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Results: 1 to 20 of 247

1.

Tetanus toxin fragment C fusion facilitates protein delivery to CNS neurons from cerebrospinal fluid in mice.

Benn SC, Ay I, Bastia E, Chian RJ, Celia SA, Pepinsky RB, Fishman PS, Brown RH Jr, Francis JW.

J Neurochem. 2005 Nov;95(4):1118-31.

PMID:
16271047
[PubMed - indexed for MEDLINE]
2.

A glial cell line-derived neurotrophic factor (GDNF):tetanus toxin fragment C protein conjugate improves delivery of GDNF to spinal cord motor neurons in mice.

Larsen KE, Benn SC, Ay I, Chian RJ, Celia SA, Remington MP, Bejarano M, Liu M, Ross J, Carmillo P, Sah D, Phillips KA, Sulzer D, Pepinsky RB, Fishman PS, Brown RH Jr, Francis JW.

Brain Res. 2006 Nov 20;1120(1):1-12. Epub 2006 Oct 3.

PMID:
17020749
[PubMed - indexed for MEDLINE]
3.

IGF-1:tetanus toxin fragment C fusion protein improves delivery of IGF-1 to spinal cord but fails to prolong survival of ALS mice.

Chian RJ, Li J, Ay I, Celia SA, Kashi BB, Tamrazian E, Matthews JC, Bronson RT, Rossomando A, Pepinsky RB, Fishman PS, Brown RH Jr, Francis JW.

Brain Res. 2009 Sep 1;1287:1-19. doi: 10.1016/j.brainres.2009.06.066. Epub 2009 Jun 27.

PMID:
19563785
[PubMed - indexed for MEDLINE]
4.

Tetanus toxin fragment C as a vector to enhance delivery of proteins to the CNS.

Francis JW, Bastia E, Matthews CC, Parks DA, Schwarzschild MA, Brown RH Jr, Fishman PS.

Brain Res. 2004 Jun 11;1011(1):7-13.

PMID:
15140640
[PubMed - indexed for MEDLINE]
5.

Protective effect of supplemental superoxide dismutase on survival of neuronal cells during starvation. Requirement for cytosolic distribution.

Matthews CC, Figueiredo DM, Wollack JB, Fairweather NF, Dougan G, Hallewell RA, Cadet JL, Fishman PS.

J Mol Neurosci. 2000 Jun;14(3):155-66.

PMID:
10984191
[PubMed - indexed for MEDLINE]
6.

Insect GDNF:TTC fusion protein improves delivery of GDNF to mouse CNS.

Li J, Chian RJ, Ay I, Kashi BB, Celia SA, Tamrazian E, Pepinsky RB, Fishman PS, Brown RH Jr, Francis JW.

Biochem Biophys Res Commun. 2009 Dec 18;390(3):947-51. doi: 10.1016/j.bbrc.2009.10.083. Epub 2009 Oct 21.

PMID:
19852934
[PubMed - indexed for MEDLINE]
7.

A survival motor neuron:tetanus toxin fragment C fusion protein for the targeted delivery of SMN protein to neurons.

Francis JW, Figueiredo D, vanderSpek JC, Ayala LM, Kim YS, Remington MP, Young PJ, Lorson CL, Ikebe S, Fishman PS, Brown RH Jr.

Brain Res. 2004 Jan 2;995(1):84-96.

PMID:
14644474
[PubMed - indexed for MEDLINE]
8.

CuZn superoxide dismutase (SOD-1):tetanus toxin fragment C hybrid protein for targeted delivery of SOD-1 to neuronal cells.

Francis JW, Hosler BA, Brown RH Jr, Fishman PS.

J Biol Chem. 1995 Jun 23;270(25):15434-42.

PMID:
7797532
[PubMed - indexed for MEDLINE]
Free Article
9.

[Expression, purification of tetanus toxin C fragment/cardiotrophin-1 recombinant fusion protein, target delivery to CNS and neurotrophy biology ability].

Chen C, Wang J, Yang P, Zhou Y, Zhang ZF.

Zhonghua Wai Ke Za Zhi. 2009 Feb 1;47(3):202-5. Chinese.

PMID:
19563075
[PubMed - indexed for MEDLINE]
10.

Effects of the PPARgamma activator pioglitazone on p38 MAP kinase and IkappaBalpha in the spinal cord of a transgenic mouse model of amyotrophic lateral sclerosis.

