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Results: 1 to 20 of 169

1.

The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity.

Coppari R, Ichinose M, Lee CE, Pullen AE, Kenny CD, McGovern RA, Tang V, Liu SM, Ludwig T, Chua SC Jr, Lowell BB, Elmquist JK.

Cell Metab. 2005 Jan;1(1):63-72.

PMID:
16054045
[PubMed - indexed for MEDLINE]
Free Article
2.

Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes.

de Luca C, Kowalski TJ, Zhang Y, Elmquist JK, Lee C, Kilimann MW, Ludwig T, Liu SM, Chua SC Jr.

J Clin Invest. 2005 Dec;115(12):3484-93. Epub 2005 Nov 10.

PMID:
16284652
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis.

Balthasar N, Coppari R, McMinn J, Liu SM, Lee CE, Tang V, Kenny CD, McGovern RA, Chua SC Jr, Elmquist JK, Lowell BB.

Neuron. 2004 Jun 24;42(6):983-91.

PMID:
15207242
[PubMed - indexed for MEDLINE]
4.

Transgenic complementation of leptin-receptor deficiency. I. Rescue of the obesity/diabetes phenotype of LEPR-null mice expressing a LEPR-B transgene.

Kowalski TJ, Liu SM, Leibel RL, Chua SC Jr.

Diabetes. 2001 Feb;50(2):425-35.

PMID:
11272157
[PubMed - indexed for MEDLINE]
Free Article
5.

Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis.

Dhillon H, Zigman JM, Ye C, Lee CE, McGovern RA, Tang V, Kenny CD, Christiansen LM, White RD, Edelstein EA, Coppari R, Balthasar N, Cowley MA, Chua S Jr, Elmquist JK, Lowell BB.

Neuron. 2006 Jan 19;49(2):191-203.

PMID:
16423694
[PubMed - indexed for MEDLINE]
Free Article
6.

The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.

Covey SD, Wideman RD, McDonald C, Unniappan S, Huynh F, Asadi A, Speck M, Webber T, Chua SC, Kieffer TJ.

Cell Metab. 2006 Oct;4(4):291-302.

PMID:
17011502
[PubMed - indexed for MEDLINE]
Free Article
7.

Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice.

Berglund ED, Vianna CR, Donato J Jr, Kim MH, Chuang JC, Lee CE, Lauzon DA, Lin P, Brule LJ, Scott MM, Coppari R, Elmquist JK.

J Clin Invest. 2012 Mar;122(3):1000-9. doi: 10.1172/JCI59816. Epub 2012 Feb 13.

PMID:
22326958
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

STAT3 signalling is required for leptin regulation of energy balance but not reproduction.

Bates SH, Stearns WH, Dundon TA, Schubert M, Tso AW, Wang Y, Banks AS, Lavery HJ, Haq AK, Maratos-Flier E, Neel BG, Schwartz MW, Myers MG Jr.

Nature. 2003 Feb 20;421(6925):856-9.

PMID:
12594516
[PubMed - indexed for MEDLINE]
9.

Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis.

Elmquist JK, Coppari R, Balthasar N, Ichinose M, Lowell BB.

J Comp Neurol. 2005 Dec 5;493(1):63-71. Review.

PMID:
16254991
[PubMed - indexed for MEDLINE]
10.

An allelic series for the leptin receptor gene generated by CRE and FLP recombinase.

McMinn JE, Liu SM, Dragatsis I, Dietrich P, Ludwig T, Eiden S, Chua SC Jr.

Mamm Genome. 2004 Sep;15(9):677-85.

PMID:
15389315
[PubMed - indexed for MEDLINE]
11.

Activation of the hypothalamic arcuate nucleus predicts the anorectic actions of ciliary neurotrophic factor and leptin in intact and gold thioglucose-lesioned mice.

Anderson KD, Lambert PD, Corcoran TL, Murray JD, Thabet KE, Yancopoulos GD, Wiegand SJ.

J Neuroendocrinol. 2003 Jul;15(7):649-60.

PMID:
12787049
[PubMed - indexed for MEDLINE]
12.

Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons.

Donato J Jr, Cravo RM, Fraz√£o R, Gautron L, Scott MM, Lachey J, Castro IA, Margatho LO, Lee S, Lee C, Richardson JA, Friedman J, Chua S Jr, Coppari R, Zigman JM, Elmquist JK, Elias CF.

J Clin Invest. 2011 Jan;121(1):355-68. doi: 10.1172/JCI45106. Epub 2010 Dec 22.

PMID:
21183787
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Genetic dissection of neuronal pathways controlling energy homeostasis.

Balthasar N.

Obesity (Silver Spring). 2006 Aug;14 Suppl 5:222S-227S. Review.

PMID:
17021371
[PubMed - indexed for MEDLINE]
14.

Neuronal deletion of Lepr elicits diabesity in mice without affecting cold tolerance or fertility.

McMinn JE, Liu SM, Liu H, Dragatsis I, Dietrich P, Ludwig T, Boozer CN, Chua SC Jr.

Am J Physiol Endocrinol Metab. 2005 Sep;289(3):E403-11. Epub 2005 May 3.

PMID:
15870101
[PubMed - indexed for MEDLINE]
Free Article
15.

Mice lacking ghrelin receptors resist the development of diet-induced obesity.

Zigman JM, Nakano Y, Coppari R, Balthasar N, Marcus JN, Lee CE, Jones JE, Deysher AE, Waxman AR, White RD, Williams TD, Lachey JL, Seeley RJ, Lowell BB, Elmquist JK.

J Clin Invest. 2005 Dec;115(12):3564-72.

PMID:
16322794
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Transgenic complementation of leptin receptor deficiency. II. Increased leptin receptor transgene dose effects on obesity/diabetes and fertility/lactation in lepr-db/db mice.

Chua SC Jr, Liu SM, Li Q, Sun A, DeNino WF, Heymsfield SB, Guo XE.

Am J Physiol Endocrinol Metab. 2004 Mar;286(3):E384-92. Epub 2003 Nov 4.

PMID:
14600075
[PubMed - indexed for MEDLINE]
Free Article
17.

Trophic action of leptin on hypothalamic neurons that regulate feeding.

Bouret SG, Draper SJ, Simerly RB.

Science. 2004 Apr 2;304(5667):108-10.

PMID:
15064420
[PubMed - indexed for MEDLINE]
Free Article
18.

Electrophysiological actions of peripheral hormones on melanocortin neurons.

Cowley MA, Cone R, Enriori P, Louiselle I, Williams SM, Evans AE.

Ann N Y Acad Sci. 2003 Jun;994:175-86. Review.

PMID:
12851314
[PubMed - indexed for MEDLINE]
19.

Stereological analysis of estrogen receptor expression in the hypothalamic arcuate nucleus of ob/ob and agouti mice.

Chakraborty S, Sachdev A, Salton SR, Chakraborty TR.

Brain Res. 2008 Jun 27;1217:86-95. doi: 10.1016/j.brainres.2008.04.031. Epub 2008 Apr 23.

PMID:
18502406
[PubMed - indexed for MEDLINE]
20.

Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons.

Morton GJ, Gelling RW, Niswender KD, Morrison CD, Rhodes CJ, Schwartz MW.

Cell Metab. 2005 Dec;2(6):411-20.

PMID:
16330326
[PubMed - indexed for MEDLINE]
Free Article
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