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Results: 1 to 20 of 116

1.

Monoclonal nicotine-specific antibodies reduce nicotine distribution to brain in rats: dose- and affinity-response relationships.

Keyler DE, Roiko SA, Benlhabib E, LeSage MG, St Peter JV, Stewart S, Fuller S, Le CT, Pentel PR.

Drug Metab Dispos. 2005 Jul;33(7):1056-61. Epub 2005 Apr 20.

PMID:
15843487
[PubMed - indexed for MEDLINE]
Free Article
2.

Differential effects of passive immunization with nicotine-specific antibodies on the acute and chronic distribution of nicotine to brain in rats.

Pentel PR, Dufek MB, Roiko SA, Lesage MG, Keyler DE.

J Pharmacol Exp Ther. 2006 May;317(2):660-6. Epub 2006 Jan 11.

PMID:
16407464
[PubMed - indexed for MEDLINE]
Free Article
3.

Maternal vaccination against nicotine reduces nicotine distribution to fetal brain in rats.

Keyler DE, Shoeman D, LeSage MG, Calvin AD, Pentel PR.

J Pharmacol Exp Ther. 2003 May;305(2):587-92. Epub 2003 Feb 11.

PMID:
12606612
[PubMed - indexed for MEDLINE]
Free Article
4.

Combined active and passive immunization enhances the efficacy of immunotherapy against nicotine in rats.

Roiko SA, Harris AC, Keyler DE, Lesage MG, Zhang Y, Pentel PR.

J Pharmacol Exp Ther. 2008 Jun;325(3):985-93. doi: 10.1124/jpet.107.135111. Epub 2008 Feb 27.

PMID:
18305013
[PubMed - indexed for MEDLINE]
Free Article
5.

Reduced nicotine distribution from mother to fetal brain in rats vaccinated against nicotine: time course and influence of nicotine dosing regimen.

Keyler DE, Dufek MB, Calvin AD, Bramwell TJ, LeSage MG, Raphael DE, Ross CA, Le CT, Pentel PR.

Biochem Pharmacol. 2005 May 1;69(9):1385-95.

PMID:
15826609
[PubMed - indexed for MEDLINE]
6.

Immunization of rats reduces nicotine distribution to brain.

Hieda Y, Keyler DE, VanDeVoort JT, Niedbala RS, Raphael DE, Ross CA, Pentel PR.

Psychopharmacology (Berl). 1999 Apr;143(2):150-7.

PMID:
10326777
[PubMed - indexed for MEDLINE]
7.

A nicotine conjugate vaccine reduces nicotine distribution to brain and attenuates its behavioral and cardiovascular effects in rats.

Pentel PR, Malin DH, Ennifar S, Hieda Y, Keyler DE, Lake JR, Milstein JR, Basham LE, Coy RT, Moon JW, Naso R, Fattom A.

Pharmacol Biochem Behav. 2000 Jan 1;65(1):191-8.

PMID:
10638653
[PubMed - indexed for MEDLINE]
8.

Altered disposition of repeated nicotine doses in rats immunized against nicotine.

Keyler DE, Hieda Y, St Peter J, Pentel PR.

Nicotine Tob Res. 1999 Sep;1(3):241-9.

PMID:
11072421
[PubMed - indexed for MEDLINE]
9.

Vaccination against nicotine during continued nicotine administration in rats: immunogenicity of the vaccine and effects on nicotine distribution to brain.

Hieda Y, Keyler DE, Ennifar S, Fattom A, Pentel PR.

Int J Immunopharmacol. 2000 Oct;22(10):809-19.

PMID:
10963853
[PubMed - indexed for MEDLINE]
10.

Tissue-dependent effects of immunization with a nicotine conjugate vaccine on the distribution of nicotine in rats.

Satoskar SD, Keyler DE, LeSage MG, Raphael DE, Ross CA, Pentel PR.

Int Immunopharmacol. 2003 Jul;3(7):957-70.

PMID:
12810353
[PubMed - indexed for MEDLINE]
11.

