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Results: 1 to 20 of 289

1.

Induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth: Otto Warburg revisited.

Schulz TJ, Thierbach R, Voigt A, Drewes G, Mietzner B, Steinberg P, Pfeiffer AF, Ristow M.

J Biol Chem. 2006 Jan 13;281(2):977-81. Epub 2005 Nov 1.

PMID:
16263703
[PubMed - indexed for MEDLINE]
Free Article
2.

Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice.

Thierbach R, Schulz TJ, Isken F, Voigt A, Mietzner B, Drewes G, von Kleist-Retzow JC, Wiesner RJ, Magnuson MA, Puccio H, Pfeiffer AF, Steinberg P, Ristow M.

Hum Mol Genet. 2005 Dec 15;14(24):3857-64. Epub 2005 Nov 8. Erratum in: Hum Mol Genet. 2007 Dec 1;16(23):2987.

PMID:
16278235
[PubMed - indexed for MEDLINE]
Free Article
3.

Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells.

Wu M, Neilson A, Swift AL, Moran R, Tamagnine J, Parslow D, Armistead S, Lemire K, Orrell J, Teich J, Chomicz S, Ferrick DA.

Am J Physiol Cell Physiol. 2007 Jan;292(1):C125-36. Epub 2006 Sep 13.

PMID:
16971499
[PubMed - indexed for MEDLINE]
Free Article
4.

Frataxin activates mitochondrial energy conversion and oxidative phosphorylation.

Ristow M, Pfister MF, Yee AJ, Schubert M, Michael L, Zhang CY, Ueki K, Michael MD 2nd, Lowell BB, Kahn CR.

Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12239-43.

PMID:
11035806
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Oxidative metabolism in cancer growth.

Ristow M.

Curr Opin Clin Nutr Metab Care. 2006 Jul;9(4):339-45. Review.

PMID:
16778561
[PubMed - indexed for MEDLINE]
6.

A pool of extramitochondrial frataxin that promotes cell survival.

Condò I, Ventura N, Malisan F, Tomassini B, Testi R.

J Biol Chem. 2006 Jun 16;281(24):16750-6. Epub 2006 Apr 11.

PMID:
16608849
[PubMed - indexed for MEDLINE]
Free Article
7.

Iron metabolism and mitochondrial abnormalities in Friedreich ataxia.

Pandolfo M.

Blood Cells Mol Dis. 2002 Nov-Dec;29(3):536-47; discussion 548-52. Review.

PMID:
12547248
[PubMed - indexed for MEDLINE]
8.

Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype.

de Groof AJ, te Lindert MM, van Dommelen MM, Wu M, Willemse M, Smift AL, Winer M, Oerlemans F, Pluk H, Fransen JA, Wieringa B.

Mol Cancer. 2009 Jul 31;8:54. doi: 10.1186/1476-4598-8-54.

PMID:
19646236
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin.

Oktay Y, Dioum E, Matsuzaki S, Ding K, Yan LJ, Haller RG, Szweda LI, Garcia JA.

J Biol Chem. 2007 Apr 20;282(16):11750-6. Epub 2007 Feb 23.

PMID:
17322295
[PubMed - indexed for MEDLINE]
Free Article
10.

Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect.

Chen Y, Cairns R, Papandreou I, Koong A, Denko NC.

PLoS One. 2009 Sep 15;4(9):e7033. doi: 10.1371/journal.pone.0007033.

PMID:
19753307
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Dual role of the mitochondrial protein frataxin in astrocytic tumors.

Kirches E, Andrae N, Hoefer A, Kehler B, Zarse K, Leverkus M, Keilhoff G, Schonfeld P, Schneider T, Wilisch-Neumann A, Mawrin C.

Lab Invest. 2011 Dec;91(12):1766-76. doi: 10.1038/labinvest.2011.130. Epub 2011 Aug 22.

PMID:
21863062
[PubMed - indexed for MEDLINE]
Free Article
12.

Causative role of oxidative stress in a Drosophila model of Friedreich ataxia.

Llorens JV, Navarro JA, Martínez-Sebastián MJ, Baylies MK, Schneuwly S, Botella JA, Moltó MD.

FASEB J. 2007 Feb;21(2):333-44. Epub 2006 Dec 13.

PMID:
17167074
[PubMed - indexed for MEDLINE]
Free Article
14.

Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension.

Chan SH, Wu CA, Wu KL, Ho YH, Chang AY, Chan JY.

Circ Res. 2009 Oct 23;105(9):886-96. doi: 10.1161/CIRCRESAHA.109.199018. Epub 2009 Sep 17.

PMID:
19762685
[PubMed - indexed for MEDLINE]
Free Article
15.

Mitochondria and cancer: Warburg addressed.

Wallace DC.

Cold Spring Harb Symp Quant Biol. 2005;70:363-74. Review.

PMID:
16869773
[PubMed - indexed for MEDLINE]
16.

Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones.

Shan Y, Napoli E, Cortopassi G.

Hum Mol Genet. 2007 Apr 15;16(8):929-41. Epub 2007 Mar 1.

PMID:
17331979
[PubMed - indexed for MEDLINE]
Free Article
17.

Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes.

Campuzano V, Montermini L, Lutz Y, Cova L, Hindelang C, Jiralerspong S, Trottier Y, Kish SJ, Faucheux B, Trouillas P, Authier FJ, Dürr A, Mandel JL, Vescovi A, Pandolfo M, Koenig M.

Hum Mol Genet. 1997 Oct;6(11):1771-80.

PMID:
9302253
[PubMed - indexed for MEDLINE]
Free Article
18.

Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity.

Bulteau AL, O'Neill HA, Kennedy MC, Ikeda-Saito M, Isaya G, Szweda LI.

Science. 2004 Jul 9;305(5681):242-5.

PMID:
15247478
[PubMed - indexed for MEDLINE]
Free Article
19.

Mitochondrial membrane cholesterol, the voltage dependent anion channel (VDAC), and the Warburg effect.

Campbell AM, Chan SH.

J Bioenerg Biomembr. 2008 Jun;40(3):193-7. doi: 10.1007/s10863-008-9138-x. Review.

PMID:
18677555
[PubMed - indexed for MEDLINE]
20.

Iron-dependent changes in cellular energy metabolism: influence on citric acid cycle and oxidative phosphorylation.

Oexle H, Gnaiger E, Weiss G.

Biochim Biophys Acta. 1999 Nov 10;1413(3):99-107.

PMID:
10556622
[PubMed - indexed for MEDLINE]
Free Article

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