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Results: 1 to 20 of 185

1.

Identification of rotenone-induced modifications in alpha-synuclein using affinity pull-down and tandem mass spectrometry.

Mirzaei H, Schieler JL, Rochet JC, Regnier F.

Anal Chem. 2006 Apr 1;78(7):2422-31.

PMID:
16579629
[PubMed - indexed for MEDLINE]
2.

An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage.

Sherer TB, Betarbet R, Stout AK, Lund S, Baptista M, Panov AV, Cookson MR, Greenamyre JT.

J Neurosci. 2002 Aug 15;22(16):7006-15.

PMID:
12177198
[PubMed - indexed for MEDLINE]
Free Article
3.

Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system.

Betarbet R, Canet-Aviles RM, Sherer TB, Mastroberardino PG, McLendon C, Kim JH, Lund S, Na HM, Taylor G, Bence NF, Kopito R, Seo BB, Yagi T, Yagi A, Klinefelter G, Cookson MR, Greenamyre JT.

Neurobiol Dis. 2006 May;22(2):404-20. Epub 2006 Jan 24.

PMID:
16439141
[PubMed - indexed for MEDLINE]
4.

Rotenone induces oxidative stress and dopaminergic neuron damage in organotypic substantia nigra cultures.

Testa CM, Sherer TB, Greenamyre JT.

Brain Res Mol Brain Res. 2005 Mar 24;134(1):109-18. Epub 2005 Jan 6.

PMID:
15790535
[PubMed - indexed for MEDLINE]
5.

Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity.

Smith WW, Jiang H, Pei Z, Tanaka Y, Morita H, Sawa A, Dawson VL, Dawson TM, Ross CA.

Hum Mol Genet. 2005 Dec 15;14(24):3801-11. Epub 2005 Oct 20.

PMID:
16239241
[PubMed - indexed for MEDLINE]
Free Article
6.

Role of oxidative damage in protein aggregation associated with Parkinson's disease and related disorders.

Norris EH, Giasson BI.

Antioxid Redox Signal. 2005 May-Jun;7(5-6):672-84. Review.

PMID:
15890012
[PubMed - indexed for MEDLINE]
7.

Prolyl-isomerase Pin1 accumulates in lewy bodies of parkinson disease and facilitates formation of alpha-synuclein inclusions.

Ryo A, Togo T, Nakai T, Hirai A, Nishi M, Yamaguchi A, Suzuki K, Hirayasu Y, Kobayashi H, Perrem K, Liou YC, Aoki I.

J Biol Chem. 2006 Feb 17;281(7):4117-25. Epub 2005 Dec 19.

PMID:
16365047
[PubMed - indexed for MEDLINE]
Free Article
8.

Effect of 4-hydroxy-2-nonenal modification on alpha-synuclein aggregation.

Qin Z, Hu D, Han S, Reaney SH, Di Monte DA, Fink AL.

J Biol Chem. 2007 Feb 23;282(8):5862-70. Epub 2006 Dec 21.

PMID:
17189262
[PubMed - indexed for MEDLINE]
Free Article
9.

Analysis of alpha-synuclein-associated proteins by quantitative proteomics.

Zhou Y, Gu G, Goodlett DR, Zhang T, Pan C, Montine TJ, Montine KS, Aebersold RH, Zhang J.

J Biol Chem. 2004 Sep 10;279(37):39155-64. Epub 2004 Jul 1.

PMID:
15234983
[PubMed - indexed for MEDLINE]
Free Article
10.

Rotenone induces aggregation of gamma-tubulin protein and subsequent disorganization of the centrosome: relevance to formation of inclusion bodies and neurodegeneration.

Diaz-Corrales FJ, Asanuma M, Miyazaki I, Miyoshi K, Ogawa N.

Neuroscience. 2005;133(1):117-35.

PMID:
15893636
[PubMed - indexed for MEDLINE]
11.

Alpha-synuclein and Parkinson's disease: selective neurodegenerative effect of alpha-synuclein fragment on dopaminergic neurons in vitro and in vivo.

Forloni G, Bertani I, Calella AM, Thaler F, Invernizzi R.

Ann Neurol. 2000 May;47(5):632-40.

PMID:
10805334
[PubMed - indexed for MEDLINE]
12.
13.

Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain.

Devi L, Raghavendran V, Prabhu BM, Avadhani NG, Anandatheerthavarada HK.

J Biol Chem. 2008 Apr 4;283(14):9089-100. doi: 10.1074/jbc.M710012200. Epub 2008 Feb 1.

PMID:
18245082
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies.

Kramer ML, Schulz-Schaeffer WJ.

J Neurosci. 2007 Feb 7;27(6):1405-10.

PMID:
17287515
[PubMed - indexed for MEDLINE]
Free Article
15.

Formation of dopamine-mediated alpha-synuclein-soluble oligomers requires methionine oxidation.

Leong SL, Pham CL, Galatis D, Fodero-Tavoletti MT, Perez K, Hill AF, Masters CL, Ali FE, Barnham KJ, Cappai R.

Free Radic Biol Med. 2009 May 15;46(10):1328-37. doi: 10.1016/j.freeradbiomed.2009.02.009. Epub 2009 Feb 25.

PMID:
19248830
[PubMed - indexed for MEDLINE]
16.

Mechanisms of Suppression of {alpha}-Synuclein Neurotoxicity by Geldanamycin in Drosophila.

Auluck PK, Meulener MC, Bonini NM.

J Biol Chem. 2005 Jan 28;280(4):2873-8. Epub 2004 Nov 18.

PMID:
15556931
[PubMed - indexed for MEDLINE]
Free Article
17.

Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease.

Reynolds AD, Glanzer JG, Kadiu I, Ricardo-Dukelow M, Chaudhuri A, Ciborowski P, Cerny R, Gelman B, Thomas MP, Mosley RL, Gendelman HE.

J Neurochem. 2008 Mar;104(6):1504-25. Epub 2007 Nov 22.

PMID:
18036154
[PubMed - indexed for MEDLINE]
18.

[Clinical and pathological study on early diagnosis of Parkinson's disease and dementia with Lewy bodies].

Orimo S.

Rinsho Shinkeigaku. 2008 Jan;48(1):11-24. Review. Japanese.

PMID:
18386627
[PubMed - indexed for MEDLINE]
19.

Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.

Periquet M, Fulga T, Myllykangas L, Schlossmacher MG, Feany MB.

J Neurosci. 2007 Mar 21;27(12):3338-46.

PMID:
17376994
[PubMed - indexed for MEDLINE]
Free Article
20.

The role of ubiquitin linkages on alpha-synuclein induced-toxicity in a Drosophila model of Parkinson's disease.

Lee FK, Wong AK, Lee YW, Wan OW, Chan HY, Chung KK.

J Neurochem. 2009 Jul;110(1):208-19. doi: 10.1111/j.1471-4159.2009.06124.x. Epub 2009 Apr 27.

PMID:
19457126
[PubMed - indexed for MEDLINE]
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