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Results: 1 to 20 of 291

1.

The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression.

Xiao GH, Gallagher R, Shetler J, Skele K, Altomare DA, Pestell RG, Jhanwar S, Testa JR.

Mol Cell Biol. 2005 Mar;25(6):2384-94.

PMID:
15743831
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Re-expression of the tumor suppressor NF2/merlin inhibits invasiveness in mesothelioma cells and negatively regulates FAK.

Poulikakos PI, Xiao GH, Gallagher R, Jablonski S, Jhanwar SC, Testa JR.

Oncogene. 2006 Sep 28;25(44):5960-8. Epub 2006 May 1.

PMID:
16652148
[PubMed - indexed for MEDLINE]
3.

Inactivation of the NF2 tumor suppressor protein merlin in DU145 prostate cancer cells.

Horiguchi A, Zheng R, Shen R, Nanus DM.

Prostate. 2008 Jun 15;68(9):975-84. doi: 10.1002/pros.20760.

PMID:
18361411
[PubMed - indexed for MEDLINE]
4.

Compensative shuttling of merlin to phosphorylation on serine 518 in vestibular schwannoma.

Lü J, Zou J, Wu H, Cai L.

Laryngoscope. 2008 Jan;118(1):169-74.

PMID:
17989580
[PubMed - indexed for MEDLINE]
5.

p21-activated kinase links Rac/Cdc42 signaling to merlin.

Xiao GH, Beeser A, Chernoff J, Testa JR.

J Biol Chem. 2002 Jan 11;277(2):883-6. Epub 2001 Nov 21.

PMID:
11719502
[PubMed - indexed for MEDLINE]
Free Article
6.

Inhibition of ras-mediated activator protein 1 activity and cell growth by merlin.

Kim H, Lim JY, Kim YH, Kim H, Park SH, Lee KH, Han H, Jeun SS, Lee JH, Rha HK.

Mol Cells. 2002 Aug 31;14(1):108-14.

PMID:
12243339
[PubMed - indexed for MEDLINE]
Free Article
7.

Involvement of p21 (waf1) in merlin deficient sporadic vestibular schwannomas.

Wu H, Chen Y, Wang ZY, Li W, Li JQ, Zhang L, Lu YJ.

Neuroscience. 2010 Sep 29;170(1):149-55. doi: 10.1016/j.neuroscience.2010.06.051. Epub 2010 Jul 1.

PMID:
20600642
[PubMed - indexed for MEDLINE]
8.

Loss of the tumor suppressor gene NF2, encoding merlin, constitutively activates integrin-dependent mTORC1 signaling.

López-Lago MA, Okada T, Murillo MM, Socci N, Giancotti FG.

Mol Cell Biol. 2009 Aug;29(15):4235-49. doi: 10.1128/MCB.01578-08. Epub 2009 May 18.

PMID:
19451229
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1.

Kissil JL, Wilker EW, Johnson KC, Eckman MS, Yaffe MB, Jacks T.

Mol Cell. 2003 Oct;12(4):841-9.

PMID:
14580336
[PubMed - indexed for MEDLINE]
10.

The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP.

Striedinger K, VandenBerg SR, Baia GS, McDermott MW, Gutmann DH, Lal A.

Neoplasia. 2008 Nov;10(11):1204-12.

PMID:
18953429
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Inhibition of the hyaluronan-CD44 interaction by merlin contributes to the tumor-suppressor activity of merlin.

Bai Y, Liu YJ, Wang H, Xu Y, Stamenkovic I, Yu Q.

Oncogene. 2007 Feb 8;26(6):836-50. Epub 2006 Sep 4.

PMID:
16953231
[PubMed - indexed for MEDLINE]
12.

Differential role of diphenyleneiodonium, a flavoenzyme inhibitor, on p53-dependent and -independent cell cycle progression.

Song JD, Kim KM, Kim KH, Kim CD, Kim JM, Yoo YH, Park YC.

Int J Oncol. 2008 Dec;33(6):1299-306.

PMID:
19020764
[PubMed - indexed for MEDLINE]
13.

p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells.

Balasenthil S, Sahin AA, Barnes CJ, Wang RA, Pestell RG, Vadlamudi RK, Kumar R.

J Biol Chem. 2004 Jan 9;279(2):1422-8. Epub 2003 Oct 6.

PMID:
14530270
[PubMed - indexed for MEDLINE]
Free Article
14.

Tumor suppression by IFN regulatory factor-1 is mediated by transcriptional down-regulation of cyclin D1.

Kröger A, Stirnweiss A, Pulverer JE, Klages K, Grashoff M, Reimann J, Hauser H.

Cancer Res. 2007 Apr 1;67(7):2972-81.

PMID:
17409403
[PubMed - indexed for MEDLINE]
Free Article
15.

Evidence that leptin through STAT and CREB signaling enhances cyclin D1 expression and promotes human endometrial cancer proliferation.

Catalano S, Giordano C, Rizza P, Gu G, Barone I, Bonofiglio D, Giordano F, Malivindi R, Gaccione D, Lanzino M, De Amicis F, Andò S.

J Cell Physiol. 2009 Mar;218(3):490-500. doi: 10.1002/jcp.21622.

PMID:
18988190
[PubMed - indexed for MEDLINE]
16.

Arginine vasopressin inhibition of cyclin D1 gene expression blocks the cell cycle and cell proliferation in the mouse Y1 adrenocortical tumor cell line.

Schwindt TT, Forti FL, Juliano MA, Juliano L, Armelin HA.

Biochemistry. 2003 Feb 25;42(7):2116-21.

PMID:
12590600
[PubMed - indexed for MEDLINE]
17.

A clue to the therapy of neurofibromatosis type 2: NF2/merlin is a PAK1 inhibitor.

Hirokawa Y, Tikoo A, Huynh J, Utermark T, Hanemann CO, Giovannini M, Xiao GH, Testa JR, Wood J, Maruta H.

Cancer J. 2004 Jan-Feb;10(1):20-6.

PMID:
15000491
[PubMed - indexed for MEDLINE]
18.

The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.

Shaw RJ, Paez JG, Curto M, Yaktine A, Pruitt WM, Saotome I, O'Bryan JP, Gupta V, Ratner N, Der CJ, Jacks T, McClatchey AI.

Dev Cell. 2001 Jul;1(1):63-72.

PMID:
11703924
[PubMed - indexed for MEDLINE]
Free Article
19.

[Inhibitory effect of wild-type RASSF1A gene expression on proliferation of hepatocellular carcinoma QGY-7703 cells].

Rui L, Xue WJ, Li P, Wang ZW, Wang P, Li HX.

Ai Zheng. 2008 Sep;27(9):924-8. Chinese.

PMID:
18799029
[PubMed - indexed for MEDLINE]
20.

p53 inhibits adriamycin-induced down-regulation of cyclin D1 expression in human cancer cells.

Shao J, Teraishi F, Katsuda K, Tanaka N, Fujiwara T.

Biochem Biophys Res Commun. 2002 Jan 25;290(3):1101-7.

PMID:
11798189
[PubMed - indexed for MEDLINE]

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