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Items: 1 to 20 of 112

1.

Pol II-expressed shRNA knocks down Sod2 gene expression and causes phenotypes of the gene knockout in mice.

Xia XG, Zhou H, Samper E, Melov S, Xu Z.

PLoS Genet. 2006 Jan;2(1):e10. Epub 2006 Jan 27.

3.

Construction of simple and efficient DNA vector-based short hairpin RNA expression systems for specific gene silencing in mammalian cells.

Cheng TL, Chang WT.

Methods Mol Biol. 2007;408:223-41. doi: 10.1007/978-1-59745-547-3_13.

PMID:
18314586
4.

Production of transgenic pigs that express porcine endogenous retrovirus small interfering RNAs.

Ramsoondar J, Vaught T, Ball S, Mendicino M, Monahan J, Jobst P, Vance A, Duncan J, Wells K, Ayares D.

Xenotransplantation. 2009 May-Jun;16(3):164-80. doi: 10.1111/j.1399-3089.2009.00525.x.

PMID:
19566656
5.

Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic.

Giering JC, Grimm D, Storm TA, Kay MA.

Mol Ther. 2008 Sep;16(9):1630-6. doi: 10.1038/mt.2008.144. Epub 2008 Jul 29.

PMID:
18665161
6.

Characterisation and application of a bovine U6 promoter for expression of short hairpin RNAs.

Lambeth LS, Moore RJ, Muralitharan M, Dalrymple BP, McWilliam S, Doran TJ.

BMC Biotechnol. 2005 May 11;5:13.

7.

Optimization and comparison of knockdown efficacy between polymerase II expressed shRNA and artificial miRNA targeting luciferase and Apolipoprotein B100.

Maczuga P, Koornneef A, Borel F, Petry H, van Deventer S, Ritsema T, Konstantinova P.

BMC Biotechnol. 2012 Jul 24;12:42. doi: 10.1186/1472-6750-12-42.

8.

An enhanced U6 promoter for synthesis of short hairpin RNA.

Xia XG, Zhou H, Ding H, Affar el B, Shi Y, Xu Z.

Nucleic Acids Res. 2003 Sep 1;31(17):e100.

9.

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways.

Grimm D, Streetz KL, Jopling CL, Storm TA, Pandey K, Davis CR, Marion P, Salazar F, Kay MA.

Nature. 2006 May 25;441(7092):537-41.

PMID:
16724069
10.

miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction.

Guda S, Brendel C, Renella R, Du P, Bauer DE, Canver MC, Grenier JK, Grimson AW, Kamran SC, Thornton J, de Boer H, Root DE, Milsom MD, Orkin SH, Gregory RI, Williams DA.

Mol Ther. 2015 Sep;23(9):1465-74. doi: 10.1038/mt.2015.113. Epub 2015 Jun 17.

PMID:
26080908
11.
12.

Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis.

Ding H, Schwarz DS, Keene A, Affar el B, Fenton L, Xia X, Shi Y, Zamore PD, Xu Z.

Aging Cell. 2003 Aug;2(4):209-17.

PMID:
12934714
13.

Comparison of chicken 7SK and U6 RNA polymerase III promoters for short hairpin RNA expression.

Bannister SC, Wise TG, Cahill DM, Doran TJ.

BMC Biotechnol. 2007 Nov 19;7:79.

14.

A quick and efficient approach for gene silencing by using triple putative microRNA-based short hairpin RNAs.

Shan ZX, Lin QX, Yang M, Deng CY, Kuang SJ, Zhou ZL, Xiao DZ, Liu XY, Lin SG, Yu XY.

Mol Cell Biochem. 2009 Mar;323(1-2):81-9. doi: 10.1007/s11010-008-9966-3. Epub 2008 Nov 27.

PMID:
19037714
15.

Target validation in mice by constitutive and conditional RNAi.

Kleinhammer A, Wurst W, Kühn R.

Methods Mol Biol. 2013;986:307-23. doi: 10.1007/978-1-62703-311-4_19.

PMID:
23436420
16.

Inhibition of HIV-1 replication with designed miRNAs expressed from RNA polymerase II promoters.

Lo HL, Chang T, Yam P, Marcovecchio PM, Li S, Zaia JA, Yee JK.

Gene Ther. 2007 Nov;14(21):1503-12. Epub 2007 Sep 6.

PMID:
17805304
17.

shRNA transcribed by RNA Pol II promoter induce RNA interference in mammalian cell.

Yuan J, Wang X, Zhang Y, Hu X, Deng X, Fei J, Li N.

Mol Biol Rep. 2006 Mar;33(1):43-9.

PMID:
16636916
18.

A miR-21 hairpin structure-based gene knockdown vector.

Yue J, Sheng Y, Ren A, Penmatsa S.

Biochem Biophys Res Commun. 2010 Apr 9;394(3):667-72. doi: 10.1016/j.bbrc.2010.03.047. Epub 2010 Mar 11.

19.

Reproducible and inducible knockdown of gene expression in mice.

Yu J, McMahon AP.

Genesis. 2006 May;44(5):252-61.

PMID:
16676321
20.

Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype.

Kunath T, Gish G, Lickert H, Jones N, Pawson T, Rossant J.

Nat Biotechnol. 2003 May;21(5):559-61. Epub 2003 Apr 7.

PMID:
12679785
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