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Items: 1 to 20 of 362

1.

Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer.

Vasiljeva O, Papazoglou A, Krüger A, Brodoefel H, Korovin M, Deussing J, Augustin N, Nielsen BS, Almholt K, Bogyo M, Peters C, Reinheckel T.

Cancer Res. 2006 May 15;66(10):5242-50.

2.

Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice.

Sevenich L, Werner F, Gajda M, Schurigt U, Sieber C, Müller S, Follo M, Peters C, Reinheckel T.

Oncogene. 2011 Jan 6;30(1):54-64. doi: 10.1038/onc.2010.387. Epub 2010 Sep 6.

PMID:
20818432
3.

Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice.

Vasiljeva O, Korovin M, Gajda M, Brodoefel H, Bojic L, Krüger A, Schurigt U, Sevenich L, Turk B, Peters C, Reinheckel T.

Oncogene. 2008 Jul 10;27(30):4191-9. doi: 10.1038/onc.2008.59. Epub 2008 Mar 17.

PMID:
18345026
4.

Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression.

Bengsch F, Buck A, Günther SC, Seiz JR, Tacke M, Pfeifer D, von Elverfeldt D, Sevenich L, Hillebrand LE, Kern U, Sameni M, Peters C, Sloane BF, Reinheckel T.

Oncogene. 2014 Sep 4;33(36):4474-84. doi: 10.1038/onc.2013.395. Epub 2013 Sep 30.

5.

Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion.

Williams TM, Medina F, Badano I, Hazan RB, Hutchinson J, Muller WJ, Chopra NG, Scherer PE, Pestell RG, Lisanti MP.

J Biol Chem. 2004 Dec 3;279(49):51630-46. Epub 2004 Sep 7.

6.

Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.

Sevenich L, Schurigt U, Sachse K, Gajda M, Werner F, Müller S, Vasiljeva O, Schwinde A, Klemm N, Deussing J, Peters C, Reinheckel T.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2497-502. doi: 10.1073/pnas.0907240107. Epub 2010 Jan 21.

8.

MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer.

Cuevas BD, Winter-Vann AM, Johnson NL, Johnson GL.

Oncogene. 2006 Aug 17;25(36):4998-5010. Epub 2006 Mar 27.

PMID:
16568086
9.

Disruption of the Lcn2 gene in mice suppresses primary mammary tumor formation but does not decrease lung metastasis.

Berger T, Cheung CC, Elia AJ, Mak TW.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2995-3000. doi: 10.1073/pnas.1000101107. Epub 2010 Feb 1.

10.

Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice.

Bugge TH, Lund LR, Kombrinck KK, Nielsen BS, Holmbäck K, Drew AF, Flick MJ, Witte DP, Danø K, Degen JL.

Oncogene. 1998 Jun 18;16(24):3097-104.

11.

Lung metastasis fails in MMTV-PyMT oncomice lacking S100A4 due to a T-cell deficiency in primary tumors.

Grum-Schwensen B, Klingelhöfer J, Grigorian M, Almholt K, Nielsen BS, Lukanidin E, Ambartsumian N.

Cancer Res. 2010 Feb 1;70(3):936-47. doi: 10.1158/0008-5472.CAN-09-3220. Epub 2010 Jan 26.

12.

Prognostic impact of cysteine proteases cathepsin B and cathepsin L in pancreatic adenocarcinoma.

Niedergethmann M, Wostbrock B, Sturm JW, Willeke F, Post S, Hildenbrand R.

Pancreas. 2004 Oct;29(3):204-11.

PMID:
15367886
13.

MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease.

Szabova L, Chrysovergis K, Yamada SS, Holmbeck K.

Oncogene. 2008 May 22;27(23):3274-81. Epub 2007 Dec 10.

PMID:
18071307
14.

Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice: correlation to human disease.

Qiu TH, Chandramouli GV, Hunter KW, Alkharouf NW, Green JE, Liu ET.

Cancer Res. 2004 Sep 1;64(17):5973-81.

15.

Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers.

Weng D, Penzner JH, Song B, Koido S, Calderwood SK, Gong J.

Breast Cancer Res. 2012 Jan 25;14(1):R18.

16.

Dual stromelysin-3 function during natural mouse mammary tumor virus-ras tumor progression.

Andarawewa KL, Boulay A, Masson R, Mathelin C, Stoll I, Tomasetto C, Chenard MP, Gintz M, Bellocq JP, Rio MC.

Cancer Res. 2003 Sep 15;63(18):5844-9.

17.

N-cadherin signaling potentiates mammary tumor metastasis via enhanced extracellular signal-regulated kinase activation.

Hulit J, Suyama K, Chung S, Keren R, Agiostratidou G, Shan W, Dong X, Williams TM, Lisanti MP, Knudsen K, Hazan RB.

Cancer Res. 2007 Apr 1;67(7):3106-16.

18.

Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomas.

Pickup MW, Laklai H, Acerbi I, Owens P, Gorska AE, Chytil A, Aakre M, Weaver VM, Moses HL.

Cancer Res. 2013 Sep 1;73(17):5336-46. doi: 10.1158/0008-5472.CAN-13-0012. Epub 2013 Jul 15.

19.
20.

Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model.

Merchan JR, Tang J, Hu G, Lin Y, Mutter W, Tong C, Karumanchi SA, Russell SJ, Sukhatme VP.

J Natl Cancer Inst. 2006 Jun 7;98(11):756-64.

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