Combined active and passive immunization against nicotine: minimizing monoclonal antibody requirements using a target antibody concentration strategy.

Cornish KE, Harris AC, LeSage MG, Keyler DE, Burroughs D, Earley C, Pentel PR.

Int Immunopharmacol. 2011 Nov;11(11):1809-15. doi: 10.1016/j.intimp.2011.07.009. Epub 2011 Jul 28.

PMID:
21802529
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Active immunization alters the plasma nicotine concentration in rats.

Hieda Y, Keyler DE, Vandevoort JT, Kane JK, Ross CA, Raphael DE, Niedbalas RS, Pentel PR.

J Pharmacol Exp Ther. 1997 Dec;283(3):1076-81.

PMID:
9399979
[PubMed - indexed for MEDLINE]
Free Article
13.

Effects of nicotine-specific antibodies, Nic311 and Nic-IgG, on the transfer of nicotine across the human placenta.

Nekhayeva IA, Nanovskaya TN, Pentel PR, Keyler DE, Hankins GD, Ahmed MS.

Biochem Pharmacol. 2005 Nov 25;70(11):1664-72. Epub 2005 Oct 11.

PMID:
16223470
[PubMed - indexed for MEDLINE]
14.

Changes in maternal and fetal nicotine distribution after maternal administration of monoclonal nicotine-specific antibody to rats.

Keyler DE, Lesage MG, Dufek MB, Pentel PR.

Int Immunopharmacol. 2006 Nov;6(11):1665-72. Epub 2006 Aug 4.

PMID:
16979120
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Active immunization against nicotine alters the distribution of nicotine but not the metabolism to cotinine in the rat.

de Villiers SH, Lindblom N, Kalayanov G, Gordon S, Johansson AM, Svensson TH.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Oct;370(4):299-304. Epub 2004 Sep 16.

PMID:
15375641
[PubMed - indexed for MEDLINE]
16.

Inhibition of nicotine-induced seizures in rats by combining vaccination against nicotine with chronic nicotine infusion.

Tuncok Y, Hieda Y, Keyler DE, Brown S, Ennifar S, Fattom A, Pentel PR.

Exp Clin Psychopharmacol. 2001 May;9(2):228-34.

PMID:
11518099
[PubMed - indexed for MEDLINE]
17.

Passive immunization against nicotine prevents nicotine alleviation of nicotine abstinence syndrome.

Malin DH, Lake JR, Lin A, SaldaƱa M, Balch L, Irvin ML, Chandrasekara H, Alvarado CL, Hieda Y, Keyler DE, Pentel PR, Ennifar S, Basham LE, Naso R, Fattom A.

Pharmacol Biochem Behav. 2001 Jan;68(1):87-92.

PMID:
11274712
[PubMed - indexed for MEDLINE]
18.

Stereospecific monoclonal antibodies to nicotine and cotinine and their use in enzyme-linked immunosorbent assays.

Bjercke RJ, Cook G, Rychlik N, Gjika HB, Van Vunakis H, Langone JJ.

J Immunol Methods. 1986 Jun 24;90(2):203-13.

PMID:
3722825
[PubMed - indexed for MEDLINE]
19.

Vaccination against nicotine alters the distribution of nicotine delivered via cigarette smoke inhalation to rats.

Pravetoni M, Keyler DE, Raleigh MD, Harris AC, Lesage MG, Mattson CK, Pettersson S, Pentel PR.

Biochem Pharmacol. 2011 May 1;81(9):1164-70. doi: 10.1016/j.bcp.2011.02.004. Epub 2011 Feb 17.

PMID:
21333633
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

[Preparation of polyclonal and monoclonal antibodies against CRF and change of CRF in the sleep-deprived rat brain].

Duan XL, Wang BR, Yang TB, Yu HM, Zhu ZH, Xu Z, Wang X, Wang JT.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2005 Jul;21(4):476-9. Chinese.

PMID:
15989796
[PubMed - indexed for MEDLINE]

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