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Results: 1 to 20 of 154

1.

IMP dehydrogenase inhibitor mycophenolate mofetil induces caspase-dependent apoptosis and cell cycle inhibition in multiple myeloma cells.

Takebe N, Cheng X, Fandy TE, Srivastava RK, Wu S, Shankar S, Bauer K, Shaughnessy J, Tricot G.

Mol Cancer Ther. 2006 Feb;5(2):457-66.

PMID:
16505121
[PubMed - indexed for MEDLINE]
Free Article
2.

Phase I clinical trial of the inosine monophosphate dehydrogenase inhibitor mycophenolate mofetil (cellcept) in advanced multiple myeloma patients.

Takebe N, Cheng X, Wu S, Bauer K, Goloubeva OG, Fenton RG, Heyman M, Rapoport AP, Badros A, Shaughnessy J, Ross D, Meisenberg B, Tricot G.

Clin Cancer Res. 2004 Dec 15;10(24):8301-8.

PMID:
15623606
[PubMed - indexed for MEDLINE]
Free Article
3.

Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway.

Ishitsuka K, Hideshima T, Hamasaki M, Raje N, Kumar S, Podar K, Le Gouill S, Shiraishi N, Yasui H, Roccaro AM, Tai YZ, Chauhan D, Fram R, Tamura K, Jain J, Anderson KC.

Oncogene. 2005 Sep 1;24(38):5888-96.

PMID:
15940263
[PubMed - indexed for MEDLINE]
4.

Farnesyltransferase inhibitor BMS-214662 induces apoptosis in myeloma cells through PUMA up-regulation, Bax and Bak activation, and Mcl-1 elimination.

Gómez-Benito M, Marzo I, Anel A, Naval J.

Mol Pharmacol. 2005 Jun;67(6):1991-8. Epub 2005 Feb 28.

PMID:
15738311
[PubMed - indexed for MEDLINE]
Free Article
5.

Induction of apoptosis in IL-3-dependent hematopoietic cell lines by guanine nucleotide depletion.

Gu JJ, Gathy K, Santiago L, Chen E, Huang M, Graves LM, Mitchell BS.

Blood. 2003 Jun 15;101(12):4958-65. Epub 2003 Feb 27.

PMID:
12609835
[PubMed - indexed for MEDLINE]
Free Article
6.
7.

4-Hydroxytamoxifen inhibits proliferation of multiple myeloma cells in vitro through down-regulation of c-Myc, up-regulation of p27Kip1, and modulation of Bcl-2 family members.

Gauduchon J, Gouilleux F, Maillard S, Marsaud V, Renoir JM, Sola B.

Clin Cancer Res. 2005 Mar 15;11(6):2345-54.

PMID:
15788686
[PubMed - indexed for MEDLINE]
Free Article
9.

Petrotetrayndiol A induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells through cytochrome c-mediated activation of caspases.

Choi HJ, Yee SB, Park SE, Im E, Jung JH, Chung HY, Choi YH, Kim ND.

Cancer Lett. 2006 Feb 8;232(2):214-25. Epub 2005 Apr 26.

PMID:
16458118
[PubMed - indexed for MEDLINE]
10.

Arsenic trioxide-mediated growth inhibition in MC/CAR myeloma cells via cell cycle arrest in association with induction of cyclin-dependent kinase inhibitor, p21, and apoptosis.

Park WH, Seol JG, Kim ES, Hyun JM, Jung CW, Lee CC, Kim BK, Lee YY.

Cancer Res. 2000 Jun 1;60(11):3065-71.

PMID:
10850458
[PubMed - indexed for MEDLINE]
Free Article
11.

Dihydroorotate dehydrogenase inhibitor A771726 (leflunomide) induces apoptosis and diminishes proliferation of multiple myeloma cells.

Baumann P, Mandl-Weber S, Völkl A, Adam C, Bumeder I, Oduncu F, Schmidmaier R.

Mol Cancer Ther. 2009 Feb;8(2):366-75. doi: 10.1158/1535-7163.MCT-08-0664. Epub 2009 Jan 27.

PMID:
19174558
[PubMed - indexed for MEDLINE]
Free Article
12.

Monensin-mediated growth inhibition in NCI-H929 myeloma cells via cell cycle arrest and apoptosis.

Park WH, Kim ES, Kim BK, Lee YY.

Int J Oncol. 2003 Jul;23(1):197-204.

PMID:
12792794
[PubMed - indexed for MEDLINE]
13.

Matrine induces apoptosis of human multiple myeloma cells via activation of the mitochondrial pathway.

Han Y, Zhang S, Wu J, Yu K, Zhang Y, Yin L, Bi L.

Leuk Lymphoma. 2010 Jul;51(7):1337-46. doi: 10.3109/10428194.2010.488708.

PMID:
20528251
[PubMed - indexed for MEDLINE]
14.

GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death.

Streetly MJ, Maharaj L, Joel S, Schey SA, Gribben JG, Cotter FE.

Blood. 2010 May 13;115(19):3939-48. doi: 10.1182/blood-2009-10-251660. Epub 2010 Feb 26.

PMID:
20190189
[PubMed - indexed for MEDLINE]
Free Article
15.

Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction.

Seo SK, Lee HC, Woo SH, Jin HO, Yoo DH, Lee SJ, An S, Choe TB, Park MJ, Hong SI, Park IC, Rhee CH.

Apoptosis. 2007 Jan;12(1):195-209.

PMID:
17136320
[PubMed - indexed for MEDLINE]
16.

Effector mechanisms of norcantharidin-induced mitotic arrest and apoptosis in human hepatoma cells.

Chen YN, Chen JC, Yin SC, Wang GS, Tsauer W, Hsu SF, Hsu SL.

Int J Cancer. 2002 Jul 10;100(2):158-65.

PMID:
12115564
[PubMed - indexed for MEDLINE]
17.

Transforming growth factor-beta1 inhibits all-trans retinoic acid-induced apoptosis.

Soucek K, Pacherník J, Kubala L, Vondrácek J, Hofmanová J, Kozubík A.

Leuk Res. 2006 May;30(5):607-23. Epub 2005 Oct 19.

PMID:
16242776
[PubMed - indexed for MEDLINE]
18.

Molecular mechanisms of nutlin-induced apoptosis in multiple myeloma: evidence for p53-transcription-dependent and -independent pathways.

Saha MN, Jiang H, Chang H.

Cancer Biol Ther. 2010 Sep 15;10(6):567-78. Epub 2010 Oct 1.

PMID:
20595817
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Green tea component, catechin, induces apoptosis of human malignant B cells via production of reactive oxygen species.

Nakazato T, Ito K, Ikeda Y, Kizaki M.

Clin Cancer Res. 2005 Aug 15;11(16):6040-9.

PMID:
16115949
[PubMed - indexed for MEDLINE]
Free Article
20.

The gold compound auranofin induces apoptosis of human multiple myeloma cells through both down-regulation of STAT3 and inhibition of NF-κB activity.

Nakaya A, Sagawa M, Muto A, Uchida H, Ikeda Y, Kizaki M.

Leuk Res. 2011 Feb;35(2):243-9. doi: 10.1016/j.leukres.2010.05.011. Epub 2010 Jun 12.

PMID:
20542334
[PubMed - indexed for MEDLINE]

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