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Results: 1 to 20 of 123

1.

DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A.

Bergink S, Salomons FA, Hoogstraten D, Groothuis TA, de Waard H, Wu J, Yuan L, Citterio E, Houtsmuller AB, Neefjes J, Hoeijmakers JH, Vermeulen W, Dantuma NP.

Genes Dev. 2006 May 15;20(10):1343-52.

PMID:
16702407
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response.

Marteijn JA, Bekker-Jensen S, Mailand N, Lans H, Schwertman P, Gourdin AM, Dantuma NP, Lukas J, Vermeulen W.

J Cell Biol. 2009 Sep 21;186(6):835-47. doi: 10.1083/jcb.200902150.

PMID:
19797077
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.

Mu JJ, Wang Y, Luo H, Leng M, Zhang J, Yang T, Besusso D, Jung SY, Qin J.

J Biol Chem. 2007 Jun 15;282(24):17330-4. Epub 2007 May 3.

PMID:
17478428
[PubMed - indexed for MEDLINE]
Free Article
4.

RNF8-dependent and RNF8-independent regulation of 53BP1 in response to DNA damage.

Sakasai R, Tibbetts R.

J Biol Chem. 2008 May 16;283(20):13549-55. doi: 10.1074/jbc.M710197200. Epub 2008 Mar 12.

PMID:
18337245
[PubMed - indexed for MEDLINE]
Free Article
5.

H2AX phosphorylation after UV irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinase.

Hanasoge S, Ljungman M.

Carcinogenesis. 2007 Nov;28(11):2298-304. Epub 2007 Jul 5.

PMID:
17615256
[PubMed - indexed for MEDLINE]
Free Article
6.

Perturbed gap-filling synthesis in nucleotide excision repair causes histone H2AX phosphorylation in human quiescent cells.

Matsumoto M, Yaginuma K, Igarashi A, Imura M, Hasegawa M, Iwabuchi K, Date T, Mori T, Ishizaki K, Yamashita K, Inobe M, Matsunaga T.

J Cell Sci. 2007 Mar 15;120(Pt 6):1104-12. Epub 2007 Feb 27.

PMID:
17327276
[PubMed - indexed for MEDLINE]
Free Article
7.

The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A.

Guerrero-Santoro J, Kapetanaki MG, Hsieh CL, Gorbachinsky I, Levine AS, Rapić-Otrin V.

Cancer Res. 2008 Jul 1;68(13):5014-22. doi: 10.1158/0008-5472.CAN-07-6162.

PMID:
18593899
[PubMed - indexed for MEDLINE]
Free Article
8.
9.

BRCT domain interactions with phospho-histone H2A target Crb2 to chromatin at double-strand breaks and maintain the DNA damage checkpoint.

Sofueva S, Du LL, Limbo O, Williams JS, Russell P.

Mol Cell Biol. 2010 Oct;30(19):4732-43. doi: 10.1128/MCB.00413-10. Epub 2010 Aug 2.

PMID:
20679485
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.

Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, Wang SY, Eppink B, Chung YM, Shalev G, Shema E, Shkedy D, Smorodinsky NI, van Vliet N, Kuster B, Mann M, Ciechanover A, Dahm-Daphi J, Kanaar R, Hu MC, Chen DJ, Oren M, Shiloh Y.

Mol Cell. 2011 Mar 4;41(5):529-42. doi: 10.1016/j.molcel.2011.02.015.

PMID:
21362549
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Role of ubiquitin protein ligase Ring2 in DNA damage of human bronchial epithelial cells exposed to benzo[a]pyrene.

Yang J, Wang Z, Chen W, Yin J.

J Biochem Mol Toxicol. 2013 Jul;27(7):357-63. doi: 10.1002/jbt.21497. Epub 2013 May 24.

PMID:
23712474
[PubMed - indexed for MEDLINE]
12.

Human SNF5/INI1, a component of the human SWI/SNF chromatin remodeling complex, promotes nucleotide excision repair by influencing ATM recruitment and downstream H2AX phosphorylation.

Ray A, Mir SN, Wani G, Zhao Q, Battu A, Zhu Q, Wang QE, Wani AA.

Mol Cell Biol. 2009 Dec;29(23):6206-19. doi: 10.1128/MCB.00503-09. Epub 2009 Oct 5.

PMID:
19805520
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The nucleotide excision repair pathway is required for UV-C-induced apoptosis in Caenorhabditis elegans.

Stergiou L, Doukoumetzidis K, Sendoel A, Hengartner MO.

Cell Death Differ. 2007 Jun;14(6):1129-38. Epub 2007 Mar 9.

PMID:
17347667
[PubMed - indexed for MEDLINE]
Free Article
14.

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress.

Ward IM, Chen J.

J Biol Chem. 2001 Dec 21;276(51):47759-62. Epub 2001 Oct 22.

PMID:
11673449
[PubMed - indexed for MEDLINE]
Free Article
15.

Polycomb group proteins in the DNA damage response: a link between radiation resistance and "stemness".

Gieni RS, Ismail IH, Campbell S, Hendzel MJ.

Cell Cycle. 2011 Mar 15;10(6):883-94. Epub 2011 Mar 15.

PMID:
21346409
[PubMed - indexed for MEDLINE]
Free Article
16.

Crosstalk between histone modifications during the DNA damage response.

van Attikum H, Gasser SM.

Trends Cell Biol. 2009 May;19(5):207-17. doi: 10.1016/j.tcb.2009.03.001. Epub 2009 Apr 1. Review.

PMID:
19342239
[PubMed - indexed for MEDLINE]
17.

ATR-dependent checkpoint modulates XPA nuclear import in response to UV irradiation.

Wu X, Shell SM, Liu Y, Zou Y.

Oncogene. 2007 Feb 1;26(5):757-64. Epub 2006 Jul 24.

PMID:
16862173
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage.

Wang H, Zhai L, Xu J, Joo HY, Jackson S, Erdjument-Bromage H, Tempst P, Xiong Y, Zhang Y.

Mol Cell. 2006 May 5;22(3):383-94.

PMID:
16678110
[PubMed - indexed for MEDLINE]
Free Article
19.

DNA damage binding protein component DDB1 participates in nucleotide excision repair through DDB2 DNA-binding and cullin 4A ubiquitin ligase activity.

Li J, Wang QE, Zhu Q, El-Mahdy MA, Wani G, Praetorius-Ibba M, Wani AA.

Cancer Res. 2006 Sep 1;66(17):8590-7.

PMID:
16951172
[PubMed - indexed for MEDLINE]
Free Article
20.

Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation.

Toh GW, O'Shaughnessy AM, Jimeno S, Dobbie IM, Grenon M, Maffini S, O'Rorke A, Lowndes NF.

DNA Repair (Amst). 2006 Jun 10;5(6):693-703. Epub 2006 May 2.

PMID:
16650810
[PubMed - indexed for MEDLINE]

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