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Results: 1 to 20 of 189

1.

Statistical practice in high-throughput screening data analysis.

Malo N, Hanley JA, Cerquozzi S, Pelletier J, Nadon R.

Nat Biotechnol. 2006 Feb;24(2):167-75.

PMID:
16465162
[PubMed - indexed for MEDLINE]
2.

Development of multiplexed microarray binding assays for high-throughput drug discovery.

Hong Y, Liu L, Pai S, Graf JN, Rao H, Lynn JG, van Staden C, Lee PH, Lai F, Salon JA.

Assay Drug Dev Technol. 2009 Jun;7(3):281-93. doi: 10.1089/adt.2008.180.

PMID:
19604106
[PubMed - indexed for MEDLINE]
3.

Quantitative assessment of hit detection and confirmation in single and duplicate high-throughput screenings.

Wu Z, Liu D, Sui Y.

J Biomol Screen. 2008 Feb;13(2):159-67. doi: 10.1177/1087057107312628. Epub 2008 Jan 23.

PMID:
18216390
[PubMed - indexed for MEDLINE]
4.

An efficient method for the detection and elimination of systematic error in high-throughput screening.

Makarenkov V, Zentilli P, Kevorkov D, Gagarin A, Malo N, Nadon R.

Bioinformatics. 2007 Jul 1;23(13):1648-57. Epub 2007 Apr 26.

PMID:
17463024
[PubMed - indexed for MEDLINE]
Free Article
5.
6.

Integrated expressional analysis: application to the drug discovery process.

Ilyin SE, Horowitz D, Belkowski SM, Xin H, Eckardt AJ, Darrow AL, Chen C, Maley D, D'Andrea M, Plata-Salamán CR, Derian CK.

Methods. 2005 Nov;37(3):280-8.

PMID:
16308157
[PubMed - indexed for MEDLINE]
7.

Novel statistical approach for primary high-throughput screening hit selection.

Yan SF, Asatryan H, Li J, Zhou Y.

J Chem Inf Model. 2005 Nov-Dec;45(6):1784-90.

PMID:
16309285
[PubMed - indexed for MEDLINE]
8.

poolHiTS: a shifted transversal design based pooling strategy for high-throughput drug screening.

Kainkaryam RM, Woolf PJ.

BMC Bioinformatics. 2008 May 30;9:256. doi: 10.1186/1471-2105-9-256.

PMID:
18513431
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Identifying actives from HTS data sets: practical approaches for the selection of an appropriate HTS data-processing method and quality control review.

Shun TY, Lazo JS, Sharlow ER, Johnston PA.

J Biomol Screen. 2011 Jan;16(1):1-14. doi: 10.1177/1087057110389039. Epub 2010 Dec 15.

PMID:
21160066
[PubMed - indexed for MEDLINE]
10.

Integration of statistical inference methods and a novel control measure to improve sensitivity and specificity of data analysis in expression profiling studies.

Zang S, Guo R, Zhang L, Lu Y.

J Biomed Inform. 2007 Oct;40(5):552-60. Epub 2007 Jan 19.

PMID:
17317331
[PubMed - indexed for MEDLINE]
Free Article
11.

Designing screens: how to make your hits a hit.

Walters WP, Namchuk M.

Nat Rev Drug Discov. 2003 Apr;2(4):259-66. Review.

PMID:
12669025
[PubMed - indexed for MEDLINE]
12.

An improved beta-lactamase reporter assay: multiplexing with a cytotoxicity readout for enhanced accuracy of hit identification.

Hallis TM, Kopp AL, Gibson J, Lebakken CS, Hancock M, Van Den Heuvel-Kramer K, Turek-Etienne T.

J Biomol Screen. 2007 Aug;12(5):635-44. Epub 2007 May 21.

PMID:
17517902
[PubMed - indexed for MEDLINE]
13.

A Gibbs sampler for the identification of gene expression and network connectivity consistency.

Brynildsen MP, Tran LM, Liao JC.

Bioinformatics. 2006 Dec 15;22(24):3040-6. Epub 2006 Oct 23.

PMID:
17060361
[PubMed - indexed for MEDLINE]
Free Article
14.

Evaluating real-life high-throughput screening data.

Gribbon P, Lyons R, Laflin P, Bradley J, Chambers C, Williams BS, Keighley W, Sewing A.

J Biomol Screen. 2005 Mar;10(2):99-107.

PMID:
15799953
[PubMed - indexed for MEDLINE]
15.

Application of nearest-neighbor and cluster analyses in pharmaceutical lead discovery.

Stanton DT, Morris TW, Roychoudhury S, Parker CN.

J Chem Inf Comput Sci. 1999 Jan-Feb;39(1):21-7.

PMID:
9987851
[PubMed - indexed for MEDLINE]
16.

Some statistical issues in microarray gene expression data.

Mayo MS, Gajewski BJ, Morris JS.

Radiat Res. 2006 Jun;165(6):745-8.

PMID:
16802876
[PubMed - indexed for MEDLINE]
17.

Interpretation of uniform-well readouts.

Josiah S.

Methods Mol Biol. 2009;486:177-92. doi: 10.1007/978-1-60327-545-3_13.

PMID:
19347624
[PubMed - indexed for MEDLINE]
18.

Alternative statistical parameter for high-throughput screening assay quality assessment.

Sui Y, Wu Z.

J Biomol Screen. 2007 Mar;12(2):229-34. Epub 2007 Jan 11.

PMID:
17218666
[PubMed - indexed for MEDLINE]
19.

The application of high-throughput screening to novel lead discovery.

Kenny BA, Bushfield M, Parry-Smith DJ, Fogarty S, Treherne JM.

Prog Drug Res. 1998;51:245-69. Review.

PMID:
9949864
[PubMed - indexed for MEDLINE]
20.

Improving the design and analysis of high-throughput screening technology comparison experiments using statistical modeling.

Woodward PW, Williams C, Sewing A, Benson N.

J Biomol Screen. 2006 Feb;11(1):5-12. Epub 2005 Oct 18.

PMID:
16234338
[PubMed - indexed for MEDLINE]

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