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Results: 1 to 20 of 90

1.

Structure and chemistry of cytochrome P450.

Denisov IG, Makris TM, Sligar SG, Schlichting I.

Chem Rev. 2005 Jun;105(6):2253-77. Review. No abstract available.

PMID:
15941214
[PubMed - indexed for MEDLINE]
2.

Theoretical perspective on the structure and mechanism of cytochrome P450 enzymes.

Shaik S, Kumar D, de Visser SP, Altun A, Thiel W.

Chem Rev. 2005 Jun;105(6):2279-328. Review. No abstract available.

PMID:
15941215
[PubMed - indexed for MEDLINE]
3.

Cytochrome P450.

Poulos TL.

Curr Opin Struct Biol. 1995 Dec;5(6):767-74. Review.

PMID:
8749364
[PubMed - indexed for MEDLINE]
4.

Cytochrome p450 in silico: an integrative modeling approach.

de Graaf C, Vermeulen NP, Feenstra KA.

J Med Chem. 2005 Apr 21;48(8):2725-55. Review. No abstract available.

PMID:
15828810
[PubMed - indexed for MEDLINE]
5.

Engineered alkane-hydroxylating cytochrome P450(BM3) exhibiting nativelike catalytic properties.

Fasan R, Chen MM, Crook NC, Arnold FH.

Angew Chem Int Ed Engl. 2007;46(44):8414-8. No abstract available.

PMID:
17886313
[PubMed - indexed for MEDLINE]
6.

Intermediates in P450 catalysis.

Poulos TL.

Philos Trans A Math Phys Eng Sci. 2005 Apr 15;363(1829):793-806; discussion 1035-40. Review.

PMID:
15901536
[PubMed - indexed for MEDLINE]
7.

Cytochrome p450 conformational diversity.

Stout CD.

Structure. 2004 Nov;12(11):1921-2.

PMID:
15530355
[PubMed - indexed for MEDLINE]
8.

Structural models for cytochrome P450-mediated catalysis.

Lewis DF.

ScientificWorldJournal. 2003 Jun 20;3:536-45. Review.

PMID:
12847303
[PubMed - indexed for MEDLINE]
Free Article
9.

Molecular replacement in P450 crystal structure determinations.

Li H, Yano JK, Poulos TL.

Methods Enzymol. 2002;357:79-93. No abstract available.

PMID:
12424900
[PubMed - indexed for MEDLINE]
10.

Flavocytochrome P450 BM3 and the origin of CYP102 fusion species.

Girvan HM, Waltham TN, Neeli R, Collins HF, McLean KJ, Scrutton NS, Leys D, Munro AW.

Biochem Soc Trans. 2006 Dec;34(Pt 6):1173-7. Review.

PMID:
17073779
[PubMed - indexed for MEDLINE]
11.

Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3.

Girvan HM, Seward HE, Toogood HS, Cheesman MR, Leys D, Munro AW.

J Biol Chem. 2007 Jan 5;282(1):564-72. Epub 2006 Oct 31.

PMID:
17077084
[PubMed - indexed for MEDLINE]
Free Article
12.

About oxygen, cytochrome p450 and titanium: learning from Ron Estabrook.

Jung C.

Drug Metab Rev. 2007;39(2-3):501-13. Review.

PMID:
17786635
[PubMed - indexed for MEDLINE]
13.

A thiolate-ligated nonheme oxoiron(IV) complex relevant to cytochrome P450.

Bukowski MR, Koehntop KD, Stubna A, Bominaar EL, Halfen JA, M√ľnck E, Nam W, Que L Jr.

Science. 2005 Nov 11;310(5750):1000-2. Epub 2005 Oct 27.

PMID:
16254150
[PubMed - indexed for MEDLINE]
Free Article
14.

Binding of CYP2C9 with diverse drugs and its implications for metabolic mechanism.

Wang JF, Yan JY, Wei DQ, Chou KC.

Med Chem. 2009 May;5(3):263-70.

PMID:
19442216
[PubMed - indexed for MEDLINE]
15.

Hydrogen peroxide dependent monooxygenations by tricking the substrate recognition of cytochrome P450BSbeta.

Shoji O, Fujishiro T, Nakajima H, Kim M, Nagano S, Shiro Y, Watanabe Y.

Angew Chem Int Ed Engl. 2007;46(20):3656-9. No abstract available.

PMID:
17385817
[PubMed - indexed for MEDLINE]
16.

Structural biology of p450-oxy complexes.

Poulos TL.

Drug Metab Rev. 2007;39(2-3):557-66. Review. No abstract available.

PMID:
17786638
[PubMed - indexed for MEDLINE]
17.

Electronic structure of compound I in human isoforms of cytochrome P450 from QM/MM modeling.

Bathelt CM, Zurek J, Mulholland AJ, Harvey JN.

J Am Chem Soc. 2005 Sep 21;127(37):12900-8.

PMID:
16159284
[PubMed - indexed for MEDLINE]
18.

Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity.

Lewis DF, Ito Y.

Xenobiotica. 2009 Aug;39(8):625-35. doi: 10.1080/00498250903000255. Review.

PMID:
19514836
[PubMed - indexed for MEDLINE]
19.

[Physiological function, reaction mechanism, and structure of cytochrone P450nor].

Shoun H, Fushinobu S.

Seikagaku. 2008 Jun;80(6):560-8. Review. Japanese. No abstract available.

PMID:
18634431
[PubMed - indexed for MEDLINE]
20.

Alkane hydroxylation by peroxy acids: a comparison with the cytochrome P450 hydroxylation.

Groenhof AR, Ehlers AW, Lammertsma K.

J Phys Chem A. 2008 Dec 18;112(50):12855-61. doi: 10.1021/jp801720s.

PMID:
18956858
[PubMed - indexed for MEDLINE]

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