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Results: 1 to 20 of 258

1.

HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor.

Kovacs JJ, Murphy PJ, Gaillard S, Zhao X, Wu JT, Nicchitta CV, Yoshida M, Toft DO, Pratt WB, Yao TP.

Mol Cell. 2005 May 27;18(5):601-7.

PMID:
15916966
[PubMed - indexed for MEDLINE]
Free Article
2.

Modulating molecular chaperone Hsp90 functions through reversible acetylation.

Aoyagi S, Archer TK.

Trends Cell Biol. 2005 Nov;15(11):565-7. Epub 2005 Sep 30.

PMID:
16199163
[PubMed - indexed for MEDLINE]
3.

Regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone.

Murphy PJ, Morishima Y, Kovacs JJ, Yao TP, Pratt WB.

J Biol Chem. 2005 Oct 7;280(40):33792-9. Epub 2005 Aug 8.

PMID:
16087666
[PubMed - indexed for MEDLINE]
Free Article
4.

HDAC6 inhibition enhances 17-AAG--mediated abrogation of hsp90 chaperone function in human leukemia cells.

Rao R, Fiskus W, Yang Y, Lee P, Joshi R, Fernandez P, Mandawat A, Atadja P, Bradner JE, Bhalla K.

Blood. 2008 Sep 1;112(5):1886-93. doi: 10.1182/blood-2008-03-143644. Epub 2008 Jun 30.

PMID:
18591380
[PubMed - indexed for MEDLINE]
Free Article
5.

Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.

Bali P, Pranpat M, Bradner J, Balasis M, Fiskus W, Guo F, Rocha K, Kumaraswamy S, Boyapalle S, Atadja P, Seto E, Bhalla K.

J Biol Chem. 2005 Jul 22;280(29):26729-34. Epub 2005 Jun 2.

PMID:
15937340
[PubMed - indexed for MEDLINE]
Free Article
6.

HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling.

Kekatpure VD, Dannenberg AJ, Subbaramaiah K.

J Biol Chem. 2009 Mar 20;284(12):7436-45. doi: 10.1074/jbc.M808999200. Epub 2009 Jan 21.

PMID:
19158084
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

HDAC6 regulates glucocorticoid receptor signaling in serotonin pathways with critical impact on stress resilience.

Espallergues J, Teegarden SL, Veerakumar A, Boulden J, Challis C, Jochems J, Chan M, Petersen T, Deneris E, Matthias P, Hahn CG, Lucki I, Beck SG, Berton O.

J Neurosci. 2012 Mar 28;32(13):4400-16. doi: 10.1523/JNEUROSCI.5634-11.2012.

PMID:
22457490
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function.

Basak S, Pookot D, Noonan EJ, Dahiya R.

Mol Cancer Ther. 2008 Oct;7(10):3195-202. doi: 10.1158/1535-7163.MCT-08-0617.

PMID:
18852123
[PubMed - indexed for MEDLINE]
Free Article
9.

The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex.

Dittmar KD, Banach M, Galigniana MD, Pratt WB.

J Biol Chem. 1998 Mar 27;273(13):7358-66.

PMID:
9516432
[PubMed - indexed for MEDLINE]
Free Article
10.

A conserved proline in the hsp90 binding region of the glucocorticoid receptor is required for hsp90 heterocomplex stabilization and receptor signaling.

CaamaƱo CA, Morano MI, Dalman FC, Pratt WB, Akil H.

J Biol Chem. 1998 Aug 7;273(32):20473-80.

PMID:
9685402
[PubMed - indexed for MEDLINE]
Free Article
11.

Differential effects of the hsp70-binding protein BAG-1 on glucocorticoid receptor folding by the hsp90-based chaperone machinery.

Kanelakis KC, Morishima Y, Dittmar KD, Galigniana MD, Takayama S, Reed JC, Pratt WB.

J Biol Chem. 1999 Nov 26;274(48):34134-40.

PMID:
10567384
[PubMed - indexed for MEDLINE]
Free Article
12.

Ability of various members of the hsp70 family of chaperones to promote assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90.

Hutchison KA, Dittmar KD, Stancato LF, Pratt WB.

J Steroid Biochem Mol Biol. 1996 Jun;58(3):251-8.

PMID:
8836160
[PubMed - indexed for MEDLINE]
14.

Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6.

Gibbs A, Schwartzman J, Deng V, Alumkal J.

Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16663-8. doi: 10.1073/pnas.0908908106. Epub 2009 Sep 15.

PMID:
19805354
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

hsp70 interacting protein Hip does not affect glucocorticoid receptor folding by the hsp90-based chaperone machinery except to oppose the effect of BAG-1.

Kanelakis KC, Murphy PJ, Galigniana MD, Morishima Y, Takayama S, Reed JC, Toft DO, Pratt WB.

Biochemistry. 2000 Nov 21;39(46):14314-21.

PMID:
11087380
[PubMed - indexed for MEDLINE]
16.

The hsp90 cochaperone p23 is the limiting component of the multiprotein hsp90/hsp70-based chaperone system in vivo where it acts to stabilize the client protein: hsp90 complex.

Morishima Y, Kanelakis KC, Murphy PJ, Lowe ER, Jenkins GJ, Osawa Y, Sunahara RK, Pratt WB.

J Biol Chem. 2003 Dec 5;278(49):48754-63. Epub 2003 Sep 24.

PMID:
14507910
[PubMed - indexed for MEDLINE]
Free Article
17.
18.

Chaperoning steroid hormone signaling via reversible acetylation.

Kovacs JJ, Cohen TJ, Yao TP.

Nucl Recept Signal. 2005;3:e004. Epub 2005 Oct 21.

PMID:
16604172
[PubMed]
Free PMC Article
19.

Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation.

Murphy PJ, Galigniana MD, Morishima Y, Harrell JM, Kwok RP, Ljungman M, Pratt WB.

J Biol Chem. 2004 Jul 16;279(29):30195-201. Epub 2004 May 15.

PMID:
15145929
[PubMed - indexed for MEDLINE]
Free Article
20.

Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis.

Gao YS, Hubbert CC, Lu J, Lee YS, Lee JY, Yao TP.

Mol Cell Biol. 2007 Dec;27(24):8637-47. Epub 2007 Oct 15.

PMID:
17938201
[PubMed - indexed for MEDLINE]
Free PMC Article

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