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Items: 1 to 20 of 200

1.

The activation of Akt/PKB signaling pathway and cell survival.

Song G, Ouyang G, Bao S.

J Cell Mol Med. 2005 Jan-Mar;9(1):59-71. Review.

2.

The protein kinase B/Akt signalling pathway in human malignancy.

Nicholson KM, Anderson NG.

Cell Signal. 2002 May;14(5):381-95. Review.

PMID:
11882383
3.

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

Kandel ES, Hay N.

Exp Cell Res. 1999 Nov 25;253(1):210-29. Review.

PMID:
10579924
4.

Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members.

DeFeo-Jones D, Barnett SF, Fu S, Hancock PJ, Haskell KM, Leander KR, McAvoy E, Robinson RG, Duggan ME, Lindsley CW, Zhao Z, Huber HE, Jones RE.

Mol Cancer Ther. 2005 Feb;4(2):271-9.

5.

Ultraviolet irradiation activates PI 3-kinase/AKT survival pathway via EGF receptors in human skin in vivo.

Wan YS, Wang ZQ, Shao Y, Voorhees JJ, Fisher GJ.

Int J Oncol. 2001 Mar;18(3):461-6.

PMID:
11179472
6.

Contribution of PKB/AKT signaling to thyroid cancer.

Viglietto G, Amodio N, Malanga D, Scrima M, De Marco C.

Front Biosci (Landmark Ed). 2011 Jan 1;16:1461-87. Review.

PMID:
21196242
7.

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a).

Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME.

Mol Cell Biol. 2001 Feb;21(3):952-65.

8.

p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes.

Genot E, Reif K, Beach S, Kramer I, Cantrell D.

Oncogene. 1998 Oct 1;17(13):1731-8.

9.

Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation.

Okano J, Gaslightwala I, Birnbaum MJ, Rustgi AK, Nakagawa H.

J Biol Chem. 2000 Oct 6;275(40):30934-42.

10.

CH-ILKBP regulates cell survival by facilitating the membrane translocation of protein kinase B/Akt.

Fukuda T, Guo L, Shi X, Wu C.

J Cell Biol. 2003 Mar 31;160(7):1001-8. Epub 2003 Mar 24.

11.

Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane.

Maira SM, Galetic I, Brazil DP, Kaech S, Ingley E, Thelen M, Hemmings BA.

Science. 2001 Oct 12;294(5541):374-80.

12.

Differential activation of the phosphatidylinositol 3'-kinase/Akt survival pathway by ionizing radiation in tumor and primary endothelial cells.

Zingg D, Riesterer O, Fabbro D, Glanzmann C, Bodis S, Pruschy M.

Cancer Res. 2004 Aug 1;64(15):5398-406.

13.

Functional and therapeutic significance of Akt deregulation in malignant melanoma.

Robertson GP.

Cancer Metastasis Rev. 2005 Jun;24(2):273-85. Review.

PMID:
15986137
14.
15.

Structure, regulation and function of PKB/AKT--a major therapeutic target.

Hanada M, Feng J, Hemmings BA.

Biochim Biophys Acta. 2004 Mar 11;1697(1-2):3-16. Review.

PMID:
15023346
16.

Ret oncogene signal transduction via a IRS-2/PI 3-kinase/PKB and a SHC/Grb-2 dependent pathway: possible implication for transforming activity in NIH3T3 cells.

Hennige AM, Lammers R, Arlt D, Höppner W, Strack V, Niederfellner G, Seif FJ, Häring HU, Kellerer M.

Mol Cell Endocrinol. 2000 Sep 25;167(1-2):69-76.

PMID:
11000521
17.

Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors.

Sinha D, Wang Z, Ruchalski KL, Levine JS, Krishnan S, Lieberthal W, Schwartz JH, Borkan SC.

Am J Physiol Renal Physiol. 2005 Apr;288(4):F703-13. Epub 2004 Nov 30.

18.

Mechanical stretch stimulates protein kinase B/Akt phosphorylation in epidermal cells via angiotensin II type 1 receptor and epidermal growth factor receptor.

Kippenberger S, Loitsch S, Guschel M, Müller J, Knies Y, Kaufmann R, Bernd A.

J Biol Chem. 2005 Jan 28;280(4):3060-7. Epub 2004 Nov 15.

19.

Distinct activation mechanisms of protein kinase B by growth-factor stimulation and heat-shock treatment.

Matsuzaki H, Yamamoto T, Kikkawa U.

Biochemistry. 2004 Apr 13;43(14):4284-93.

PMID:
15065872
20.

Unravelling the activation mechanisms of protein kinase B/Akt.

Scheid MP, Woodgett JR.

FEBS Lett. 2003 Jul 3;546(1):108-12. Review.

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