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Items: 1 to 20 of 240

1.

Green tea polyphenols modulate insulin secretion by inhibiting glutamate dehydrogenase.

Li C, Allen A, Kwagh J, Doliba NM, Qin W, Najafi H, Collins HW, Matschinsky FM, Stanley CA, Smith TJ.

J Biol Chem. 2006 Apr 14;281(15):10214-21. Epub 2006 Feb 13.

2.

Effects of a GTP-insensitive mutation of glutamate dehydrogenase on insulin secretion in transgenic mice.

Li C, Matter A, Kelly A, Petty TJ, Najafi H, MacMullen C, Daikhin Y, Nissim I, Lazarow A, Kwagh J, Collins HW, Hsu BY, Nissim I, Yudkoff M, Matschinsky FM, Stanley CA.

J Biol Chem. 2006 Jun 2;281(22):15064-72. Epub 2006 Mar 30.

3.

Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets.

Carobbio S, Ishihara H, Fernandez-Pascual S, Bartley C, Martin-Del-Rio R, Maechler P.

Diabetologia. 2004 Feb;47(2):266-76. Epub 2003 Dec 20.

PMID:
14689183
4.

Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics.

Li M, Smith CJ, Walker MT, Smith TJ.

J Biol Chem. 2009 Aug 21;284(34):22988-3000. doi: 10.1074/jbc.M109.020222. Epub 2009 Jun 15.

6.

Glutaminolysis and insulin secretion: from bedside to bench and back.

Kelly A, Li C, Gao Z, Stanley CA, Matschinsky FM.

Diabetes. 2002 Dec;51 Suppl 3:S421-6.

7.

Regulation of leucine-stimulated insulin secretion and glutamine metabolism in isolated rat islets.

Li C, Najafi H, Daikhin Y, Nissim IB, Collins HW, Yudkoff M, Matschinsky FM, Stanley CA.

J Biol Chem. 2003 Jan 31;278(5):2853-8. Epub 2002 Nov 19.

8.

Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site.

Li C, Li M, Chen P, Narayan S, Matschinsky FM, Bennett MJ, Stanley CA, Smith TJ.

J Biol Chem. 2011 Sep 30;286(39):34164-74. doi: 10.1074/jbc.M111.268599. Epub 2011 Aug 3.

9.

Regulation of glutamate metabolism and insulin secretion by glutamate dehydrogenase in hypoglycemic children.

Stanley CA.

Am J Clin Nutr. 2009 Sep;90(3):862S-866S. doi: 10.3945/ajcn.2009.27462AA. Epub 2009 Jul 22. Review.

10.

Regulatory effects of 5'-deoxypyridoxal on glutamate dehydrogenase activity and insulin secretion in pancreatic islets.

Yang SJ, Huh JW, Kim MJ, Lee WJ, Kim TU, Choi SY, Cho SW.

Biochimie. 2003 Jun;85(6):581-6.

PMID:
12829375
11.

Overexpression of constitutively activated glutamate dehydrogenase induces insulin secretion through enhanced glutamate oxidation.

Anno T, Uehara S, Katagiri H, Ohta Y, Ueda K, Mizuguchi H, Moriyama Y, Oka Y, Tanizawa Y.

Am J Physiol Endocrinol Metab. 2004 Feb;286(2):E280-5. Epub 2003 Oct 7.

12.

High throughput screening reveals several new classes of glutamate dehydrogenase inhibitors.

Li M, Allen A, Smith TJ.

Biochemistry. 2007 Dec 25;46(51):15089-102. Epub 2007 Nov 29.

13.
14.

Glucose regulation of glutaminolysis and its role in insulin secretion.

Gao ZY, Li G, Najafi H, Wolf BA, Matschinsky FM.

Diabetes. 1999 Aug;48(8):1535-42.

PMID:
10426370
15.

Decreased insulin secretion in islets from protein malnourished rats is associated with impaired glutamate dehydrogenase function: effect of leucine supplementation.

da Silva PM, Batista TM, Ribeiro RA, Zoppi CC, Boschero AC, Carneiro EM.

Metabolism. 2012 May;61(5):721-32. doi: 10.1016/j.metabol.2011.09.012. Epub 2011 Nov 9.

16.

Inhibitory effects of Cimicifuga heracleifolia extract on glutamate formation and glutamate dehydrogenase activity in cultured islets.

Lee KH, Lee WJ, Yang SJ, Huh JW, Choi J, Hong HN, Hwang O, Cho SW.

Mol Cells. 2004 Jun 30;17(3):509-14. Erratum in: Mol Cells. 2004 Aug 31;18(1):131.

17.

Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations.

Fang J, Hsu BY, MacMullen CM, Poncz M, Smith TJ, Stanley CA.

Biochem J. 2002 Apr 1;363(Pt 1):81-7.

18.

Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.

Carobbio S, Frigerio F, Rubi B, Vetterli L, Bloksgaard M, Gjinovci A, Pournourmohammadi S, Herrera PL, Reith W, Mandrup S, Maechler P.

J Biol Chem. 2009 Jan 9;284(2):921-9. doi: 10.1074/jbc.M806295200. Epub 2008 Nov 17.

19.

Metabolic and ionic coupling factors in amino acid-stimulated insulin release in pancreatic beta-HC9 cells.

Doliba NM, Wehrli SL, Vatamaniuk MZ, Qin W, Buettger CW, Collins HW, Matschinsky FM.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1507-19. Epub 2007 Jan 30.

20.

Evolution of glutamate dehydrogenase regulation of insulin homeostasis is an example of molecular exaptation.

Allen A, Kwagh J, Fang J, Stanley CA, Smith TJ.

Biochemistry. 2004 Nov 16;43(45):14431-43.

PMID:
15533048
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