Chem. 2004 Feb 6;279(6):5047.

PMID:
11980910
[PubMed - indexed for MEDLINE]
Free Article
10.

Serine/threonine kinase Mirk/Dyrk1B is an inhibitor of epithelial cell migration and is negatively regulated by the Met adaptor Ran-binding protein M.

Zou Y, Lim S, Lee K, Deng X, Friedman E.

J Biol Chem. 2003 Dec 5;278(49):49573-81. Epub 2003 Sep 18.

PMID:
14500717
[PubMed - indexed for MEDLINE]
Free Article
11.

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts.

Mercer SE, Ewton DZ, Deng X, Lim S, Mazur TR, Friedman E.

J Biol Chem. 2005 Jul 8;280(27):25788-801. Epub 2005 Apr 25.

PMID:
15851482
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mirk/Dyrk1B, a novel therapeutic target, mediates cell survival in non-small cell lung cancer cells.

Gao J, Zheng Z, Rawal B, Schell MJ, Bepler G, Haura EB.

Cancer Biol Ther. 2009 Sep;8(17):1671-9. Epub 2009 Sep 20.

PMID:
19633423
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Mirk/Dyrk1B in cancer.

Friedman E.

J Cell Biochem. 2007 Oct 1;102(2):274-9. Review.

PMID:
17583556
[PubMed - indexed for MEDLINE]
14.

The involvement of FoxO in cell survival and chemosensitivity mediated by Mirk/Dyrk1B in ovarian cancer.

Gao J, Yang X, Yin P, Hu W, Liao H, Miao Z, Pan C, Li N.

Int J Oncol. 2012 Apr;40(4):1203-9. doi: 10.3892/ijo.2011.1293. Epub 2011 Dec 12.

PMID:
22159921
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mirk/dyrk1B kinase destabilizes cyclin D1 by phosphorylation at threonine 288.

Zou Y, Ewton DZ, Deng X, Mercer SE, Friedman E.

J Biol Chem. 2004 Jun 25;279(26):27790-8. Epub 2004 Apr 9.

PMID:
15075324
[PubMed - indexed for MEDLINE]
Free Article
16.

The kinase Mirk is a potential therapeutic target in osteosarcoma.

Yang C, Ji D, Weinstein EJ, Choy E, Hornicek FJ, Wood KB, Liu X, Mankin H, Duan Z.

Carcinogenesis. 2010 Apr;31(4):552-8. doi: 10.1093/carcin/bgp330. Epub 2009 Dec 30.

PMID:
20042639
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The survival kinase Mirk/Dyrk1B is a downstream effector of oncogenic K-ras in pancreatic cancer.

Jin K, Park S, Ewton DZ, Friedman E.

Cancer Res. 2007 Aug 1;67(15):7247-55.

PMID:
17671193
[PubMed - indexed for MEDLINE]
Free Article
18.

Role for DYRK family kinases on regulation of apoptosis.

Yoshida K.

Biochem Pharmacol. 2008 Dec 1;76(11):1389-94. doi: 10.1016/j.bcp.2008.05.021. Epub 2008 Jul 2.

PMID:
18599021
[PubMed - indexed for MEDLINE]
19.

Transient arrest in a quiescent state allows ovarian cancer cells to survive suboptimal growth conditions and is mediated by both Mirk/dyrk1b and p130/RB2.

Hu J, Nakhla H, Friedman E.

Int J Cancer. 2011 Jul 15;129(2):307-18. doi: 10.1002/ijc.25692. Epub 2010 Nov 18.

PMID:
20857490
[PubMed - indexed for MEDLINE]
20.

Mirk/dyrk1B Kinase in Ovarian Cancer.

Friedman E.

Int J Mol Sci. 2013 Mar 8;14(3):5560-75. doi: 10.3390/ijms14035560.

PMID:
23528858
[PubMed]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk