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Related Citations for PubMed (Select 15933056)


Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells.

Calmels B, Ferguson C, Laukkanen MO, Adler R, Faulhaber M, Kim HJ, Sellers S, Hematti P, Schmidt M, von Kalle C, Akagi K, Donahue RE, Dunbar CE.

Blood. 2005 Oct 1;106(7):2530-3. Epub 2005 Jun 2.


The MDS1-EVI1 gene complex as a retrovirus integration site: impact on behavior of hematopoietic cells and implications for gene therapy.

Métais JY, Dunbar CE.

Mol Ther. 2008 Mar;16(3):439-49. doi: 10.1038/ Epub 2008 Jan 29. Review.


Ex vivo expansion of retrovirally transduced primate CD34+ cells results in overrepresentation of clones with MDS1/EVI1 insertion sites in the myeloid lineage after transplantation.

Sellers S, Gomes TJ, Larochelle A, Lopez R, Adler R, Krouse A, Donahue RE, Childs RW, Dunbar CE.

Mol Ther. 2010 Sep;18(9):1633-9. doi: 10.1038/mt.2010.117. Epub 2010 Jun 22.


Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34+ cells.

Kim YJ, Kim YS, Larochelle A, Renaud G, Wolfsberg TG, Adler R, Donahue RE, Hematti P, Hong BK, Roayaei J, Akagi K, Riberdy JM, Nienhuis AW, Dunbar CE, Persons DA.

Blood. 2009 May 28;113(22):5434-43. doi: 10.1182/blood-2008-10-185199. Epub 2009 Apr 1.


Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia.

Kiem HP, Sellers S, Thomasson B, Morris JC, Tisdale JF, Horn PA, Hematti P, Adler R, Kuramoto K, Calmels B, Bonifacino A, Hu J, von Kalle C, Schmidt M, Sorrentino B, Nienhuis A, Blau CA, Andrews RG, Donahue RE, Dunbar CE.

Mol Ther. 2004 Mar;9(3):389-95.


Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking.

Kustikova O, Fehse B, Modlich U, Yang M, Düllmann J, Kamino K, von Neuhoff N, Schlegelberger B, Li Z, Baum C.

Science. 2005 May 20;308(5725):1171-4.


Repetitive busulfan administration after hematopoietic stem cell gene therapy associated with a dominant HDAC7 clone in a nonhuman primate.

Xie J, Larochelle A, Maric I, Faulhaber M, Donahue RE, Dunbar CE.

Hum Gene Ther. 2010 Jun;21(6):695-703. doi: 10.1089/hum.2009.191.


Leukemia induction after a single retroviral vector insertion in Evi1 or Prdm16.

Modlich U, Schambach A, Brugman MH, Wicke DC, Knoess S, Li Z, Maetzig T, Rudolph C, Schlegelberger B, Baum C.

Leukemia. 2008 Aug;22(8):1519-28. doi: 10.1038/leu.2008.118. Epub 2008 May 22.


Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy.

Aiuti A, Cassani B, Andolfi G, Mirolo M, Biasco L, Recchia A, Urbinati F, Valacca C, Scaramuzza S, Aker M, Slavin S, Cazzola M, Sartori D, Ambrosi A, Di Serio C, Roncarolo MG, Mavilio F, Bordignon C.

J Clin Invest. 2007 Aug;117(8):2233-40.


Significant increase of self-renewal in hematopoietic cells after forced expression of EVI1.

Laricchia-Robbio L, Nucifora G.

Blood Cells Mol Dis. 2008 Mar-Apr;40(2):141-7. Epub 2007 Oct 29.


Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells.

Hematti P, Hong BK, Ferguson C, Adler R, Hanawa H, Sellers S, Holt IE, Eckfeldt CE, Sharma Y, Schmidt M, von Kalle C, Persons DA, Billings EM, Verfaillie CM, Nienhuis AW, Wolfsberg TG, Dunbar CE, Calmels B.

PLoS Biol. 2004 Dec;2(12):e423. Epub 2004 Nov 23.


Marking and gene expression by a lentivirus vector in transplanted human and nonhuman primate CD34(+) cells.

An DS, Wersto RP, Agricola BA, Metzger ME, Lu S, Amado RG, Chen IS, Donahue RE.

J Virol. 2000 Feb;74(3):1286-95.


Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells.

Beard BC, Dickerson D, Beebe K, Gooch C, Fletcher J, Okbinoglu T, Miller DG, Jacobs MA, Kaul R, Kiem HP, Trobridge GD.

Mol Ther. 2007 Jul;15(7):1356-65. Epub 2007 Apr 17.


Transient in vivo beta-globin production after lentiviral gene transfer to hematopoietic stem cells in the nonhuman primate.

Hayakawa J, Ueda T, Lisowski L, Hsieh MM, Washington K, Phang O, Metzger M, Krouse A, Donahue RE, Sadelain M, Tisdale JF.

Hum Gene Ther. 2009 Jun;20(6):563-72. doi: 10.1089/hum.2008.186.


Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

Ott MG, Schmidt M, Schwarzwaelder K, Stein S, Siler U, Koehl U, Glimm H, Kühlcke K, Schilz A, Kunkel H, Naundorf S, Brinkmann A, Deichmann A, Fischer M, Ball C, Pilz I, Dunbar C, Du Y, Jenkins NA, Copeland NG, Lüthi U, Hassan M, Thrasher AJ, Hoelzer D, von Kalle C, Seger R, Grez M.

Nat Med. 2006 Apr;12(4):401-9. Epub 2006 Apr 2.


Self-inactivating retroviral vector-mediated gene transfer induces oncogene activation and immortalization of primary murine bone marrow cells.

Bosticardo M, Ghosh A, Du Y, Jenkins NA, Copeland NG, Candotti F.

Mol Ther. 2009 Nov;17(11):1910-8. doi: 10.1038/mt.2009.172. Epub 2009 Jul 28.


The role of EVI1 in normal and leukemic cells.

Buonamici S, Chakraborty S, Senyuk V, Nucifora G.

Blood Cells Mol Dis. 2003 Sep-Oct;31(2):206-12. Review.


EVI1 and MDS1/EVI1 expression during primary human hematopoietic progenitor cell differentiation into various myeloid lineages.

Steinleitner K, Rampetsreiter P, Köffel R, Ramanathan G, Mannhalter C, Strobl H, Wieser R.

Anticancer Res. 2012 Nov;32(11):4883-9.

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