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Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding.

Das B, Shu X, Day GJ, Han J, Krishna UM, Falck JR, Broek D.

J Biol Chem. 2000 May 19;275(20):15074-81.


The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity.

Baran CP, Tridandapani S, Helgason CD, Humphries RK, Krystal G, Marsh CB.

J Biol Chem. 2003 Oct 3;278(40):38628-36. Epub 2003 Jul 25.


SHIP2 is recruited to the cell membrane upon macrophage colony-stimulating factor (M-CSF) stimulation and regulates M-CSF-induced signaling.

Wang Y, Keogh RJ, Hunter MG, Mitchell CA, Frey RS, Javaid K, Malik AB, Schurmans S, Tridandapani S, Marsh CB.

J Immunol. 2004 Dec 1;173(11):6820-30.


Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway.

Bassermann F, Jahn T, Miething C, Seipel P, Bai RY, Coutinho S, Tybulewicz VL, Peschel C, Duyster J.

J Biol Chem. 2002 Apr 5;277(14):12437-45. Epub 2002 Jan 14.


Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav.

Han J, Luby-Phelps K, Das B, Shu X, Xia Y, Mosteller RD, Krishna UM, Falck JR, White MA, Broek D.

Science. 1998 Jan 23;279(5350):558-60.


Activated c-Fms recruits Vav and Rac during CSF-1-induced cytoskeletal remodeling and spreading in osteoclasts.

Sakai H, Chen Y, Itokawa T, Yu KP, Zhu ML, Insogna K.

Bone. 2006 Dec;39(6):1290-301. Epub 2006 Sep 1.


Critical role of the pleckstrin homology and cysteine-rich domains in Vav signaling and transforming activity.

Palmby TR, Abe K, Der CJ.

J Biol Chem. 2002 Oct 18;277(42):39350-9. Epub 2002 Aug 12.


Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages.

Cho YJ, Cunnick JM, Yi SJ, Kaartinen V, Groffen J, Heisterkamp N.

Mol Cell Biol. 2007 Feb;27(3):899-911. Epub 2006 Nov 20.


p85alpha subunit of class IA PI-3 kinase is crucial for macrophage growth and migration.

Munugalavadla V, Borneo J, Ingram DA, Kapur R.

Blood. 2005 Jul 1;106(1):103-9. Epub 2005 Mar 15.


Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages.

Allen WE, Jones GE, Pollard JW, Ridley AJ.

J Cell Sci. 1997 Mar;110 ( Pt 6):707-20.


Activation of Rac by cadherin through the c-Src-Rap1-phosphatidylinositol 3-kinase-Vav2 pathway.

Fukuyama T, Ogita H, Kawakatsu T, Inagaki M, Takai Y.

Oncogene. 2006 Jan 5;25(1):8-19.


Lysophospholipids synergistically promote primitive hematopoietic cell chemotaxis via a mechanism involving Vav 1.

Whetton AD, Lu Y, Pierce A, Carney L, Spooncer E.

Blood. 2003 Oct 15;102(8):2798-802. Epub 2003 Jun 26.

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