Shibata N, Kawaguchi-Niida M, Yamamoto T, Toi S, Hirano A, Kobayashi M.

Neuropathology. 2008 Aug;28(4):387-98. doi: 10.1111/j.1440-1789.2008.00890.x. Epub 2008 Feb 26.

PMID:
18312546
[PubMed - indexed for MEDLINE]
11.

C fragment of tetanus toxin hybrid proteins evaluated for muscle-specific transsynaptic mapping of spinal motor circuitry in the newborn mouse.

Perreault MC, Bernier AP, Renaud JS, Roux S, Glover JC.

Neuroscience. 2006 Aug 25;141(2):803-16. Epub 2006 May 18.

PMID:
16713105
[PubMed - indexed for MEDLINE]
12.

Recombinant GDNF: tetanus toxin fragment C fusion protein produced from insect cells.

Li J, Chian RJ, Ay I, Celia SA, Kashi BB, Tamrazian E, Matthews JC, Remington MP, Pepinsky RB, Fishman PS, Brown RH Jr, Francis JW.

Biochem Biophys Res Commun. 2009 Jul 31;385(3):380-4. doi: 10.1016/j.bbrc.2009.05.079. Epub 2009 May 22.

PMID:
19465006
[PubMed - indexed for MEDLINE]
13.

Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models.

Jonsson PA, Graffmo KS, Andersen PM, Brännström T, Lindberg M, Oliveberg M, Marklund SL.

Brain. 2006 Feb;129(Pt 2):451-64. Epub 2005 Dec 5.

PMID:
16330499
[PubMed - indexed for MEDLINE]
Free Article
14.

Immunization does not interfere with uptake and transport by motor neurons of the binding fragment of tetanus toxin.

Fishman PS, Matthews CC, Parks DA, Box M, Fairweather NF.

J Neurosci Res. 2006 Jun;83(8):1540-3.

PMID:
16557581
[PubMed - indexed for MEDLINE]
15.

Interaction of tetanus toxin derived hybrid proteins with neuronal cells.

Figueiredo DM, Matthews CC, Parks DA, Fairweather NF, Dougan G, Wilt SG, Fishman PS.

J Nat Toxins. 2000 Nov;9(4):363-79.

PMID:
11126515
[PubMed - indexed for MEDLINE]
16.

Brain-derived neurotrophic factor facilitates in vivo internalization of tetanus neurotoxin C-terminal fragment fusion proteins in mature mouse motor nerve terminals.

Roux S, Saint Cloment C, Curie T, Girard E, Mena FJ, Barbier J, Osta R, Molgó J, Brûlet P.

Eur J Neurosci. 2006 Sep;24(6):1546-54.

PMID:
17004918
[PubMed - indexed for MEDLINE]
17.

In vivo neuronal tracing with GFP-TTC gene delivery.

Kissa K, Mordelet E, Soudais C, Kremer EJ, Demeneix BA, Brûlet P, Coen L.

Mol Cell Neurosci. 2002 Aug;20(4):627-37.

PMID:
12213444
[PubMed - indexed for MEDLINE]
18.

Neuronal targeting of cardiotrophin-1 by coupling with tetanus toxin C fragment.

Bordet T, Castelnau-Ptakhine L, Fauchereau F, Friocourt G, Kahn A, Haase G.

Mol Cell Neurosci. 2001 May;17(5):842-54.

PMID:
11358482
[PubMed - indexed for MEDLINE]
19.

A genetic fusion GDNF-C fragment of tetanus toxin prolongs survival in a symptomatic mouse ALS model.

Ciriza J, Moreno-Igoa M, Calvo AC, Yague G, Palacio J, Miana-Mena FJ, Muñoz MJ, Zaragoza P, Brûlet P, Osta R.

Restor Neurol Neurosci. 2008;26(6):459-65.

PMID:
19096133
[PubMed - indexed for MEDLINE]
20.

Fragment C of tetanus toxin, more than a carrier. Novel perspectives in non-viral ALS gene therapy.

Moreno-Igoa M, Calvo AC, Penas C, Manzano R, Oliván S, Muñoz MJ, Mancuso R, Zaragoza P, Aguilera J, Navarro X, Osta Pinzolas R.

J Mol Med (Berl). 2010 Mar;88(3):297-308. doi: 10.1007/s00109-009-0556-y.

PMID:
19921501
[PubMed - indexed for MEDLINE]

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