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Protection of insulin-producing RINm5F cells against cytokine-mediated toxicity through overexpression of antioxidant enzymes.

Lortz S, Tiedge M, Nachtwey T, Karlsen AE, Nerup J, Lenzen S.

Diabetes. 2000 Jul;49(7):1123-30.

PMID:
10909968
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Suppression of cerulein-induced cytokine expression by antioxidants in pancreatic acinar cells.

Yu JH, Lim JW, Namkung W, Kim H, Kim KH.

Lab Invest. 2002 Oct;82(10):1359-68.

PMID:
12379770
7.

Overexpression of catalase provides partial protection to transgenic mouse beta cells.

Xu B, Moritz JT, Epstein PN.

Free Radic Biol Med. 1999 Oct;27(7-8):830-7.

PMID:
10515587
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9.

Antioxidant enzyme activity and mRNA expression in the islets of Langerhans from the BB/S rat model of type 1 diabetes and an insulin-producing cell line.

Sigfrid LA, Cunningham JM, Beeharry N, Håkan Borg LA, Rosales Hernandez AL, Carlsson C, Bone AJ, Green IC.

J Mol Med (Berl). 2004 May;82(5):325-35. Epub 2004 Mar 9.

PMID:
15007513
11.

Radix clematidis extract protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway.

Kim EK, Song MY, Hwang TO, Kim HJ, Moon WS, Ryu DG, So HS, Park R, Park JW, Kwon KB, Park BH.

Int J Mol Med. 2008 Sep;22(3):349-56.

PMID:
18698494
12.

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis.

Heimberg H, Heremans Y, Jobin C, Leemans R, Cardozo AK, Darville M, Eizirik DL.

Diabetes. 2001 Oct;50(10):2219-24.

13.

Fructus Xanthii extract protects against cytokine-induced damage in pancreatic beta-cells through suppression of NF-kappaB activation.

Song MY, Kim EK, Lee HJ, Park JW, Ryu DG, Kwon KB, Park BH.

Int J Mol Med. 2009 Apr;23(4):547-53.

PMID:
19288032
14.

Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway.

Song MY, Kim EK, Moon WS, Park JW, Kim HJ, So HS, Park R, Kwon KB, Park BH.

Toxicol Appl Pharmacol. 2009 Feb 15;235(1):57-67. doi: 10.1016/j.taap.2008.11.007. Epub 2008 Nov 21.

PMID:
19071154
15.

Radix asari extract protects pancreatic beta cells against cytokine-induced toxicity: implication of the NF-kappaB-iNOS signaling cascade.

Song MY, Kim KA, Lee SY, Kim EK, Lv N, Lee JH, Park JW, Ryu DG, Kwon KB, Park BH.

Int J Mol Med. 2007 Nov;20(5):769-75.

PMID:
17912472
16.

Activation of peroxisome proliferator-activated receptor-gamma protects pancreatic beta-cells from cytokine-induced cytotoxicity via NF kappaB pathway.

Kim EK, Kwon KB, Koo BS, Han MJ, Song MY, Song EK, Han MK, Park JW, Ryu DG, Park BH.

Int J Biochem Cell Biol. 2007;39(6):1260-75. Epub 2007 Apr 19.

PMID:
17521952
17.

Cytokine-mediated induction of anti-apoptotic genes that are linked to nuclear factor kappa-B (NF-kappaB) signalling in human islets and in a mouse beta cell line.

Sarkar SA, Kutlu B, Velmurugan K, Kizaka-Kondoh S, Lee CE, Wong R, Valentine A, Davidson HW, Hutton JC, Pugazhenthi S.

Diabetologia. 2009 Jun;52(6):1092-101. doi: 10.1007/s00125-009-1331-x. Epub 2009 Apr 3.

PMID:
19343319
18.

Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulin-dependent diabetes mellitus.

Welsh N, Margulis B, Borg LA, Wiklund HJ, Saldeen J, Flodström M, Mello MA, Andersson A, Pipeleers DG, Hellerström C, et al.

Mol Med. 1995 Nov;1(7):806-20.

19.

Flavonoids protect against cytokine-induced pancreatic beta-cell damage through suppression of nuclear factor kappaB activation.

Kim EK, Kwon KB, Song MY, Han MJ, Lee JH, Lee YR, Lee JH, Ryu DG, Park BH, Park JW.

Pancreas. 2007 Nov;35(4):e1-9.

PMID:
18090225
20.

A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells.

Cardozo AK, Heimberg H, Heremans Y, Leeman R, Kutlu B, Kruhøffer M, Ørntoft T, Eizirik DL.

J Biol Chem. 2001 Dec 28;276(52):48879-86. Epub 2001 Oct 30.

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