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Results: 1 to 20 of 117

1.

Mechanistic perspectives for 1,2,4-trioxanes in anti-cancer therapy.

Efferth T.

Drug Resist Updat. 2005 Feb-Apr;8(1-2):85-97. Review.

PMID:
15878303
[PubMed - indexed for MEDLINE]
2.

Willmar Schwabe Award 2006: antiplasmodial and antitumor activity of artemisinin--from bench to bedside.

Efferth T.

Planta Med. 2007 Apr;73(4):299-309. Epub 2007 Mar 12. Review.

PMID:
17354163
[PubMed - indexed for MEDLINE]
3.

Molecular modes of action of artesunate in tumor cell lines.

Efferth T, Sauerbrey A, Olbrich A, Gebhart E, Rauch P, Weber HO, Hengstler JG, Halatsch ME, Volm M, Tew KD, Ross DD, Funk JO.

Mol Pharmacol. 2003 Aug;64(2):382-94.

PMID:
12869643
[PubMed - indexed for MEDLINE]
Free Article
4.

Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells.

Efferth T.

Curr Drug Targets. 2006 Apr;7(4):407-21. Review.

PMID:
16611029
[PubMed - indexed for MEDLINE]
5.

mRNA expression profiles for the response of human tumor cell lines to the antimalarial drugs artesunate, arteether, and artemether.

Efferth T, Olbrich A, Bauer R.

Biochem Pharmacol. 2002 Aug 15;64(4):617-23.

PMID:
12167480
[PubMed - indexed for MEDLINE]
6.

Factors determining sensitivity or resistance of tumor cell lines towards artesunate.

Sertel S, Eichhorn T, Sieber S, Sauer A, Weiss J, Plinkert PK, Efferth T.

Chem Biol Interact. 2010 Apr 15;185(1):42-52. doi: 10.1016/j.cbi.2010.02.002. Epub 2010 Feb 6.

PMID:
20144594
[PubMed - indexed for MEDLINE]
7.

The anti-malarial artesunate is also active against cancer.

Efferth T, Dunstan H, Sauerbrey A, Miyachi H, Chitambar CR.

Int J Oncol. 2001 Apr;18(4):767-73.

PMID:
11251172
[PubMed - indexed for MEDLINE]
8.

Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid.

Ro DK, Ouellet M, Paradise EM, Burd H, Eng D, Paddon CJ, Newman JD, Keasling JD.

BMC Biotechnol. 2008 Nov 4;8:83. doi: 10.1186/1472-6750-8-83.

PMID:
18983675
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Oxidative stress response of tumor cells: microarray-based comparison between artemisinins and anthracyclines.

Efferth T, Oesch F.

Biochem Pharmacol. 2004 Jul 1;68(1):3-10.

PMID:
15183112
[PubMed - indexed for MEDLINE]
10.

Glutathione-related enzymes contribute to resistance of tumor cells and low toxicity in normal organs to artesunate.

Efferth T, Volm M.

In Vivo. 2005 Jan-Feb;19(1):225-32.

PMID:
15796179
[PubMed - indexed for MEDLINE]
Free Article
11.

Pharmacogenomic identification of c-Myc/Max-regulated genes associated with cytotoxicity of artesunate towards human colon, ovarian and lung cancer cell lines.

Sertel S, Eichhorn T, Simon CH, Plinkert PK, Johnson SW, Efferth T.

Molecules. 2010 Apr 22;15(4):2886-910. doi: 10.3390/molecules15042886.

PMID:
20428086
[PubMed - indexed for MEDLINE]
Free Article
12.

Combination treatment of malignant B cells using the anti-CD20 antibody rituximab and the anti-malarial artesunate.

Sieber S, Gdynia G, Roth W, Bonavida B, Efferth T.

Int J Oncol. 2009 Jul;35(1):149-58.

PMID:
19513562
[PubMed - indexed for MEDLINE]
13.

Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines.

Michaelis M, Kleinschmidt MC, Barth S, Rothweiler F, Geiler J, Breitling R, Mayer B, Deubzer H, Witt O, Kreuter J, Doerr HW, Cinatl J, Cinatl J Jr.

Biochem Pharmacol. 2010 Jan 15;79(2):130-6. doi: 10.1016/j.bcp.2009.08.013. Epub 2009 Aug 19.

PMID:
19698702
[PubMed - indexed for MEDLINE]
14.

Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins.

Anfosso L, Efferth T, Albini A, Pfeffer U.

Pharmacogenomics J. 2006 Jul-Aug;6(4):269-78. Epub 2006 Jan 24.

PMID:
16432535
[PubMed - indexed for MEDLINE]
15.

Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate.

Dell'Eva R, Pfeffer U, Vené R, Anfosso L, Forlani A, Albini A, Efferth T.

Biochem Pharmacol. 2004 Dec 15;68(12):2359-66.

PMID:
15548382
[PubMed - indexed for MEDLINE]
16.

Molecular modes of action of cephalotaxine and homoharringtonine from the coniferous tree Cephalotaxus hainanensis in human tumor cell lines.

Efferth T, Sauerbrey A, Halatsch ME, Ross DD, Gebhart E.

Naunyn Schmiedebergs Arch Pharmacol. 2003 Jan;367(1):56-67. Epub 2002 Nov 5.

PMID:
12616342
[PubMed - indexed for MEDLINE]
17.

The Plasmodium falciparum translationally controlled tumor protein homolog and its reaction with the antimalarial drug artemisinin.

Bhisutthibhan J, Pan XQ, Hossler PA, Walker DJ, Yowell CA, Carlton J, Dame JB, Meshnick SR.

J Biol Chem. 1998 Jun 26;273(26):16192-8.

PMID:
9632675
[PubMed - indexed for MEDLINE]
Free Article
18.

[Review of the use of artemisinin and its derivatives in the treatment of malaria].

Van der Meersch H.

J Pharm Belg. 2005;60(1):23-9. Review. French. Erratum in: J Pharm Belg. 2005;60(3):103.

PMID:
15828489
[PubMed - indexed for MEDLINE]
19.
20.

Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo.

Vivas L, Rattray L, Stewart L, Bongard E, Robinson BL, Peters W, Croft SL.

Acta Trop. 2008 Mar;105(3):222-8. doi: 10.1016/j.actatropica.2007.12.005. Epub 2007 Dec 23.

PMID:
18279817
[PubMed - indexed for MEDLINE]

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