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Results: 1 to 20 of 103

1.

Amyloid-beta peptide binds with heme to form a peroxidase: relationship to the cytopathologies of Alzheimer's disease.

Atamna H, Boyle K.

Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3381-6. Epub 2006 Feb 21.

PMID:
16492752
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Heme binding to Amyloid-beta peptide: mechanistic role in Alzheimer's disease.

Atamna H.

J Alzheimers Dis. 2006 Nov;10(2-3):255-66. Review.

PMID:
17119291
[PubMed - indexed for MEDLINE]
3.

Amino acids variations in amyloid-beta peptides, mitochondrial dysfunction, and new therapies for Alzheimer's disease.

Atamna H.

J Bioenerg Biomembr. 2009 Oct;41(5):457-64. doi: 10.1007/s10863-009-9246-2. Review.

PMID:
19806442
[PubMed - indexed for MEDLINE]
4.

Human and rodent amyloid-beta peptides differentially bind heme: relevance to the human susceptibility to Alzheimer's disease.

Atamna H, Frey WH 2nd, Ko N.

Arch Biochem Biophys. 2009 Jul 1;487(1):59-65. doi: 10.1016/j.abb.2009.05.003. Epub 2009 May 18.

PMID:
19454279
[PubMed - indexed for MEDLINE]
5.

Heme-Cu bound aβ peptides: spectroscopic characterization, reactivity, and relevance to Alzheimer's disease.

Pramanik D, Ghosh C, Dey SG.

J Am Chem Soc. 2011 Oct 5;133(39):15545-52. doi: 10.1021/ja204628b. Epub 2011 Sep 13.

PMID:
21870836
[PubMed - indexed for MEDLINE]
6.

Amyloid beta-heme peroxidase promoted protein nitrotyrosination: relevance to widespread protein nitration in Alzheimer's disease.

Yuan C, Yi L, Yang Z, Deng Q, Huang Y, Li H, Gao Z.

J Biol Inorg Chem. 2012 Feb;17(2):197-207. doi: 10.1007/s00775-011-0842-3. Epub 2011 Sep 14.

PMID:
21915767
[PubMed - indexed for MEDLINE]
7.

Active site environment of heme-bound amyloid β peptide associated with Alzheimer's disease.

Pramanik D, Dey SG.

J Am Chem Soc. 2011 Jan 12;133(1):81-7. doi: 10.1021/ja1084578. Epub 2010 Dec 9.

PMID:
21141958
[PubMed - indexed for MEDLINE]
8.

Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review.

Butterfield DA.

Free Radic Res. 2002 Dec;36(12):1307-13. Review.

PMID:
12607822
[PubMed - indexed for MEDLINE]
9.

The mechanism for heme to prevent Aβ(1-40) aggregation and its cytotoxicity.

Bao Q, Luo Y, Li W, Sun X, Zhu C, Li P, Huang ZX, Tan X.

J Biol Inorg Chem. 2011 Jun;16(5):809-16. doi: 10.1007/s00775-011-0783-x. Epub 2011 Apr 27.

PMID:
21523435
[PubMed - indexed for MEDLINE]
10.

Aβ interacts with both the iron center and the porphyrin ring of heme: mechanism of heme's action on Aβ aggregation and disaggregation.

Yuan C, Gao Z.

Chem Res Toxicol. 2013 Feb 18;26(2):262-9. doi: 10.1021/tx300441e. Epub 2013 Jan 15.

PMID:
23289528
[PubMed - indexed for MEDLINE]
11.

Mechanisms of mitochondrial dysfunction and energy deficiency in Alzheimer's disease.

Atamna H, Frey WH 2nd.

Mitochondrion. 2007 Sep;7(5):297-310. Epub 2007 Jun 13. Review.

PMID:
17625988
[PubMed - indexed for MEDLINE]
12.

A role for heme in Alzheimer's disease: heme binds amyloid beta and has altered metabolism.

Atamna H, Frey WH 2nd.

Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):11153-8. Epub 2004 Jul 19.

PMID:
15263070
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Interaction between amyloid-β peptide and heme probed by electrochemistry and atomic force microscopy.

Zhou Y, Wang J, Liu L, Wang R, Lai X, Xu M.

ACS Chem Neurosci. 2013 Apr 17;4(4):535-9. doi: 10.1021/cn300231q. Epub 2013 Jan 24.

PMID:
23590249
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Aluminum, copper, iron and zinc differentially alter amyloid-Aβ(1-42) aggregation and toxicity.

Bolognin S, Messori L, Drago D, Gabbiani C, Cendron L, Zatta P.

Int J Biochem Cell Biol. 2011 Jun;43(6):877-85. doi: 10.1016/j.biocel.2011.02.009. Epub 2011 Mar 3.

PMID:
21376832
[PubMed - indexed for MEDLINE]
15.

The H63D HFE gene variant promotes activation of the intrinsic apoptotic pathway via mitochondria dysfunction following β-amyloid peptide exposure.

Mairuae N, Hall Ii EC, Cheepsunthorn P, Lee SY, Connor JR.

J Neurosci Res. 2010 Nov 1;88(14):3079-89. doi: 10.1002/jnr.22466.

PMID:
20734416
[PubMed - indexed for MEDLINE]
16.

Ternary complexes of iron, amyloid-beta, and nitrilotriacetic acid: binding affinities, redox properties, and relevance to iron-induced oxidative stress in Alzheimer's disease.

Jiang D, Li X, Williams R, Patel S, Men L, Wang Y, Zhou F.

Biochemistry. 2009 Aug 25;48(33):7939-47. doi: 10.1021/bi900907a.

PMID:
19601593
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Lipid oxidation and modification of amyloid-β (Aβ) in vitro and in vivo.

Ellis G, Fang E, Maheshwari M, Roltsch E, Holcomb L, Zimmer D, Martinez D, Murray IV.

J Alzheimers Dis. 2010;22(2):593-607. doi: 10.3233/JAD-2010-100960.

PMID:
20847409
[PubMed - indexed for MEDLINE]
18.

Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death.

Butterfield DA, Castegna A, Lauderback CM, Drake J.

Neurobiol Aging. 2002 Sep-Oct;23(5):655-64. Review.

PMID:
12392766
[PubMed - indexed for MEDLINE]
19.

Rodent Abeta(1-42) exhibits oxidative stress properties similar to those of human Abeta(1-42): Implications for proposed mechanisms of toxicity.

Boyd-Kimball D, Sultana R, Mohmmad-Abdul H, Butterfield DA.

J Alzheimers Dis. 2004 Oct;6(5):515-25.

PMID:
15505374
[PubMed - indexed for MEDLINE]
20.

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