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Items: 1 to 20 of 150

1.

Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis.

Kaur B, Khwaja FW, Severson EA, Matheny SL, Brat DJ, Van Meir EG.

Neuro Oncol. 2005 Apr;7(2):134-53. Review.

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Silencing hypoxia-inducible factor-1alpha inhibits cell migration and invasion under hypoxic environment in malignant gliomas.

Fujiwara S, Nakagawa K, Harada H, Nagato S, Furukawa K, Teraoka M, Seno T, Oka K, Iwata S, Ohnishi T.

Int J Oncol. 2007 Apr;30(4):793-802.

PMID:
17332917
4.

Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression.

Zagzag D, Zhong H, Scalzitti JM, Laughner E, Simons JW, Semenza GL.

Cancer. 2000 Jun 1;88(11):2606-18.

PMID:
10861440
6.

Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.

Rapisarda A, Uranchimeg B, Scudiero DA, Selby M, Sausville EA, Shoemaker RH, Melillo G.

Cancer Res. 2002 Aug 1;62(15):4316-24.

7.

Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion.

Zagzag D, Lukyanov Y, Lan L, Ali MA, Esencay M, Mendez O, Yee H, Voura EB, Newcomb EW.

Lab Invest. 2006 Dec;86(12):1221-32. Epub 2006 Oct 30.

8.

Mutant IkappaBalpha suppresses hypoxia-induced VEGF expression through downregulation of HIF-1alpha and COX-2 in human glioma cells.

Kimba Y, Abe T, Wu JL, Inoue R, Fukiki M, Kohno K, Kobayashi H.

Oncol Res. 2005;15(3):139-49.

PMID:
16050135
9.

Angiogenesis in gliomas: biology and molecular pathophysiology.

Fischer I, Gagner JP, Law M, Newcomb EW, Zagzag D.

Brain Pathol. 2005 Oct;15(4):297-310. Review.

PMID:
16389942
10.

Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway.

Tan C, de Noronha RG, Roecker AJ, Pyrzynska B, Khwaja F, Zhang Z, Zhang H, Teng Q, Nicholson AC, Giannakakou P, Zhou W, Olson JJ, Pereira MM, Nicolaou KC, Van Meir EG.

Cancer Res. 2005 Jan 15;65(2):605-12.

11.

Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase.

Görlach A, Diebold I, Schini-Kerth VB, Berchner-Pfannschmidt U, Roth U, Brandes RP, Kietzmann T, Busse R.

Circ Res. 2001 Jul 6;89(1):47-54.

12.

Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms.

Damert A, Machein M, Breier G, Fujita MQ, Hanahan D, Risau W, Plate KH.

Cancer Res. 1997 Sep 1;57(17):3860-4.

13.

Inhibition of hypoxia inducible factor 1alpha causes oxygen-independent cytotoxicity and induces p53 independent apoptosis in glioblastoma cells.

Dai S, Huang ML, Hsu CY, Chao KS.

Int J Radiat Oncol Biol Phys. 2003 Mar 15;55(4):1027-36. Erratum in: Int J Radiat Oncol Biol Phys. 2003 Jun 1;56(2):604.

PMID:
12605983
14.

The role of nitric oxide (NO) in stability regulation of hypoxia inducible factor-1alpha (HIF-1alpha).

Brüne B, Zhou J.

Curr Med Chem. 2003 May;10(10):845-55. Review.

PMID:
12678687
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Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors.

Yamakawa M, Liu LX, Date T, Belanger AJ, Vincent KA, Akita GY, Kuriyama T, Cheng SH, Gregory RJ, Jiang C.

Circ Res. 2003 Oct 3;93(7):664-73. Epub 2003 Sep 4.

18.

Hypoxia-inducible factor-1: a molecular hint of physiological changes in the carotid body during long-term hypoxemia?

Fung ML.

Curr Drug Targets Cardiovasc Haematol Disord. 2003 Sep;3(3):254-9. Review.

PMID:
12871043
19.

Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha.

Soeda A, Park M, Lee D, Mintz A, Androutsellis-Theotokis A, McKay RD, Engh J, Iwama T, Kunisada T, Kassam AB, Pollack IF, Park DM.

Oncogene. 2009 Nov 12;28(45):3949-59. doi: 10.1038/onc.2009.252. Epub 2009 Aug 31.

PMID:
19718046
20.

Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1.

Hellwig-Bürgel T, Rutkowski K, Metzen E, Fandrey J, Jelkmann W.

Blood. 1999 Sep 1;94(5):1561-7.

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