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Items: 1 to 20 of 156

1.

Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation.

Swiatek W, Kang H, Garcia BA, Shabanowitz J, Coombs GS, Hunt DF, Virshup DM.

J Biol Chem. 2006 May 5;281(18):12233-41. Epub 2006 Mar 2.

2.

CKIepsilon/discs overgrown promotes both Wnt-Fz/beta-catenin and Fz/PCP signaling in Drosophila.

Klein TJ, Jenny A, Djiane A, Mlodzik M.

Curr Biol. 2006 Jul 11;16(13):1337-43.

3.

LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin.

Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E.

Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):8032-7. doi: 10.1073/pnas.0803025105. Epub 2008 May 28.

4.

Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6.

Wu G, Huang H, Garcia Abreu J, He X.

PLoS One. 2009;4(3):e4926. doi: 10.1371/journal.pone.0004926. Epub 2009 Mar 18.

5.

Role of the intracellular domains of LRP5 and LRP6 in activating the Wnt canonical pathway.

Mi K, Johnson GV.

J Cell Biochem. 2005 May 15;95(2):328-38.

PMID:
15778991
6.

G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.

Chen M, Philipp M, Wang J, Premont RT, Garrison TR, Caron MG, Lefkowitz RJ, Chen W.

J Biol Chem. 2009 Dec 11;284(50):35040-8. doi: 10.1074/jbc.M109.047456. Epub 2009 Oct 2.

7.

Regulation of Lrp6 phosphorylation.

Niehrs C, Shen J.

Cell Mol Life Sci. 2010 Aug;67(15):2551-62. doi: 10.1007/s00018-010-0329-3. Epub 2010 Mar 14. Review.

PMID:
20229235
8.

New steps in the Wnt/beta-catenin signal transduction pathway.

Sakanaka C, Sun TQ, Williams LT.

Recent Prog Horm Res. 2000;55:225-36. Review.

PMID:
11036939
9.

Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6.

Bourhis E, Tam C, Franke Y, Bazan JF, Ernst J, Hwang J, Costa M, Cochran AG, Hannoush RN.

J Biol Chem. 2010 Mar 19;285(12):9172-9. doi: 10.1074/jbc.M109.092130. Epub 2010 Jan 21.

10.
11.

Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression.

Nam JS, Turcotte TJ, Smith PF, Choi S, Yoon JK.

J Biol Chem. 2006 May 12;281(19):13247-57. Epub 2006 Mar 16.

12.

Identification of zinc-finger BED domain-containing 3 (Zbed3) as a novel Axin-interacting protein that activates Wnt/beta-catenin signaling.

Chen T, Li M, Ding Y, Zhang LS, Xi Y, Pan WJ, Tao DL, Wang JY, Li L.

J Biol Chem. 2009 Mar 13;284(11):6683-9. doi: 10.1074/jbc.M807753200. Epub 2009 Jan 13.

13.

LRP6 mediates Wnt/β-catenin signaling and regulates adipogenic differentiation in human mesenchymal stem cells.

Peröbner I, Karow M, Jochum M, Neth P.

Int J Biochem Cell Biol. 2012 Nov;44(11):1970-82. doi: 10.1016/j.biocel.2012.07.025. Epub 2012 Aug 2.

PMID:
22871567
14.

Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation.

Ding Y, Xi Y, Chen T, Wang JY, Tao DL, Wu ZL, Li YP, Li C, Zeng R, Li L.

J Cell Biol. 2008 Sep 8;182(5):865-72. doi: 10.1083/jcb.200803147. Epub 2008 Sep 1.

15.

Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6.

MacDonald BT, Yokota C, Tamai K, Zeng X, He X.

J Biol Chem. 2008 Jun 6;283(23):16115-23. doi: 10.1074/jbc.M800327200. Epub 2008 Mar 24.

16.

Regulation of casein kinase I epsilon activity by Wnt signaling.

Swiatek W, Tsai IC, Klimowski L, Pepler A, Barnette J, Yost HJ, Virshup DM.

J Biol Chem. 2004 Mar 26;279(13):13011-7. Epub 2004 Jan 13.

17.

Casein kinase Iepsilon modulates the signaling specificities of dishevelled.

Cong F, Schweizer L, Varmus H.

Mol Cell Biol. 2004 Mar;24(5):2000-11.

18.

The low-density lipoprotein receptor-related protein 10 is a negative regulator of the canonical Wnt/beta-catenin signaling pathway.

Jeong YH, Sekiya M, Hirata M, Ye M, Yamagishi A, Lee SM, Kang MJ, Hosoda A, Fukumura T, Kim DH, Saeki S.

Biochem Biophys Res Commun. 2010 Feb 19;392(4):495-9. doi: 10.1016/j.bbrc.2010.01.049. Epub 2010 Jan 20.

PMID:
20093106
19.

A p120-catenin-CK1epsilon complex regulates Wnt signaling.

Casagolda D, Del Valle-Pérez B, Valls G, Lugilde E, Vinyoles M, Casado-Vela J, Solanas G, Batlle E, Reynolds AB, Casal JI, de Herreros AG, Duñach M.

J Cell Sci. 2010 Aug 1;123(Pt 15):2621-31. doi: 10.1242/jcs.067512.

20.

Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling.

Yamamoto H, Sakane H, Yamamoto H, Michiue T, Kikuchi A.

Dev Cell. 2008 Jul;15(1):37-48. doi: 10.1016/j.devcel.2008.04.015.

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