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Results: 1 to 20 of 104

1.

UDP-glucuronosyltransferase 1A6: structural, functional, and regulatory aspects.

Bock KW, Köhle C.

Methods Enzymol. 2005;400:57-75. Review.

PMID:
16399343
[PubMed - indexed for MEDLINE]
2.

UDP-glucuronosyltransferases (UGTs): from purification of Ah-receptor-inducible UGT1A6 to coordinate regulation of subsets of CYPs, UGTs, and ABC transporters by nuclear receptors.

Bock KW, Bock-Hennig BS.

Drug Metab Rev. 2010 Feb;42(1):6-13. doi: 10.3109/03602530903205492. Review.

PMID:
19831498
[PubMed - indexed for MEDLINE]
3.

AH receptor-controlled transcriptional regulation and function of rat and human UDP-glucuronosyltransferase isoforms.

Bock KW, Gschaidmeier H, Heel H, Lehmköster T, Münzel PA, Raschko F, Bock-Hennig B.

Adv Enzyme Regul. 1998;38:207-22.

PMID:
9762354
[PubMed - indexed for MEDLINE]
4.

Functions and transcriptional regulation of PAH-inducible human UDP-glucuronosyltransferases.

Bock KW, Gschaidmeier H, Heel H, Lehmköster T, Münzel PA, Bock-Hennig BS.

Drug Metab Rev. 1999 May;31(2):411-22. Review.

PMID:
10335444
[PubMed - indexed for MEDLINE]
5.

Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus.

Strassburg CP, Strassburg A, Nguyen N, Li Q, Manns MP, Tukey RH.

Biochem J. 1999 Mar 1;338 ( Pt 2):489-98.

PMID:
10024527
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Involvement of hepatocyte nuclear factor 1 in the regulation of the UDP-glucuronosyltransferase 1A7 (UGT1A7) gene in rat hepatocytes.

Metz RP, Auyeung DJ, Kessler FK, Ritter JK.

Mol Pharmacol. 2000 Aug;58(2):319-27.

PMID:
10908299
[PubMed - indexed for MEDLINE]
Free Article
7.

Evaluation of 5-hydroxytryptophol and other endogenous serotonin (5-hydroxytryptamine) analogs as substrates for UDP-glucuronosyltransferase 1A6.

Krishnaswamy S, Hao Q, Von Moltke LL, Greenblatt DJ, Court MH.

Drug Metab Dispos. 2004 Aug;32(8):862-9.

PMID:
15258112
[PubMed - indexed for MEDLINE]
Free Article
8.

Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate.

King CD, Rios GR, Assouline JA, Tephly TR.

Arch Biochem Biophys. 1999 May 1;365(1):156-62.

PMID:
10222050
[PubMed - indexed for MEDLINE]
9.

Aryl hydrocarbon receptor-inducible or constitutive expression of human UDP glucuronosyltransferase UGT1A6.

Münzel PA, Lehmköster T, Brück M, Ritter JK, Bock KW.

Arch Biochem Biophys. 1998 Feb 1;350(1):72-8.

PMID:
9466822
[PubMed - indexed for MEDLINE]
10.

Differential regulation of alternate UDP-glucuronosyltransferase 1A6 gene promoters by hepatic nuclear factor-1.

Auyeung DJ, Kessler FK, Ritter JK.

Toxicol Appl Pharmacol. 2003 Sep 1;191(2):156-66.

PMID:
12946651
[PubMed - indexed for MEDLINE]
11.

An alternative promoter contributes to tissue- and inducer-specific expression of the rat UDP-glucuronosyltransferase 1A6 gene.

Auyeung DJ, Kessler FK, Ritter JK.

Toxicol Appl Pharmacol. 2001 Jul 1;174(1):60-8.

PMID:
11437649
[PubMed - indexed for MEDLINE]
12.

Contribution of the Ah receptor to the phenolic antioxidant-mediated expression of human and rat UDP-glucuronosyltransferase UGT1A6 in Caco-2 and rat hepatoma 5L cells.

Münzel PA, Schmohl S, Buckler F, Jaehrling J, Raschko FT, Köhle C, Bock KW.

Biochem Pharmacol. 2003 Sep 1;66(5):841-7.

PMID:
12948865
[PubMed - indexed for MEDLINE]
13.

UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: I. Identification of polymorphisms in the 5'-regulatory and exon 1 regions, and association with human liver UGT1A6 gene expression and glucuronidation.

Krishnaswamy S, Hao Q, Al-Rohaimi A, Hesse LM, von Moltke LL, Greenblatt DJ, Court MH.

J Pharmacol Exp Ther. 2005 Jun;313(3):1331-9. Epub 2005 Mar 10.

PMID:
15761114
[PubMed - indexed for MEDLINE]
Free Article
14.

Expression and inducibility of UDP-glucuronosyltransferase 1As in MCF-7 human breast carcinoma cells.

Hanioka N, Iwabu H, Hanafusa H, Nakada S, Narimatsu S.

Basic Clin Pharmacol Toxicol. 2012 Mar;110(3):253-8. doi: 10.1111/j.1742-7843.2011.00790.x. Epub 2011 Oct 10.

PMID:
21902811
[PubMed - indexed for MEDLINE]
15.

Induction of rat UDP-glucuronosyltransferases in liver and duodenum by microsomal enzyme inducers that activate various transcriptional pathways.

Shelby MK, Klaassen CD.

Drug Metab Dispos. 2006 Oct;34(10):1772-8. Epub 2006 Jul 19.

PMID:
16855052
[PubMed - indexed for MEDLINE]
Free Article
16.

Interaction between oxidative stress sensor Nrf2 and xenobiotic-activated aryl hydrocarbon receptor in the regulation of the human phase II detoxifying UDP-glucuronosyltransferase 1A10.

Kalthoff S, Ehmer U, Freiberg N, Manns MP, Strassburg CP.

J Biol Chem. 2010 Feb 26;285(9):5993-6002. doi: 10.1074/jbc.M109.075770. Epub 2010 Jan 6.

PMID:
20053997
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Polymorphic expression of the UDP-glucuronosyltransferase UGT1A gene locus in human gastric epithelium.

Strassburg CP, Nguyen N, Manns MP, Tukey RH.

Mol Pharmacol. 1998 Oct;54(4):647-54.

PMID:
9765507
[PubMed - indexed for MEDLINE]
Free Article
18.

Characterization of benzo(a)pyrene-trans-7,8-dihydrodiol glucuronidation by human tissue microsomes and overexpressed UDP-glucuronosyltransferase enzymes.

Fang JL, Beland FA, Doerge DR, Wiener D, Guillemette C, Marques MM, Lazarus P.

Cancer Res. 2002 Apr 1;62(7):1978-86. Erratum in: Cancer Res 2002 Jun 1;62(11):3328.

PMID:
11929814
[PubMed - indexed for MEDLINE]
Free Article
19.

Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine.

Strassburg CP, Kneip S, Topp J, Obermayer-Straub P, Barut A, Tukey RH, Manns MP.

J Biol Chem. 2000 Nov 17;275(46):36164-71.

PMID:
10748067
[PubMed - indexed for MEDLINE]
Free Article
20.

Role for protein kinase C delta in the functional activity of human UGT1A6: implications for drug-drug interactions between PKC inhibitors and UGT1A6.

Volak LP, Court MH.

Xenobiotica. 2010 May;40(5):306-18. doi: 10.3109/00498251003596817.

PMID:
20196639
[PubMed - indexed for MEDLINE]

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