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Items: 1 to 20 of 941

1.

GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon.

Guidotti A, Auta J, Davis JM, Dong E, Grayson DR, Veldic M, Zhang X, Costa E.

Psychopharmacology (Berl). 2005 Jul;180(2):191-205. Epub 2005 Apr 28. Review.

PMID:
15864560
2.

A GABAergic cortical deficit dominates schizophrenia pathophysiology.

Costa E, Davis JM, Dong E, Grayson DR, Guidotti A, Tremolizzo L, Veldic M.

Crit Rev Neurobiol. 2004;16(1-2):1-23. Review.

PMID:
15581395
3.

Dendritic spine hypoplasticity and downregulation of reelin and GABAergic tone in schizophrenia vulnerability.

Costa E, Davis J, Grayson DR, Guidotti A, Pappas GD, Pesold C.

Neurobiol Dis. 2001 Oct;8(5):723-42. Review.

PMID:
11592844
4.

Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice.

Tremolizzo L, Doueiri MS, Dong E, Grayson DR, Davis J, Pinna G, Tueting P, Rodriguez-Menendez V, Costa E, Guidotti A.

Biol Psychiatry. 2005 Mar 1;57(5):500-9.

PMID:
15737665
5.

DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains.

Veldic M, Caruncho HJ, Liu WS, Davis J, Satta R, Grayson DR, Guidotti A, Costa E.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):348-53. Epub 2003 Dec 18.

6.

Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study.

Guidotti A, Auta J, Davis JM, Di-Giorgi-Gerevini V, Dwivedi Y, Grayson DR, Impagnatiello F, Pandey G, Pesold C, Sharma R, Uzunov D, Costa E.

Arch Gen Psychiatry. 2000 Nov;57(11):1061-9. Erratum in: Arch Gen Psychiatry 2002 Jan;59(1):12. DiGiorgi Gerevini V [corrected to Di-Giorgi-Gerevini V].

PMID:
11074872
7.

GABAergic dysfunction in mGlu7 receptor-deficient mice as reflected by decreased levels of glutamic acid decarboxylase 65 and 67kDa and increased reelin proteins in the hippocampus.

Wierońska JM, Brański P, Siwek A, Dybala M, Nowak G, Pilc A.

Brain Res. 2010 Jun 2;1334:12-24. doi: 10.1016/j.brainres.2010.03.078. Epub 2010 Mar 29.

PMID:
20353761
8.

In Patas monkey, glutamic acid decarboxylase-67 and reelin mRNA coexpression varies in a manner dependent on layers and cortical areas.

Rodriguez MA, Caruncho HJ, Costa E, Pesold C, Liu WS, Guidotti A.

J Comp Neurol. 2002 Sep 23;451(3):279-88.

PMID:
12210139
9.

The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia.

Grayson DR, Chen Y, Costa E, Dong E, Guidotti A, Kundakovic M, Sharma RP.

Pharmacol Ther. 2006 Jul;111(1):272-86. Epub 2006 Mar 30. Review.

PMID:
16574235
10.

Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia.

Dong E, Agis-Balboa RC, Simonini MV, Grayson DR, Costa E, Guidotti A.

Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12578-83. Epub 2005 Aug 19.

11.

GABAergic cortical neuron chromatin as a putative target to treat schizophrenia vulnerability.

Costa E, Grayson DR, Mitchell CP, Tremolizzo L, Veldic M, Guidotti A.

Crit Rev Neurobiol. 2003;15(2):121-42. Review.

PMID:
14977367
13.

GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and Reelin proteins in cerebellum.

Fatemi SH, Stary JM, Earle JA, Araghi-Niknam M, Eagan E.

Schizophr Res. 2005 Jan 1;72(2-3):109-22. Erratum in: Schizophr Res. 2005 May 1;74(2-3):287. Hossein Fatemi, S [corrected to Fatemi, S Hossein].

PMID:
15560956
14.

Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling.

Guidotti A, Dong E, Kundakovic M, Satta R, Grayson DR, Costa E.

Trends Pharmacol Sci. 2009 Feb;30(2):55-60. doi: 10.1016/j.tips.2008.10.010. Epub 2008 Dec 26.

PMID:
19110320
15.

Reelin depletion in the entorhinal cortex of human amyloid precursor protein transgenic mice and humans with Alzheimer's disease.

Chin J, Massaro CM, Palop JJ, Thwin MT, Yu GQ, Bien-Ly N, Bender A, Mucke L.

J Neurosci. 2007 Mar 14;27(11):2727-33.

16.
17.

Region-specific alteration of GABAergic markers in the brain of heterozygous reeler mice.

Nullmeier S, Panther P, Dobrowolny H, Frotscher M, Zhao S, Schwegler H, Wolf R.

Eur J Neurosci. 2011 Feb;33(4):689-98. doi: 10.1111/j.1460-9568.2010.07563.x. Epub 2011 Jan 13.

PMID:
21226776
18.

A GABA, reelin, and the neurodevelopmental hypothesis of schizophrenia.

Caruncho HJ, Dopeso-Reyes IG, Loza MI, Rodríguez MA.

Crit Rev Neurobiol. 2004;16(1-2):25-32. Review.

PMID:
15581396
19.

[Schizophrenia and cortical GABA neurotransmission].

Hashimoto T, Matsubara T, Lewis DA.

Seishin Shinkeigaku Zasshi. 2010;112(5):439-52. Review. Japanese.

PMID:
20560363
20.

Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation.

Dong E, Nelson M, Grayson DR, Costa E, Guidotti A.

Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13614-9. doi: 10.1073/pnas.0805493105. Epub 2008 Aug 29.

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