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Results: 1 to 20 of 124

1.

PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication.

Arias EE, Walter JC.

Nat Cell Biol. 2006 Jan;8(1):84-90. Epub 2005 Dec 18.

PMID:
16362051
[PubMed - indexed for MEDLINE]
2.
3.

L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage.

Higa LA, Banks D, Wu M, Kobayashi R, Sun H, Zhang H.

Cell Cycle. 2006 Aug;5(15):1675-80. Epub 2006 Aug 1.

PMID:
16861906
[PubMed - indexed for MEDLINE]
Free Article
4.

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

Nishitani H, Sugimoto N, Roukos V, Nakanishi Y, Saijo M, Obuse C, Tsurimoto T, Nakayama KI, Nakayama K, Fujita M, Lygerou Z, Nishimoto T.

EMBO J. 2006 Mar 8;25(5):1126-36. Epub 2006 Feb 16.

PMID:
16482215
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

Jin J, Arias EE, Chen J, Harper JW, Walter JC.

Mol Cell. 2006 Sep 1;23(5):709-21.

PMID:
16949367
[PubMed - indexed for MEDLINE]
Free Article
6.

Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts.

Arias EE, Walter JC.

Genes Dev. 2005 Jan 1;19(1):114-26. Epub 2004 Dec 14.

PMID:
15598982
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Proliferating cell nuclear antigen recruits cyclin-dependent kinase inhibitor Xic1 to DNA and couples its proteolysis to DNA polymerase switching.

Chuang LC, Yew PR.

J Biol Chem. 2005 Oct 21;280(42):35299-309. Epub 2005 Aug 23.

PMID:
16118211
[PubMed - indexed for MEDLINE]
Free Article
8.

PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination.

Senga T, Sivaprasad U, Zhu W, Park JH, Arias EE, Walter JC, Dutta A.

J Biol Chem. 2006 Mar 10;281(10):6246-52. Epub 2006 Jan 9.

PMID:
16407252
[PubMed - indexed for MEDLINE]
Free Article
9.

Repression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts.

Tsuyama T, Watanabe S, Aoki A, Cho Y, Seki M, Enomoto T, Tada S.

Mol Biol Cell. 2009 Feb;20(3):937-47. doi: 10.1091/mbc.E08-06-0613. Epub 2008 Dec 8.

PMID:
19064889
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Docking of a specialized PIP Box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4Cdt2.

Havens CG, Walter JC.

Mol Cell. 2009 Jul 10;35(1):93-104. doi: 10.1016/j.molcel.2009.05.012.

PMID:
19595719
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus.

Lutzmann M, Maiorano D, M├ęchali M.

EMBO J. 2006 Dec 13;25(24):5764-74. Epub 2006 Nov 23.

PMID:
17124498
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

One ring to rule them all? Another cellular responsibility for PCNA.

Green CM.

Trends Mol Med. 2006 Oct;12(10):455-8. Epub 2006 Aug 22.

PMID:
16931160
[PubMed - indexed for MEDLINE]
13.

Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts.

Tsuyama T, Tada S, Watanabe S, Seki M, Enomoto T.

Nucleic Acids Res. 2005 Feb 1;33(2):765-75. Print 2005.

PMID:
15687385
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Two different replication factor C proteins, Ctf18 and RFC1, separately control PCNA-CRL4Cdt2-mediated Cdt1 proteolysis during S phase and following UV irradiation.

Shiomi Y, Hayashi A, Ishii T, Shinmyozu K, Nakayama J, Sugasawa K, Nishitani H.

Mol Cell Biol. 2012 Jun;32(12):2279-88. doi: 10.1128/MCB.06506-11. Epub 2012 Apr 9.

PMID:
22493068
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Cell type-dependent requirement for PIP box-regulated Cdt1 destruction during S phase.

Lee HO, Zacharek SJ, Xiong Y, Duronio RJ.

Mol Biol Cell. 2010 Nov 1;21(21):3639-53. doi: 10.1091/mbc.E10-02-0130. Epub 2010 Sep 8.

PMID:
20826610
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Dynamic recruitment of licensing factor Cdt1 to sites of DNA damage.

Roukos V, Kinkhabwala A, Colombelli J, Kotsantis P, Taraviras S, Nishitani H, Stelzer E, Bastiaens P, Lygerou Z.

J Cell Sci. 2011 Feb 1;124(Pt 3):422-34. doi: 10.1242/jcs.074229. Epub 2011 Jan 11.

PMID:
21224399
[PubMed - indexed for MEDLINE]
Free Article
17.

A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction.

Raman M, Havens CG, Walter JC, Harper JW.

Mol Cell. 2011 Oct 7;44(1):72-84. doi: 10.1016/j.molcel.2011.06.036.

PMID:
21981919
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Inter-origin cooperativity of geminin action establishes an all-or-none switch for replication origin licensing.

Ode KL, Fujimoto K, Kubota Y, Takisawa H.

Genes Cells. 2011 Apr;16(4):380-96. doi: 10.1111/j.1365-2443.2011.01501.x.

PMID:
21426446
[PubMed - indexed for MEDLINE]
19.

Human Cdt1 lacking the evolutionarily conserved region that interacts with MCM2-7 is capable of inducing re-replication.

Teer JK, Dutta A.

J Biol Chem. 2008 Mar 14;283(11):6817-25. doi: 10.1074/jbc.M708767200. Epub 2008 Jan 8.

PMID:
18184650
[PubMed - indexed for MEDLINE]
Free Article
20.

Recombinant Cdt1 induces rereplication of G2 nuclei in Xenopus egg extracts.

Maiorano D, Krasinska L, Lutzmann M, Mechali M.

Curr Biol. 2005 Jan 26;15(2):146-53.

PMID:
15668171
[PubMed - indexed for MEDLINE]

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