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Results: 1 to 20 of 105

1.

Assessing the clinical significance of botanical supplementation on human cytochrome P450 3A activity: comparison of a milk thistle and black cohosh product to rifampin and clarithromycin.

Gurley B, Hubbard MA, Williams DK, Thaden J, Tong Y, Gentry WB, Breen P, Carrier DJ, Cheboyina S.

J Clin Pharmacol. 2006 Feb;46(2):201-13.

PMID:
16432272
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Effect of milk thistle (Silybum marianum) and black cohosh (Cimicifuga racemosa) supplementation on digoxin pharmacokinetics in humans.

Gurley BJ, Barone GW, Williams DK, Carrier J, Breen P, Yates CR, Song PF, Hubbard MA, Tong Y, Cheboyina S.

Drug Metab Dispos. 2006 Jan;34(1):69-74. Epub 2005 Oct 12.

PMID:
16221754
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto.

Gurley BJ, Gardner SF, Hubbard MA, Williams DK, Gentry WB, Carrier J, Khan IA, Edwards DJ, Shah A.

Clin Pharmacol Ther. 2004 Nov;76(5):428-40. Erratum in: Clin Pharmacol Ther. 2005 May;77(5):456.

PMID:
15536458
[PubMed - indexed for MEDLINE]
4.

In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 phenotypes.

Gurley BJ, Gardner SF, Hubbard MA, Williams DK, Gentry WB, Khan IA, Shah A.

Clin Pharmacol Ther. 2005 May;77(5):415-26.

PMID:
15900287
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity.

Gorski JC, Vannaprasaht S, Hamman MA, Ambrosius WT, Bruce MA, Haehner-Daniels B, Hall SD.

Clin Pharmacol Ther. 2003 Sep;74(3):275-87. Erratum in: Clin Pharmacol Ther. 2004 Mar;75(3):249.

PMID:
12966371
[PubMed - indexed for MEDLINE]
6.

Effect of goldenseal (Hydrastis canadensis) and kava kava (Piper methysticum) supplementation on digoxin pharmacokinetics in humans.

Gurley BJ, Swain A, Barone GW, Williams DK, Breen P, Yates CR, Stuart LB, Hubbard MA, Tong Y, Cheboyina S.

Drug Metab Dispos. 2007 Feb;35(2):240-5. Epub 2006 Nov 1.

PMID:
17079360
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Physiologically based pharmacokinetic model of mechanism-based inhibition of CYP3A by clarithromycin.

Quinney SK, Zhang X, Lucksiri A, Gorski JC, Li L, Hall SD.

Drug Metab Dispos. 2010 Feb;38(2):241-8. doi: 10.1124/dmd.109.028746. Epub 2009 Nov 2.

PMID:
19884323
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics.

Gurley BJ, Swain A, Williams DK, Barone G, Battu SK.

Mol Nutr Food Res. 2008 Jul;52(7):772-9. doi: 10.1002/mnfr.200700081.

PMID:
18214850
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea.

Gurley BJ, Swain A, Hubbard MA, Williams DK, Barone G, Hartsfield F, Tong Y, Carrier DJ, Cheboyina S, Battu SK.

Mol Nutr Food Res. 2008 Jul;52(7):755-63. doi: 10.1002/mnfr.200600300.

PMID:
18214849
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Supplementation with goldenseal (Hydrastis canadensis), but not kava kava (Piper methysticum), inhibits human CYP3A activity in vivo.

Gurley BJ, Swain A, Hubbard MA, Hartsfield F, Thaden J, Williams DK, Gentry WB, Tong Y.

Clin Pharmacol Ther. 2008 Jan;83(1):61-9. Epub 2007 May 9.

PMID:
17495878
[PubMed - indexed for MEDLINE]
11.

Rifampin drastically reduces plasma concentrations and effects of oral midazolam.

Backman JT, Olkkola KT, Neuvonen PJ.

Clin Pharmacol Ther. 1996 Jan;59(1):7-13.

PMID:
8549036
[PubMed - indexed for MEDLINE]
12.

The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin.

Backman JT, Kivistö KT, Olkkola KT, Neuvonen PJ.

Eur J Clin Pharmacol. 1998 Mar;54(1):53-8.

PMID:
9591931
[PubMed - indexed for MEDLINE]
13.

Single-point sampling for assessment of constitutive, induced, and inhibited cytochrome P450 3A activity with alfentanil or midazolam.

Chaobal HN, Kharasch ED.

Clin Pharmacol Ther. 2005 Nov;78(5):529-39.

PMID:
16321619
[PubMed - indexed for MEDLINE]
14.

A systematic approach to evaluate herb-drug interaction mechanisms: investigation of milk thistle extracts and eight isolated constituents as CYP3A inhibitors.

Brantley SJ, Graf TN, Oberlies NH, Paine MF.

Drug Metab Dispos. 2013 Sep;41(9):1662-70. doi: 10.1124/dmd.113.052563. Epub 2013 Jun 25.

PMID:
23801821
[PubMed - indexed for MEDLINE]
15.

The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin.

Gorski JC, Jones DR, Haehner-Daniels BD, Hamman MA, O'Mara EM Jr, Hall SD.

Clin Pharmacol Ther. 1998 Aug;64(2):133-43.

PMID:
9728893
[PubMed - indexed for MEDLINE]
16.

Pregnane X receptor-mediated induction of Cyp3a by black cohosh.

Pang X, Cheng J, Krausz KW, Guo DA, Gonzalez FJ.

Xenobiotica. 2011 Feb;41(2):112-23. doi: 10.3109/00498254.2010.527021. Epub 2010 Oct 27.

PMID:
20979450
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Triazolam is ineffective in patients taking rifampin.

Villikka K, Kivistö KT, Backman JT, Olkkola KT, Neuvonen PJ.

Clin Pharmacol Ther. 1997 Jan;61(1):8-14.

PMID:
9024169
[PubMed - indexed for MEDLINE]
18.

Rifampin, a cytochrome P450 3A inducer, decreases plasma concentrations of antipsychotic risperidone in healthy volunteers.

Mahatthanatrakul W, Nontaput T, Ridtitid W, Wongnawa M, Sunbhanich M.

J Clin Pharm Ther. 2007 Apr;32(2):161-7.

PMID:
17381666
[PubMed - indexed for MEDLINE]
19.

Paradoxical role of cytochrome P450 3A in the bioactivation and clinical effects of levo-alpha-acetylmethadol: importance of clinical investigations to validate in vitro drug metabolism studies.

Kharasch ED, Whittington D, Hoffer C, Krudys K, Craig K, Vicini P, Sheffels P, Lalovic B.

Clin Pharmacokinet. 2005;44(7):731-51.

PMID:
15966756
[PubMed - indexed for MEDLINE]
20.

Midazolam and cortisol metabolism before and after CYP3A induction in humans.

Eeckhoudt SL, Desager JP, Robert AR, Leclercq I, Verbeeck RK, Horsmans Y.

Int J Clin Pharmacol Ther. 2001 Jul;39(7):293-9.

PMID:
11471773
[PubMed - indexed for MEDLINE]

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