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Items: 1 to 20 of 1450

1.

Analysis of gene expression differences between utrophin/dystrophin-deficient vs mdx skeletal muscles reveals a specific upregulation of slow muscle genes in limb muscles.

Baker PE, Kearney JA, Gong B, Merriam AP, Kuhn DE, Porter JD, Rafael-Fortney JA.

Neurogenetics. 2006 May;7(2):81-91. Epub 2006 Mar 9.

PMID:
16525850
2.

The sparing of extraocular muscle in dystrophinopathy is lost in mice lacking utrophin and dystrophin.

Porter JD, Rafael JA, Ragusa RJ, Brueckner JK, Trickett JI, Davies KE.

J Cell Sci. 1998 Jul;111 ( Pt 13):1801-11.

3.

Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice.

Rafael JA, Tinsley JM, Potter AC, Deconinck AE, Davies KE.

Nat Genet. 1998 May;19(1):79-82.

PMID:
9590295
4.

Utrophin deficiency worsens cardiac contractile dysfunction present in dystrophin-deficient mdx mice.

Janssen PM, Hiranandani N, Mays TA, Rafael-Fortney JA.

Am J Physiol Heart Circ Physiol. 2005 Dec;289(6):H2373-8. Epub 2005 Jul 15.

5.

Consequences of the combined deficiency in dystrophin and utrophin on the mechanical properties and myosin composition of some limb and respiratory muscles of the mouse.

Deconinck N, Rafael JA, Beckers-Bleukx G, Kahn D, Deconinck AE, Davies KE, Gillis JM.

Neuromuscul Disord. 1998 Aug;8(6):362-70.

PMID:
9713852
6.

Muscle regeneration in dystrophin-deficient mdx mice studied by gene expression profiling.

Turk R, Sterrenburg E, de Meijer EJ, van Ommen GJ, den Dunnen JT, 't Hoen PA.

BMC Genomics. 2005 Jul 13;6:98.

8.

Restoration of all dystrophin protein interactions by functional domains in trans does not rescue dystrophy.

Gardner KL, Kearney JA, Edwards JD, Rafael-Fortney JA.

Gene Ther. 2006 May;13(9):744-51.

PMID:
16307000
9.

Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.

Wakefield PM, Tinsley JM, Wood MJ, Gilbert R, Karpati G, Davies KE.

Gene Ther. 2000 Feb;7(3):201-4.

10.

Pharmacological activation of PPARbeta/delta stimulates utrophin A expression in skeletal muscle fibers and restores sarcolemmal integrity in mature mdx mice.

Miura P, Chakkalakal JV, Boudreault L, Bélanger G, Hébert RL, Renaud JM, Jasmin BJ.

Hum Mol Genet. 2009 Dec 1;18(23):4640-9. doi: 10.1093/hmg/ddp431. Epub 2009 Sep 10.

11.

Alterations in Notch signalling in skeletal muscles from mdx and dko dystrophic mice and patients with Duchenne muscular dystrophy.

Church JE, Trieu J, Chee A, Naim T, Gehrig SM, Lamon S, Angelini C, Russell AP, Lynch GS.

Exp Physiol. 2014 Apr;99(4):675-87. doi: 10.1113/expphysiol.2013.077255. Epub 2014 Jan 17.

PMID:
24443351
12.

Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins.

Moghadaszadeh B, Albrechtsen R, Guo LT, Zaik M, Kawaguchi N, Borup RH, Kronqvist P, Schroder HD, Davies KE, Voit T, Nielsen FC, Engvall E, Wewer UM.

Hum Mol Genet. 2003 Oct 1;12(19):2467-79. Epub 2003 Aug 5.

13.

Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy.

Deconinck AE, Rafael JA, Skinner JA, Brown SC, Potter AC, Metzinger L, Watt DJ, Dickson JG, Tinsley JM, Davies KE.

Cell. 1997 Aug 22;90(4):717-27.

14.

Interleukin 6 induces overexpression of the sarcolemmal utrophin in neonatal mdx skeletal muscle.

Fujimori K, Itoh Y, Yamamoto K, Miyagoe-Suzuki Y, Yuasa K, Yoshizaki K, Yamamoto H, Takeda S.

Hum Gene Ther. 2002 Mar 1;13(4):509-18.

PMID:
11874629
15.

Expression profiling in stably regenerating skeletal muscle of dystrophin-deficient mdx mice.

Boer JM, de Meijer EJ, Mank EM, van Ommen GB, den Dunnen JT.

Neuromuscul Disord. 2002 Oct;12 Suppl 1:S118-24.

PMID:
12206806
16.

Differential effects of dystrophin and utrophin gene transfer in immunocompetent muscular dystrophy (mdx) mice.

Ebihara S, Guibinga GH, Gilbert R, Nalbantoglu J, Massie B, Karpati G, Petrof BJ.

Physiol Genomics. 2000 Sep 8;3(3):133-44.

PMID:
11015608
17.

Dissection of temporal gene expression signatures of affected and spared muscle groups in dystrophin-deficient (mdx) mice.

Porter JD, Merriam AP, Leahy P, Gong B, Khanna S.

Hum Mol Genet. 2003 Aug 1;12(15):1813-21.

18.

Immune response to adenovirus-delivered antigens upregulates utrophin and results in mitigation of muscle pathology in mdx mice.

Yamamoto K, Yuasa K, Miyagoe Y, Hosaka Y, Tsukita K, Yamamoto H, Nabeshima YI, Takeda S.

Hum Gene Ther. 2000 Mar 20;11(5):669-80.

PMID:
10757347
19.

Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene.

Tinsley JM, Potter AC, Phelps SR, Fisher R, Trickett JI, Davies KE.

Nature. 1996 Nov 28;384(6607):349-53.

PMID:
8934518
20.

Downstream utrophin enhancer is required for expression of utrophin in skeletal muscle.

Tanihata J, Suzuki N, Miyagoe-Suzuki Y, Imaizumi K, Takeda S.

J Gene Med. 2008 Jun;10(6):702-13. doi: 10.1002/jgm.1190.

PMID:
18338831
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