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Results: 1 to 20 of 453

1.

RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD.

Chi XZ, Yang JO, Lee KY, Ito K, Sakakura C, Li QL, Kim HR, Cha EJ, Lee YH, Kaneda A, Ushijima T, Kim WJ, Ito Y, Bae SC.

Mol Cell Biol. 2005 Sep;25(18):8097-107.

PMID:
16135801
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Smad pathway-specific transcriptional regulation of the cell cycle inhibitor p21(WAF1/Cip1).

Pardali K, Kowanetz M, Heldin CH, Moustakas A.

J Cell Physiol. 2005 Jul;204(1):260-72.

PMID:
15690394
[PubMed - indexed for MEDLINE]
3.

Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

Pardali K, Kurisaki A, Morén A, ten Dijke P, Kardassis D, Moustakas A.

J Biol Chem. 2000 Sep 22;275(38):29244-56.

PMID:
10878024
[PubMed - indexed for MEDLINE]
Free Article
4.

Growth regulation of gastric epithelial cells by Runx3.

Fukamachi H, Ito K.

Oncogene. 2004 May 24;23(24):4330-5. Review.

PMID:
15156189
[PubMed - indexed for MEDLINE]
5.

Tumor suppressor, AT motif binding factor 1 (ATBF1), translocates to the nucleus with runt domain transcription factor 3 (RUNX3) in response to TGF-beta signal transduction.

Mabuchi M, Kataoka H, Miura Y, Kim TS, Kawaguchi M, Ebi M, Tanaka M, Mori Y, Kubota E, Mizushima T, Shimura T, Mizoshita T, Tanida S, Kamiya T, Asai K, Joh T.

Biochem Biophys Res Commun. 2010 Jul 23;398(2):321-5. doi: 10.1016/j.bbrc.2010.06.090. Epub 2010 Jun 25.

PMID:
20599712
[PubMed - indexed for MEDLINE]
6.

Causal relationship between the loss of RUNX3 expression and gastric cancer.

Li QL, Ito K, Sakakura C, Fukamachi H, Inoue Ki, Chi XZ, Lee KY, Nomura S, Lee CW, Han SB, Kim HM, Kim WJ, Yamamoto H, Yamashita N, Yano T, Ikeda T, Itohara S, Inazawa J, Abe T, Hagiwara A, Yamagishi H, Ooe A, Kaneda A, Sugimura T, Ushijima T, Bae SC, Ito Y.

Cell. 2002 Apr 5;109(1):113-24.

PMID:
11955451
[PubMed - indexed for MEDLINE]
7.

Restoration of RUNX3 enhances transforming growth factor-beta-dependent p21 expression in a biliary tract cancer cell line.

Hasegawa K, Yazumi S, Wada M, Sakurai T, Kida M, Yamauchi J, Hisatsune H, Tada S, Ida H, Nakase Y, Sakakura C, Hagiwara A, Chiba T.

Cancer Sci. 2007 Jun;98(6):838-43.

PMID:
17470130
[PubMed - indexed for MEDLINE]
8.

Possible involvement of RUNX3 silencing in the peritoneal metastases of gastric cancers.

Sakakura C, Hasegawa K, Miyagawa K, Nakashima S, Yoshikawa T, Kin S, Nakase Y, Yazumi S, Yamagishi H, Okanoue T, Chiba T, Hagiwara A.

Clin Cancer Res. 2005 Sep 15;11(18):6479-88.

PMID:
16166423
[PubMed - indexed for MEDLINE]
Free Article
9.

Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.

Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ.

Clin Cancer Res. 2002 Nov;8(11):3628-38.

PMID:
12429655
[PubMed - indexed for MEDLINE]
Free Article
10.

RUNX3 inhibits cell proliferation and induces apoptosis by reinstating transforming growth factor beta responsiveness in esophageal adenocarcinoma cells.

Torquati A, O'rear L, Longobardi L, Spagnoli A, Richards WO, Daniel Beauchamp R.

Surgery. 2004 Aug;136(2):310-6.

PMID:
15300196
[PubMed - indexed for MEDLINE]
11.

Transforming growth factor beta 1 mediates cell-cycle arrest of primitive hematopoietic cells independent of p21(Cip1/Waf1) or p27(Kip1).

Cheng T, Shen H, Rodrigues N, Stier S, Scadden DT.

Blood. 2001 Dec 15;98(13):3643-9.

PMID:
11739168
[PubMed - indexed for MEDLINE]
Free Article
12.

The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis.

Yano T, Ito K, Fukamachi H, Chi XZ, Wee HJ, Inoue K, Ida H, Bouillet P, Strasser A, Bae SC, Ito Y.

Mol Cell Biol. 2006 Jun;26(12):4474-88.

PMID:
16738314
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Smad and p38-MAPK signaling mediates apoptotic effects of transforming growth factor-beta1 in human airway epithelial cells.

Undevia NS, Dorscheid DR, Marroquin BA, Gugliotta WL, Tse R, White SR.

Am J Physiol Lung Cell Mol Physiol. 2004 Sep;287(3):L515-24. Epub 2004 May 7.

PMID:
15132952
[PubMed - indexed for MEDLINE]
Free Article
14.

Beta-hydroxybutyrate-induced growth inhibition and collagen production in HK-2 cells are dependent on TGF-beta and Smad3.

Guh JY, Chuang TD, Chen HC, Hung WC, Lai YH, Shin SJ, Chuang LY.

Kidney Int. 2003 Dec;64(6):2041-51.

PMID:
14633126
[PubMed - indexed for MEDLINE]
15.

Smad expression in human atherosclerotic lesions: evidence for impaired TGF-beta/Smad signaling in smooth muscle cells of fibrofatty lesions.

Kalinina N, Agrotis A, Antropova Y, Ilyinskaya O, Smirnov V, Tararak E, Bobik A.

Arterioscler Thromb Vasc Biol. 2004 Aug;24(8):1391-6. Epub 2004 May 27.

PMID:
15166010
[PubMed - indexed for MEDLINE]
Free Article
16.

TGF-beta1 acts as a tumor suppressor of human malignant keratinocytes independently of Smad 4 expression and ligand-induced G(1) arrest.

Paterson IC, Davies M, Stone A, Huntley S, Smith E, Pring M, Eveson JW, Robinson CM, Parkinson EK, Prime SS.

Oncogene. 2002 Feb 28;21(10):1616-24.

PMID:
11896591
[PubMed - indexed for MEDLINE]
Free Article
17.

Smad4-independent regulation of p21/WAF1 by transforming growth factor-beta.

Ijichi H, Otsuka M, Tateishi K, Ikenoue T, Kawakami T, Kanai F, Arakawa Y, Seki N, Shimizu K, Miyazono K, Kawabe T, Omata M.

Oncogene. 2004 Feb 5;23(5):1043-51.

PMID:
14762439
[PubMed - indexed for MEDLINE]
18.

Runx3 controls growth and differentiation of gastric epithelial cells in mammals.

Fukamachi H.

Dev Growth Differ. 2006 Jan;48(1):1-13. Review.

PMID:
16466388
[PubMed - indexed for MEDLINE]
19.
20.

GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling.

Saeki N, Kim DH, Usui T, Aoyagi K, Tatsuta T, Aoki K, Yanagihara K, Tamura M, Mizushima H, Sakamoto H, Ogawa K, Ohki M, Shiroishi T, Yoshida T, Sasaki H.

Oncogene. 2007 Oct 4;26(45):6488-98. Epub 2007 Apr 30.

PMID:
17471240
[PubMed - indexed for MEDLINE]

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