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Results: 1 to 20 of 171

1.

Mutant KRAS in the initiation of pancreatic cancer.

Deramaudt T, Rustgi AK.

Biochim Biophys Acta. 2005 Nov 25;1756(2):97-101. Epub 2005 Sep 7. Review.

PMID:
16169155
[PubMed - indexed for MEDLINE]
2.
3.

Inactivation of Smad4 accelerates Kras(G12D)-mediated pancreatic neoplasia.

Kojima K, Vickers SM, Adsay NV, Jhala NC, Kim HG, Schoeb TR, Grizzle WE, Klug CA.

Cancer Res. 2007 Sep 1;67(17):8121-30.

PMID:
17804724
[PubMed - indexed for MEDLINE]
Free Article
4.

Relationship between K-ras mutation and the expression of p21WAF1/CIP1 and p53 in chronic pancreatitis and pancreatic adenocarcinoma.

Hermanová M, Lukás Z, Kroupová I, Kleibl Z, Novotný J, Nenutil R, Pazourková M, Brázdil J, Kren L, Díte P.

Neoplasma. 2003;50(5):319-25.

PMID:
14628083
[PubMed - indexed for MEDLINE]
5.

The mutant K-ras oncogene causes pancreatic periductal lymphocytic infiltration and gastric mucous neck cell hyperplasia in transgenic mice.

Brembeck FH, Schreiber FS, Deramaudt TB, Craig L, Rhoades B, Swain G, Grippo P, Stoffers DA, Silberg DG, Rustgi AK.

Cancer Res. 2003 May 1;63(9):2005-9.

PMID:
12727809
[PubMed - indexed for MEDLINE]
Free Article
6.

The K-ras mutation pattern in pancreatic ductal adenocarcinoma usually is identical to that in associated normal, hyperplastic, and metaplastic ductal epithelium.

Lüttges J, Schlehe B, Menke MA, Vogel I, Henne-Bruns D, Klöppel G.

Cancer. 1999 Apr 15;85(8):1703-10.

PMID:
10223563
[PubMed - indexed for MEDLINE]
7.
8.

Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.

Aguirre AJ, Bardeesy N, Sinha M, Lopez L, Tuveson DA, Horner J, Redston MS, DePinho RA.

Genes Dev. 2003 Dec 15;17(24):3112-26. Epub 2003 Dec 17.

PMID:
14681207
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Ductal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha-ras oncogene in rat pancreas.

Ueda S, Fukamachi K, Matsuoka Y, Takasuka N, Takeshita F, Naito A, Iigo M, Alexander DB, Moore MA, Saito I, Ochiya T, Tsuda H.

Carcinogenesis. 2006 Dec;27(12):2497-510. Epub 2006 Jun 13.

PMID:
16774944
[PubMed - indexed for MEDLINE]
Free Article
10.

Ductal neoplasia of the pancreas: nosologic, clinicopathologic, and biologic aspects.

Adsay NV, Basturk O, Cheng JD, Andea AA.

Semin Radiat Oncol. 2005 Oct;15(4):254-64. Review.

PMID:
16183479
[PubMed - indexed for MEDLINE]
11.

Lack of apoptosis in PanIN-1 and PanIN-2 lesions associated with pancreatic ductal adenocarcinoma is not dependent on K-ras status.

Lüttges J, Neumann S, Jesenofsky R, Borries V, Löhr M, Klöppel G.

Pancreas. 2003 Oct;27(3):e57-62. Erratum in: Pancreas. 2012 Mar;41(2):338. Jesnowski, Ralf [corrected to Jesenofsky, Ralf].

PMID:
14508142
[PubMed - indexed for MEDLINE]
12.

Pancreatic intraepithelial neoplasia in heterotopic pancreas: evidence for the progression model of pancreatic ductal adenocarcinoma.

Zhang L, Sanderson SO, Lloyd RV, Smyrk TC.

Am J Surg Pathol. 2007 Aug;31(8):1191-5.

PMID:
17667542
[PubMed - indexed for MEDLINE]
13.

Common occurrence of multiple K-RAS mutations in pancreatic cancers with associated precursor lesions and in biliary cancers.

Laghi L, Orbetegli O, Bianchi P, Zerbi A, Di Carlo V, Boland CR, Malesci A.

Oncogene. 2002 Jun 20;21(27):4301-6.

PMID:
12082617
[PubMed - indexed for MEDLINE]
Free Article
14.

The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models.

Shen R, Wang Q, Cheng S, Liu T, Jiang H, Zhu J, Wu Y, Wang L.

Cancer Lett. 2013 Oct 1;339(1):135-43. doi: 10.1016/j.canlet.2013.07.010. Epub 2013 Jul 22.

PMID:
23887057
[PubMed - indexed for MEDLINE]
Free Article
15.

Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas.

Izeradjene K, Combs C, Best M, Gopinathan A, Wagner A, Grady WM, Deng CX, Hruban RH, Adsay NV, Tuveson DA, Hingorani SR.

Cancer Cell. 2007 Mar;11(3):229-43.

PMID:
17349581
[PubMed - indexed for MEDLINE]
Free Article
16.

Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression.

Ijichi H, Chytil A, Gorska AE, Aakre ME, Fujitani Y, Fujitani S, Wright CV, Moses HL.

Genes Dev. 2006 Nov 15;20(22):3147-60.

PMID:
17114585
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors.

Seidler B, Schmidt A, Mayr U, Nakhai H, Schmid RM, Schneider G, Saur D.

Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10137-42. doi: 10.1073/pnas.0800487105. Epub 2008 Jul 11.

PMID:
18621715
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Early requirement of Rac1 in a mouse model of pancreatic cancer.

Heid I, Lubeseder-Martellato C, Sipos B, Mazur PK, Lesina M, Schmid RM, Siveke JT.

Gastroenterology. 2011 Aug;141(2):719-30, 730.e1-7. doi: 10.1053/j.gastro.2011.04.043. Epub 2011 Apr 28.

PMID:
21684285
[PubMed - indexed for MEDLINE]
19.

Ductal pancreatic cancer in humans and mice.

Tuveson DA, Hingorani SR.

Cold Spring Harb Symp Quant Biol. 2005;70:65-72. Review.

PMID:
16869739
[PubMed - indexed for MEDLINE]
20.

Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia.

Zhu L, Shi G, Schmidt CM, Hruban RH, Konieczny SF.

Am J Pathol. 2007 Jul;171(1):263-73.

PMID:
17591971
[PubMed - indexed for MEDLINE]
Free PMC Article

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