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Results: 1 to 20 of 242

1.

The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites.

Kapetanaki MG, Guerrero-Santoro J, Bisi DC, Hsieh CL, Rapić-Otrin V, Levine AS.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2588-93. Epub 2006 Feb 10.

PMID:
16473935
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A.

Guerrero-Santoro J, Kapetanaki MG, Hsieh CL, Gorbachinsky I, Levine AS, Rapić-Otrin V.

Cancer Res. 2008 Jul 1;68(13):5014-22. doi: 10.1158/0008-5472.CAN-07-6162.

PMID:
18593899
[PubMed - indexed for MEDLINE]
Free Article
3.

Monoubiquitinated histone H2A destabilizes photolesion-containing nucleosomes with concomitant release of UV-damaged DNA-binding protein E3 ligase.

Lan L, Nakajima S, Kapetanaki MG, Hsieh CL, Fagerburg M, Thickman K, Rodriguez-Collazo P, Leuba SH, Levine AS, Rapić-Otrin V.

J Biol Chem. 2012 Apr 6;287(15):12036-49. doi: 10.1074/jbc.M111.307058. Epub 2012 Feb 10.

PMID:
22334663
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

DDB2, the xeroderma pigmentosum group E gene product, is directly ubiquitylated by Cullin 4A-based ubiquitin ligase complex.

Matsuda N, Azuma K, Saijo M, Iemura S, Hioki Y, Natsume T, Chiba T, Tanaka K, Tanaka K.

DNA Repair (Amst). 2005 May 2;4(5):537-45.

PMID:
15811626
[PubMed - indexed for MEDLINE]
5.

DNA damage binding protein component DDB1 participates in nucleotide excision repair through DDB2 DNA-binding and cullin 4A ubiquitin ligase activity.

Li J, Wang QE, Zhu Q, El-Mahdy MA, Wani G, Praetorius-Ibba M, Wani AA.

Cancer Res. 2006 Sep 1;66(17):8590-7.

PMID:
16951172
[PubMed - indexed for MEDLINE]
Free Article
6.

DDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA.

Takedachi A, Saijo M, Tanaka K.

Mol Cell Biol. 2010 Jun;30(11):2708-23. doi: 10.1128/MCB.01460-09. Epub 2010 Apr 5.

PMID:
20368362
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Cullin 4A-mediated proteolysis of DDB2 protein at DNA damage sites regulates in vivo lesion recognition by XPC.

El-Mahdy MA, Zhu Q, Wang QE, Wani G, Praetorius-Ibba M, Wani AA.

J Biol Chem. 2006 May 12;281(19):13404-11. Epub 2006 Mar 8.

PMID:
16527807
[PubMed - indexed for MEDLINE]
Free Article
8.

Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair.

Yeh JI, Levine AS, Du S, Chinte U, Ghodke H, Wang H, Shi H, Hsieh CL, Conway JF, Van Houten B, Rapić-Otrin V.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):E2737-46. doi: 10.1073/pnas.1110067109. Epub 2012 Jul 20.

PMID:
22822215
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The xeroderma pigmentosum group E gene product DDB2 activates nucleotide excision repair by regulating the level of p21Waf1/Cip1.

Stoyanova T, Yoon T, Kopanja D, Mokyr MB, Raychaudhuri P.

Mol Cell Biol. 2008 Jan;28(1):177-87. Epub 2007 Oct 29.

PMID:
17967871
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

True XP group E patients have a defective UV-damaged DNA binding protein complex and mutations in DDB2 which reveal the functional domains of its p48 product.

Rapić-Otrin V, Navazza V, Nardo T, Botta E, McLenigan M, Bisi DC, Levine AS, Stefanini M.

Hum Mol Genet. 2003 Jul 1;12(13):1507-22.

PMID:
12812979
[PubMed - indexed for MEDLINE]
Free Article
11.

Cellular concentrations of DDB2 regulate dynamic binding of DDB1 at UV-induced DNA damage.

Alekseev S, Luijsterburg MS, Pines A, Geverts B, Mari PO, Giglia-Mari G, Lans H, Houtsmuller AB, Mullenders LH, Hoeijmakers JH, Vermeulen W.

Mol Cell Biol. 2008 Dec;28(24):7402-13. doi: 10.1128/MCB.01108-08. Epub 2008 Oct 20.

PMID:
18936169
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Relationship of the xeroderma pigmentosum group E DNA repair defect to the chromatin and DNA binding proteins UV-DDB and replication protein A.

Rapić Otrin V, Kuraoka I, Nardo T, McLenigan M, Eker AP, Stefanini M, Levine AS, Wood RD.

Mol Cell Biol. 1998 Jun;18(6):3182-90.

PMID:
9584159
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

DDB1-DDB2 (xeroderma pigmentosum group E) protein complex recognizes a cyclobutane pyrimidine dimer, mismatches, apurinic/apyrimidinic sites, and compound lesions in DNA.

Wittschieben BØ, Iwai S, Wood RD.

J Biol Chem. 2005 Dec 2;280(48):39982-9. Epub 2005 Aug 24.

PMID:
16223728
[PubMed - indexed for MEDLINE]
Free Article
15.

Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC.

Luijsterburg MS, Goedhart J, Moser J, Kool H, Geverts B, Houtsmuller AB, Mullenders LH, Vermeulen W, van Driel R.

J Cell Sci. 2007 Aug 1;120(Pt 15):2706-16. Epub 2007 Jul 17.

PMID:
17635991
[PubMed - indexed for MEDLINE]
Free Article
16.

UV-induced ubiquitylation of XPC complex, the UV-DDB-ubiquitin ligase complex, and DNA repair.

Sugasawa K.

J Mol Histol. 2006 Sep;37(5-7):189-202. Epub 2006 Jul 21. Review.

PMID:
16858626
[PubMed - indexed for MEDLINE]
17.

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.

Groisman R, Polanowska J, Kuraoka I, Sawada J, Saijo M, Drapkin R, Kisselev AF, Tanaka K, Nakatani Y.

Cell. 2003 May 2;113(3):357-67.

PMID:
12732143
[PubMed - indexed for MEDLINE]
18.

Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA.

Fei J, Kaczmarek N, Luch A, Glas A, Carell T, Naegeli H.

PLoS Biol. 2011 Oct;9(10):e1001183. doi: 10.1371/journal.pbio.1001183. Epub 2011 Oct 25.

PMID:
22039351
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein.

Tang J, Chu G.

DNA Repair (Amst). 2002 Aug 6;1(8):601-16. Review.

PMID:
12509284
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for efficient nucleotide excision repair.

Wang QE, Praetorius-Ibba M, Zhu Q, El-Mahdy MA, Wani G, Zhao Q, Qin S, Patnaik S, Wani AA.

Nucleic Acids Res. 2007;35(16):5338-50. Epub 2007 Aug 9.

PMID:
17693435
[PubMed - indexed for MEDLINE]
Free PMC Article
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