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Results: 1 to 20 of 114

1.

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.

Martens S, Parvanova I, Zerrahn J, Griffiths G, Schell G, Reichmann G, Howard JC.

PLoS Pathog. 2005 Nov;1(3):e24. Epub 2005 Nov 18.

PMID:
16304607
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii.

Pawlowski N, Khaminets A, Hunn JP, Papic N, Schmidt A, Uthaiah RC, Lange R, Vopper G, Martens S, Wolf E, Howard JC.

BMC Biol. 2011 Jan 28;9:7. doi: 10.1186/1741-7007-9-7.

PMID:
21276251
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The gamma interferon (IFN-gamma)-inducible GTP-binding protein IGTP is necessary for toxoplasma vacuolar disruption and induces parasite egression in IFN-gamma-stimulated astrocytes.

Melzer T, Duffy A, Weiss LM, Halonen SK.

Infect Immun. 2008 Nov;76(11):4883-94. doi: 10.1128/IAI.01288-07. Epub 2008 Sep 2.

PMID:
18765738
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death.

Zhao YO, Khaminets A, Hunn JP, Howard JC.

PLoS Pathog. 2009 Feb;5(2):e1000288. doi: 10.1371/journal.ppat.1000288. Epub 2009 Feb 6.

PMID:
19197351
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Autophagic elimination of intracellular parasites: convergent induction by IFN-gamma and CD40 ligation?

Yap GS, Ling Y, Zhao Y.

Autophagy. 2007 Mar-Apr;3(2):163-5. Epub 2007 Mar 5.

PMID:
17204853
[PubMed - indexed for MEDLINE]
Free Article
6.

In astrocytes the accumulation of the immunity-related GTPases Irga6 and Irgb6 at the vacuole of Toxoplasma gondii is dependent on the parasite virulence.

Lubitz FP, Degrandi D, Pfeffer K, Mausberg AK.

ScientificWorldJournal. 2013 Nov 12;2013:480231. doi: 10.1155/2013/480231. eCollection 2013.

PMID:
24324375
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages.

Ling YM, Shaw MH, Ayala C, Coppens I, Taylor GA, Ferguson DJ, Yap GS.

J Exp Med. 2006 Sep 4;203(9):2063-71. Epub 2006 Aug 28.

PMID:
16940170
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages.

Zhao Y, Ferguson DJ, Wilson DC, Howard JC, Sibley LD, Yap GS.

J Immunol. 2009 Mar 15;182(6):3775-81. doi: 10.4049/jimmunol.0804190.

PMID:
19265156
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

p47 GTPases regulate Toxoplasma gondii survival in activated macrophages.

Butcher BA, Greene RI, Henry SC, Annecharico KL, Weinberg JB, Denkers EY, Sher A, Taylor GA.

Infect Immun. 2005 Jun;73(6):3278-86.

PMID:
15908352
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Role of autophagy in the host defense against Toxoplasma gondii in astrocytes.

Halonen SK.

Autophagy. 2009 Feb;5(2):268-9. Epub 2009 Feb 17.

PMID:
19139630
[PubMed - indexed for MEDLINE]
Free Article
11.

Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it.

Virreira Winter S, Niedelman W, Jensen KD, Rosowski EE, Julien L, Spooner E, Caradonna K, Burleigh BA, Saeij JP, Ploegh HL, Frickel EM.

PLoS One. 2011;6(9):e24434. doi: 10.1371/journal.pone.0024434. Epub 2011 Sep 8.

PMID:
21931713
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Biogenesis of and activities at the Toxoplasma gondii parasitophorous vacuole membrane.

Sinai AP.

Subcell Biochem. 2008;47:155-64. Review.

PMID:
18512349
[PubMed - indexed for MEDLINE]
13.

A cluster of interferon-γ-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii.

Yamamoto M, Okuyama M, Ma JS, Kimura T, Kamiyama N, Saiga H, Ohshima J, Sasai M, Kayama H, Okamoto T, Huang DC, Soldati-Favre D, Horie K, Takeda J, Takeda K.

Immunity. 2012 Aug 24;37(2):302-13. Epub 2012 Jul 12.

PMID:
22795875
[PubMed - indexed for MEDLINE]
Free Article
14.

Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii.

Steinfeldt T, Könen-Waisman S, Tong L, Pawlowski N, Lamkemeyer T, Sibley LD, Hunn JP, Howard JC.

PLoS Biol. 2010 Dec 21;8(12):e1000576. doi: 10.1371/journal.pbio.1000576.

PMID:
21203588
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Toxoplasma gondii and the Immunity-Related GTPase (IRG) resistance system in mice: a review.

Zhao YO, Rohde C, Lilue JT, Könen-Waisman S, Khaminets A, Hunn JP, Howard JC.

Mem Inst Oswaldo Cruz. 2009 Mar;104(2):234-40. Review.

PMID:
19430648
[PubMed - indexed for MEDLINE]
Free Article
16.

Interferon-γ restricts Toxoplasma gondii development in murine skeletal muscle cells via nitric oxide production and immunity-related GTPases.

Takács AC, Swierzy IJ, Lüder CG.

PLoS One. 2012;7(9):e45440. Epub 2012 Sep 14.

PMID:
23024821
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP.

Halonen SK, Taylor GA, Weiss LM.

Infect Immun. 2001 Sep;69(9):5573-6.

PMID:
11500431
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens.

Liesenfeld O, Parvanova I, Zerrahn J, Han SJ, Heinrich F, Muñoz M, Kaiser F, Aebischer T, Buch T, Waisman A, Reichmann G, Utermöhlen O, von Stebut E, von Loewenich FD, Bogdan C, Specht S, Saeftel M, Hoerauf A, Mota MM, Könen-Waisman S, Kaufmann SH, Howard JC.

PLoS One. 2011;6(6):e20568. doi: 10.1371/journal.pone.0020568. Epub 2011 Jun 17.

PMID:
21698150
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Role of mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii.

Ohshima J, Lee Y, Sasai M, Saitoh T, Su Ma J, Kamiyama N, Matsuura Y, Pann-Ghill S, Hayashi M, Ebisu S, Takeda K, Akira S, Yamamoto M.

J Immunol. 2014 Apr 1;192(7):3328-35. doi: 10.4049/jimmunol.1302822. Epub 2014 Feb 21.

PMID:
24563254
[PubMed - indexed for MEDLINE]
20.

A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1) in mouse liver.

Zeng J, Parvanova IA, Howard JC.

PLoS One. 2009 Aug 26;4(8):e6787. doi: 10.1371/journal.pone.0006787.

PMID:
20368812
[PubMed - indexed for MEDLINE]
Free PMC Article

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